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Patent Number:- IN456869

Synthesis of New Triazolyl Linked Bile Acid Aryl Ketones

  • Sector: Organic Chemistry,
  • IPC: C07D, C07J,
 

Need

There is a need for an efficient methodology for synthesizing C-24 functionalized triazolyl linked bile acid-derived aryl ketones in a one-pot multicomponent manner.

Solution

The present disclosure offers a process for synthesizing compounds of formula (I) containing C-24 functionalized bile acid derivatives.

Innovation

The novel synthesis method of compounds represented by formula (I), combining C-24 functionalized bile acid, triazolyl moiety, and keto-aryl moiety efficiently, enabling potential pharmaceutical applications with broad economic significance in drug development and healthcare.

Market Analysis

Market:Global oncology/cancer treatment market.

CAGR: The global cancer therapeutics market is expected to grow at a CAGR of around 7.2% from 2020 to 2027.

Potential Indian Clients: Sun Pharmaceutical Industries Ltd., Biocon Ltd., Dr. Reddy’s Laboratories Ltd..

Why Invest?


Synthesis

Endogenous steroids

Bile acid derivatives

Anticancer agents

At a Glance


Current TRL: NA

Funded by: NA

IPC: C07D, C07J

Domain: Pharmaceutical development, specifically steroid-based anticancer agents.

For more information, reach out to Mr. Rajneesh Kumar, Head of the Technology Transfer Office, at tto@bits-pilani.ac.in and 01596-255515.