Surfactant-Free, Self-Assembling Micelles of Fatty Acid Conjugated to Hydrophilic Drug and Method for Preparing the Same
Inventors:
Dr. Anupama Mittal , Kishan Italiya Samjibhai, Samrat Mazumdar, Prof. Deepak Chitkara
Existing diabetes therapies have significant limitations like short action duration, risk of hypoglycemia, and need for parenteral administration; lysofylline's high solubility hinders encapsulation.
The invention provides surfactant-free, self-assembling micelles of fatty acid conjugated to lysofylline, offering a novel delivery system enhancing drug encapsulation and stability.
Innovatively conjugating linoleic acid with the hydrophilic drug lysofylline to form surfactant-free, self-assembling micelles, this method improves drug hydrophobicity and encapsulation efficiency, marking a significant advancement in diabetes treatment delivery systems
Potential Indian Clients: Pharmaceutical companies focusing on diabetes treatment, research institutions, hospitals, and diabetic care centers.
Current TRL: NA
Funded by: NA
IPC: C08L
Domain: Pharmaceutical Technology
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