Research Projects

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Overview

There are over 20 projects that are currently being done by the faculty and staff of the department. Some of there are in collaboration with international as well as with other Indian institutes and companies.

  • Nano technology for enhanced utilization of native-phosphorous by plants and higher moisture retention in arid soils

    (PI: Dr. Jitendra Panwar) “Nano technology for enhanced utilization of native-phosphorous by plants and higher moisture retention in arid soils” Funding Agency: Indian Council of Agricultural Research (ICAR), Govt. of India, New Delhi; Sanctioned Amount: 6.147119 Crore (41.539 Lakh); Duration: 6 Years (2008-2014).

  • Mechanistic studies on extracellular biosynthesis of metal nanoparticles

    (PI: Dr. Jitendra Panwar) “Mechanistic studies on extracellular biosynthesis of metal  nanoparticles” Funding Agency: Department of Science & Technology (DST), Govt. of India, New Delhi; Sanctioned Amount: 45.5 Lakh; Duration: 3 Years (2013-2016).

  • Characterization of immune signaling pathway in Anopheles mosquitoes

    (PI: Dr. Lalita Gupta) “Characterization of immune signaling pathway in Anopheles mosquitoes” Funding Agency: Department of Science & Technology (DST), Govt. of India, New Delhi; 21.2 Lakhs, Duration: 3 years (2012-2015).

  • Phytochemical and Metabolic Characterization of Prosopis cineraria pods (sangri) as potential nutraceuticals

    (PI: Dr. Pankaj Kumar Sharma) “Phytochemical and Metabolic Characterization of Prosopis cineraria pods (sangri) as potential nutraceuticals” Funding Agency: SERB- Department of Science & Technology (DST), Govt. of India, New Delhi; Sanctioned amount Rs. 21.3 Lakhs. Duration: 3 years (2012-2015)

  • Molecular Characterization of ACC (1-aminocyclopropane-1-carboxylate) Deaminase Activity of Associative Bacteria Isolated from Plants of Desert of Rajasthan

    (PI: Dr. Prabhat Nath Jha, Co PI: Dr. S.K. Verma, Dr. Rajesh Mehrotra,) “Molecular Characterization of ACC (1-aminocyclopropane-1-carboxylate) Deaminase Activity of Associative Bacteria Isolated from Plants of Desert of Rajasthan”. Funding Agency: Department of Biotechnology, Govt of India, New Delhi; Sanctioned amount: 41.35 Lakh. Duration: 3 years (2012-2015).

  • Role of Pro-inflammatory Cytokines in Epithelial to Mesenchymal Transition in Hepatocellular Carcinoma

    (PI: Dr. Rajdeep Chowdhury) “Role of Pro-inflammatory Cytokines in Epithelial to Mesenchymal Transition in Hepatocellular Carcinoma”. Funding Agency: Research Initiation Grant, BITS Pilani; Sanctioned amount: 2 Lakhs; Duration: 2 years (2013-2015).

  • Role of Hippo Signaling Pathway Components in Autophagy Regulation in Hepatocellular Carcinoma

    (PI: Dr. Rajdeep Chowdhury) “Role of Hippo Signaling Pathway Components in Autophagy Regulation in Hepatocellular Carcinoma". Funding Agency: SERB- Department of Science & Technology (DST), Govt. of India, New Delhi; Sanctioned amount: 24 Lakhs; Duration: 3 years (2013-16).

  • Identifying microRNA Signatures Associated with Autophagy Induced Chemoresistance in Hepatocellular Carcinoma

    (PI: Dr. Rajdeep Chowdhury) “"Identifying microRNA Signatures Associated with Autophagy Induced Chemoresistance in Hepatocellular Carcinoma". Funding Agency:  UGC, New Delhi, India, Sanctioned amount: 6 lakhs Duration: 2013-15.

  • Analyzing structural and functional evolutionary relationship between RubisCO and carbon concentrating mechanism proteins

    (PI: Dr. Sandhya Mehrotra):  SERB fast track project entitled, "Analyzing structural and functional evolutionary relationship between RubisCO and carbon concentrating mechanism proteins”. Funding agency: SERB- Department of Science and Technology, Govt of India. Sanctioned amount: 23.96 Lakhs. Duration; 3 years (2013-16). 

  • Molecular characterization of Anopheles stephensi guts epithelial peroxidases and their role in modulating immunity against bacterial and fungal antigens

    (PI: Dr. Sanjeev Kumar, Co-PI: Lalita Gupta) “Molecular characterization of Anopheles stephensi guts epithelial peroxidases and their role in modulating immunity against bacterial and fungal antigens” Funding Agency: Department of Science and Technology, New Delhi, Sanctiioned amount: 47.18 Lakhs, Duration: 3 years (2012-15).

  • Enzymatic kinetic resolution of racemic amidoalkyl naphthols and their derivatives

    (PI: Dr. Santosh Kumar Padhi): “Enzymatic kinetic resolution of racemic amidoalkyl naphthols and their derivatives”. Funding Agency: Research Initiation Grant, BITS Pilani, Sanctioned amount 2.00 lacs; Duration: 2 years (2012-2014).

  • Enzyme Catalyzed Kinetic Resolution of (a) Racemic Amidoalkylnaphthols and (b) Racemic 1-Amidomethyl-Imidazo[1,2-a]Pyridines

    (PI: Dr. Santosh Kumar Padhi): "Enzyme Catalyzed Kinetic Resolution of (a) Racemic Amidoalkylnaphthols and (b) Racemic 1-Amidomethyl-Imidazo[1,2-a]Pyridines". Funding Agency:  UGC, New Delhi, India, Sanctioned Amount : 6 Lakhs; Duration: 2 years (2013 -  2015).

  • Engineering Baliospermum montanum Hydroxynitrile lyase for Potential Synthetic and Industrial Applications

    (PI: Dr. Santosh Kumar Padhi) : "Engineering Baliospermum montanum Hydroxynitrile lyase for Potential Synthetic and Industrial Applications" Funding Agency : Science & Engineering Research Board (SERB) -New Delhi, India, Sanctioned amount : 25 Lakhs ; Duration:3 years (2013 -  2016).

  • A mechanistic analysis of the role of pro-inflammatory cytokines in induction of epithelial to mesenchymal transition in hepatocellular carcinoma

    (PI: Dr. Sudeshna Mukherjee Chowdhury) “A mechanistic analysis of the role of pro-inflammatory cytokines in induction of epithelial to mesenchymal transition in hepatocellular carcinoma”, Funding agency: DST FAST Track (Young Scientist), Sanctioned amount: 17 Lakhs; Duration: 3 years (2013-16).

  • Role of conserved oligomeric golgi complex (COG7) gene in the morophogenesis of hearing organ of Drosophila

    (PI: Dr. Monalisa Mishra) “Role of conserved oligomeric golgi complex (COG7) gene in the morophogenesis of hearing organ of Drosophila”, Funding Agency: Department of Science and Technology, India. Sanctioned amount: 23.75 lakhs, Duration: 3 years.

  • Role of PKD in the eye development of Drosophila

    (PI: Dr. Monalisa Mishra) “Role of PKD in the eye development of Drosophila”, Funding Agency: UGC, New Delhi; Sanctioned amount: 6 lakhs; Duration: 2 years.

  • Identification of microRNAs Affecting LCAT and apoB-100 during Inflammatory Stress

    (PI: Dr. Praphulla C Shukla): "Identification of microRNAs Affecting LCAT and apoB-100 during Inflammatory Stress", Funding Agency: UGC, New Delhi; Sanctioned amount: 6 Lakhs; Duration: 2 years.

  • Analysis of Genetic diversity of malaria parasite using genetic and microsatellite markers from Bikaner, India

    (PI: Dr. Shilpi Garg): "Analysis of Genetic diversity of malaria parasite using genetic and microsatellite markers from Bikaner, India". Funding agency:  Research Initiation Grant, BITS Pilani, Sanctioned amount: 2 lakhs; Duration: 2 years (2012-2014).

  • Endophytic bacteria mediated phytoremediation of organic pollutants

    (PI: Dr. Prameela Jha): “Endophytic bacteria mediated phytoremediation of organic pollutants”. Funding Agency: Department of Science and technology, India. Sanctioned amount: 25.10 lakhs; Duration: 3 years (2012-2015).

  • To Investigate the Effect of Fatty Acid Synthase (FASN) siRNA in a FASN expressing cancer cell line

    (PI: Dr. P.R. Deepa) “To Investigate the Effect of Fatty Acid Synthase (FASN) siRNA in a FASN expressing cancer cell line”. Funded by: ICMR, New Delhi; Sanctioned Amount: ~24 Lakhs; Duration: 3 years (2011-2014).

  • Identification of potential molecular inhibitors of all catalytic domains of Fattyacid synthase (FASN) at the enzyme activity and gene expression level

    (PI: Dr. P.R. Deepa) “Identification of potential molecular inhibitors of all catalytic domains of Fattyacid synthase (FASN) at the enzyme activity and gene expression level”; Funded By: Department of Biotechnology (DBT), Govt. of India; Sanctioned Amount: Rs. 33.67 lakhs; Duration: 3 years (2012 –2015).

  • Cardiovascular Disease in human population: Mathematical modeling and analysis of its incidence, risk factors, and preventive strategies

    (Co-PI: Dr. P.R. Deepa) “Cardiovascular Disease in human population: Mathematical modeling and analysis of its incidence, risk factors, and preventive strategies”; Funded by: UGC, New Delhi; Sanctioned Amount: 8.44 Lakhs; Duration: 3 Years (2011- 2014).

  • Designing, synthesis and validation of a dehydration stress responsive promoter in plants

    (PI: Dr. Sandhya Mehrotra; Co-PI: Dr. Rajesh Mehrotra) " Designing, synthesis and validation of a dehydration stress responsive promoter in plants". Funded by: UGC, New Delhi; Sanctioned Amount: 12.88 Lakhs; Duration: 3 years (2014-17).

  • Bioleaching of copper from low grade ore at Hindustan Copper Limited, HCL Khetri

    (Co-PI: Dr. S K Verma) "Bioleaching of copper from low grade ore at Hindustan Copper Limited, HCL Khetri". Funded by: Ministry of Mines; Sanctioned Amount: 30.38 Lakhs; Duration: 3 years (2014-17).

  • Characterization of Isoprenoid biosynthetic pathway enzymes from Plasmodium vivax

    (PI: Dr. Vishal Saxena): "Characterization of Isoprenoid biosynthetic pathway enzymes from Plasmodium vivax". Funding Agency: UGC Major Research Project, UGC New Delhi; Sanctioned Amount: 8 Lakhs; Duration: 3 years (2013-2016).

  • Enhancing phytochemical production by the use of elicitors

    (PI: Dr. Shachi Singh) "Enhancing phytochemical production by the use of elicitors". Funding Agency: Department of Science and Technology (DST)-Science and Engineering Research Board (SERB), Govt. of India, New Delhi; Sanctioned Amount (21.8 Lakh); Duration: 3 years (2013-2016)
     
     
     

  • Projects Completed

    • (PI: Dr. S K Verma) " Bio-Diesel production from microalgae” Duration: 3 years; Sanctioned Amount: 19.57 Lakhs, Funding Agency: CSIR, New Delhi.
    • (PI: Dr. S K Verma) "Characterization and Pharmacological evaluation of bioactive compounds from cyanobacterial isolates from Shekhawati region of Rajasthan" Duration: 3 years; Sanctioned Amount: 6.26 Lakhs, Funding Agency: UGC, New Delhi.
    • (PI: Dr. S K Verma) "Development of Bacterial Biosensor for antibiotic detection" Duration: 3 years; Sanctioned Amount: 4.35 Lakhs, Funding Agency: UGC, New Delhi.
    • (PI: Dr. S K Verma) "Development of recombinant DNA based Biosensor device for detection of arsenic in water samples” Duration: 2 years; Sanctioned Amount: 33.8 Lakhs Funding Agency: DST, New Delhi.
    • (PI: Dr. AK Das) "Cloning and characterization of the regions of the apicoplast genome from P.vivax". Duration: 3 years; Sanctioned Amount: 9.95 Lakhs, Funding Agency: UGC, New Delhi.
    • (PI: Dr. AK Das) "Development of comprehensive diagnostic system for P.falciparum, P.vivax and P.malariae" Duration: 3 years; Sanctioned Amount: 8 Lakhs, Funding Agency: CSIR, New Delhi.
    • (PI: Dr. AK Das) "Prokaryotic vector design using cryptic plasmid from Leuconostoc, Lactobacillus and Cyanobacterial sp."; Sanctioned Amount: 12 Lakhs, Funding Agency: Dabur Research Foundation; (funding ceased after re-organization of DRF into a CRO).
    • (PI: Dr. AK Das) "A Systems Biology Approach Towards Understanding Severe Malaria with Special Reference to the Transcriptome and Proteome of the Parasite and the Host" Duration: 3 years; Sanctioned amount: 18.8 Lakhs; Funding Agency: DBT, New Delhi.
    • (Dr. Uma S. Dubey, Co-PI; PI: S. Kapur) “Functional Mutations in the Opiod Receptors and their impact on immune cell function” Duration: 4 years; Sanctioned amount: 55.76 Lakhs; Funding Agency: Indian Council for Medical Research, New Delhi.
    • (PI: Dr. S Chowdhury) "In-silico Characterization of Non-native Structural ensembles of Small Proteins and peptides and its implications on Protein folding and Misfolding process. Duration: 3 years; Sanctioned amount: 7.68 Lakhs; Funding Agency: DST, New Delhi.
    • (PI: Dr. B Vani) "Signaling Mechanism and nitrate assimilation in the Cyanobacterium Spirulina platensis" Duration: 3 years; Sanctioned amount: 7.62 Lakhs; Funding Agency: DST, New Delhi.
    • (PI: Dr. Lalita Gupta)  “Characterization of immune signaling pathway in Anopheles mosquitoes for arresting Plasmodium development” Duration: 2 Years, Sanctioned Amount: 10 Lakhs; Funding Agency: Aditya Birla Groups.
    • (PI: Dr. Rajesh Mehrotra, Co-PIs: Jitendra Panwar, Sandhya Mehrotra) “Natural and Engineered Lipases for Biodiesel Production” Duration: 2 Years; Sanctioned Amount: 10 Lakhs; Funding Agency: Aditya Birla Group (ABG), Mumbai.
    • (PI: Dr. Rajesh Mehrotra) “Cloning and characterization of protein phosphatase2C (PP2C) like promoter from Arabidopsis thaliana”; Duration: 3 Years; Sanctioned Amount: 12.57 Lakhs; Funding Agency: DST, New Delhi.
    • (PI: Dr. Prabhat Nath Jha): Molecular Characterization of diazotrophic plant growth-promoting endophytic bacteria isolated from arid desert of Rajasthan. Sanctioned Amount: 14.51 Lakhs, Funding Agency: DST, New Delhi.
    • (PI: Dr. Vishal Saxena): "Cloning and Characterization of the major regions of the plastid DNA from Plasmodium vivax". Duration: 3 years; Funding Agency: DST- Young Scientist, New Delhi.

MOU Signed with National Institute of Health, USA

BITS, Pilani has signed a MOU with National Institute of Health, USA for research collaboration in the area of epigenetics and human health. The collaboration is aimed at students and faculty exchange programme for completing doctoral thesis work.

 

An institution deemed to be a University estd. vide Sec.3 of the UGC Act,1956 under notification # F.12-23/63.U-2 of Jun 18,1964

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