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Indrani Talukdar

Associate Professor

Alternative splicing, metabolic syndromes, stem cell biology
Indrani Talukdar

List of Publications

1) Arachidonic Acid Inhibits the Insulin Induction of Glucose-6-phosphate Dehydrogenase via p38 MAP Kinase. Indrani Talukdar, Wioletta Szeszel-Fedorowicz, and Lisa M. Salati., J Biol Chem. 2005 Dec 9;280(49):40660-7. Epub 2005 Oct 6., PMID: 16210322 

2) An Exonic Splicing Silencer is Involved in the Regulated Splicing of Glucose 6- phosphate
Dehydrogenase mRNA. Wioletta Szeszel-Fedorowicz, Indrani Talukdar, Brain N. Griffith, Callee M. Walsh, and Lisa M. Salati., J Biol Chem. 2006 Nov 10;281(45):34146-58. Epub 2006 Sep 15., PMID: 16980303
 

3) Pulse Sensitivity of the LH{beta} Promoter is Determined by a Negative Feedback Loop Involving Egr1 and Nab1/2. Mark A. Lawson, Rie Tsutsumi, Hao Zhang, Indrani Talukdar, Brian K. Butler, Sharon J. Santos, Pamela L. Mellon, and Nicholas J.G. Webster., Mol Endocrinol. 2007 Feb 13; PMID: 17299135

4) SRp20, CUG-BP1 and hnRNP A1 binding to IR exon 11 modulate its alternative splicing, Supriya Sen*, Indrani Talukdar* and Nicholas JG Webster, Mol Cell Biol. 2009 Feb;29(3):871-80. Epub 2008 Dec 1. * Both authors contributed equally to the work.

5) A role for AMPK in the inhibition of glucose-6-phosphate dehydrogenase by polyunsaturated fatty acids, Kohan AB*, Talukdar I* , Walsh CM and Salati LM. Biochem Biophys Res Commun. 2009 Oct 9;388(1):117-21. Epub 2009 Jul 30 * Both authors contributed equally to the work.

6) Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer. Sen S, Talukdar I, Liu Y, Tam J, Reddy S, Webster NJ. J Biol Chem. 2010 Aug 13;285(33):25426-37. Epub 2010 Jun 2.

7) hnRNP A1 and hnRNP F modulate the alternative splicing of exon 11 of the insulin receptor gene. Talukdar I*, Sen S*, Urbano R, Thompson J, Yates JR 3rd, Webster NJ, PLoS One. 2011;6(11):e27869. Epub 2011 Nov 23 * Both authors contributed equally to the work.

8) Kinome-wide Functional Analysis Highlights the Role of Cytoskeletal Remodeling in Somatic Cell Reprogramming. Sakurai K*, Talukdar I*, Patil VS*, Dang J, Li Z, Chang KY, Lu CC, Delorme-Walker V, Dermardirossian C, Anderson K, Hanein D, Yang CS, Wu D, Liu Y, Rana TM.
Cell Stem Cell. 2014 Apr 3;14(4):523-34. doi: 10.1016/j.stem.2014.03.001.
* All these authors contributed equally to the work.

9) Louis JM, Vaz C, Balaji A, Tanavde V, Talukdar I. TNF-alpha regulates alternative splicing of genes participating in pathways of crucial metabolic syndromes; a transcriptome wide study. Cytokine. 2020 Jan;125:154815. doi: 10.1016/j.cyto.2019.154815. Epub 2019 Aug 30. PMID: 31476685.

10) Banerjee, S., Talukdar, I., Banerjee, A., Gupta, A., Balaji, A., & Aduri, R. (2019). Type II diabetes mellitus and obesity: Common links, existing therapeutics and future developments. Journal of Biosciences, 44(6), 150.

11) Fernandes F, Kotharkar P, Chakravorty A, Kowshik M, Talukdar I. Nanocarrier Mediated siRNA Delivery Targeting Stem Cell Differentiation. Curr Stem Cell Res Ther. 2020;15(2):155-172. doi: 10.2174/1574888X14666191202095041. PMID: 31789134.

12) Louis, J. M., Agarwal, A., Aduri, R., & Talukdar, I. (2021). Global analysis of RNA–protein interactions in TNF‐α induced alternative splicing in metabolic disorders. FEBS letters595(4), 476-490.

13) Zantye, P., Shende, S., Ramanan, S. R., Talukdar, I., & Kowshik, M. (2021). Design of a Biocompatible Hydroxyapatite-Based Nanovehicle for Efficient Delivery of Small Interference Ribonucleic Acid into Mouse Embryonic Stem Cells. Molecular Pharmaceutics, 18(3), 796-806.

14) Louis, J. M., Agarwal, A., Mondal, S., & Talukdar, I. (2022). A global analysis on the differential regulation of RNA binding proteins (RBPs) by TNF–α as potential modulators of metabolic syndromes. BBA Advances2, 100037.

15) Pranjita Zantye, Indrani Talukdar, Sutapa Roy Ramanan, Meenal Kowshik, Self-fluorescence property of octa-arginine functionalized hydroxyapatite nanoparticles aids in studying their intracellular fate in R1 ESCs, Biochemical and Biophysical Research Communications, Volume 627, 2022, Pages 21-29, ISSN 0006-291X, https://doi.org/10.1016/j.bbrc.2022.08.012.

16) Zantye, P., Dahiya, A., Kowshik, M., Ramanan, S. R., & Talukdar, I. (2024). Biocompatible hydroxyapatite‐based nano vehicle bypasses viral transduction and enables sustained silencing of a pluripotency marker gene, demonstrating desired differentiation in mouse embryonic stem cells. The Journal of Gene Medicine26(7), e3716.https://doi.org/10.1002/jgm.3716