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Prof. Trinath Jamma

Associate Professor
Department of Biological Sciences

Inflammatory Cell Signaling and Immune Cell Metabolism
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Research Publications

After Joining BITS: 

  1. Purbali A, Trinath J, Sajeli A, Yogeeswari P. Combining Structure-based and 3D QSAR Pharmacophore Models to Discover Diverse Ligands against EGFR in Oral Cancer. Future Medicinal Chemistry(Accepted, January 2022).
  2. Eugene SP, Trinath J*. Endoplasmic Reticulum Stress in Intestinal Inflammation: Implications of Bile Acids. Accepted, PINSA, India. 2021 *Corresponding author.
  3. V. Sudhakar Reddy, Trinath Jamma, and G. Bhanuprakash Reddy. Small Heat Shock Proteins in Inflammatory Diseases. Book Chapter Accepted. Heat Shock Protein Journal.
  4. Saxena S, Maroju PA, Choudhury S, Voina VC, Naik P, Gowdhaman K, Kkani P, Chennoju K, Ganesh Kumar S, Ramasubramanian C, Prasad Rao G,  Functional Analysis of DNMT1 SNPs (rs2228611 and rs2114724) Associated with Schizophrenia.  Jamma T, Narayan KP, Mohan KN.Genet Res (Camb).2021:6698979. doi: 10.1155/2021/6698979.
  5. Eugene SP, Reddy VS, Trinath J*. Endoplasmic Reticulum Stress and Intestinal Inflammation: A Perilous Union. Front Immunol. 2020; 11:543022. * Corresponding author.
  6. Hang S, Paik D, Yao L, Kim E, Jamma T, Lu J, Ha S, Nelson BN, Kelly SP, Wu L, Zheng Y, Longman RS, Rastinejad F, Devlin AS, Krout MR, Fischbach MA, Littman DR, Huh JR. Bile acid metabolites control Th17 and Treg cell differentiation. Nature. 2019;576(7785):143-148.1. 
  7. Reddy VS, Trinath J, Reddy GB. Implications of homocysteine in protein quality and control processes. Biochimie. 2019;165:19-31.  
  8. Trinath J, Bayry J. Current trends with FOXP3+ regulatory T cell immunotherapy to contest autoimmunity and inflammation. Immunotherapy. 2019;11(9):755-758.
  9. Reddy VS,  Madala SK, Trinath J, Reddy GB. Extracellular small heat shock proteins: exosomal biogenesis  and  function. Cell Stress Chaperones. 2018;23(3):441-454.

 

Before Joining BITS: 

  1. Mohan S Maddur, Emmanuel Stephen-Victor, Mrinmoy Das, Praveen Prakhar, Varun K Sharma, Vikas Singh, Magalie Rabin, Trinath J, Kithiganahalli N Balaji, Francis Bolgert, Jean-Michel Vallat, Laurent Magy, Srini V Kaveri, Jagadeesh Bayry. (2017). Regulatory T cell frequency, but not plasma IL-33 levels represents potential immunological biomarker to predict clinical response to intravenous immunoglobulin therapy. J Neroinflammation. 14(1):58.
  2. Maddur MS, Trinath J, Rabin M, Bolgert F, Guy M, Vallat JM, Magy L, Balaji KN, Kaveri SV, Bayry J. (2015). Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation. Cell Mol Immunol. 12(5):650-2.
  3. Prasad KD*, Trinath J*, Biswas A, Sekar K, Balaji KN, Guru Row TN. (2014). Anthrapyrazolone analogues intercept inflammatory JNK signals to moderate endotoxin induced septic shock. Sci Rep.4: 7214. *Equally contributed.
  4. Trinath J*, Holla S*, Mahadik K, Prakhar P, Singh V, Balaji KN. (2014). The WNT signaling pathway contributes to dectin-1-dependent inhibition of Toll-like receptor-induced inflammatory signature. Mol Cell Biol. 34(23): 4301-14. *Equally contributed.
  5. Prasad KD, Trinath J, Biswas A, Sekar K, Balaji KN, Guru Row TN. (2014). Alkyl chain substituted 1,9-pyrazoloanthrones exhibit prominent inhibitory effect on c-Jun N-terminal kinase (JNK). Org Biomol Chem. 12(26): 4656-62.
  6. Trinath J*, Hegde P*, Sharma M*, Maddur MS, Rabin M, Vallat JM, Magy L, Balaji KN, Kaveri SV, Bayry J.(2013) Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells. Blood. 22(8): 1419-27. *Equally contributed.
  7. Vani J, Shaila MS, Trinath J, Balaji KN, Kaveri SV, Bayry J. (2013). Mycobacterium tuberculosis cell wall-associated Rv3812 protein induces strong dendritic cell-mediated interferon γ responses and exhibits vaccine potential. J Infect Dis. 208(6): 1034-6.
  8. Trinath J, Hegde P, Balaji KN, Kaveri SV, Bayry J. (2013). Intravenous immunoglobulin-mediated regulation of Notch ligands on human dendritic cells. J Allergy Clin Immunol. 131(4): 1255-7.
  9. Trinath J, Maddur MS, Kaveri SV, Balaji KN, Bayry J. (2012). Mycobacterium tuberculosis promotes regulatory T-cell expansion via induction of programmed death-1 ligand 1 (PD-L1, CD274) on dendritic cells. J Infect Dis. 205(4): 694-6.

 

Book Chapter:

  1. Holla S,  Trinath J, Balaji KN. (2014). TNF-α modulates TLR2-dependent responses during  mycobacterial infection. Methods Mol Biol. 1155:133-50.