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Sanjay Kumar

goa Chemistry

Professor of Practice

Antibody-Drug Conjugates, Bioorganic & Medicinal Chemistry, Drug Discovery & Development, Natural Product Chemistry, Synthetic Organic Chemistry
Chamber # A-206/5
Department of Chemistry
BITS Pilani, K K Birla Goa Campus
sanjaykumar@goa.bits-pilani.ac.in
0832-2580463
https://www.linkedin.com/in/dr-sanjay-kumar-mrsc-4b81a319/

Publications

  1. V H Krishnaprasad and Sanjay Kumar. Antimicrobial Resistance: An Ultimate Challenge for 21st Century Scientists, Healthcare Professionals, and Policymakers to Save Future Generations. Med. Chem. Sept 5, 2024 (https://doi.org/10.1021/acs.jmedchem.4c02002) (Impact Factor 8)
  2. Sanjay Kumar. Innovative Drug Discovery Research by Pharmaceutical Companies in India and China. Med. Chem. 2024, 67, 9773-9775 (Impact factor 8)
  3. Jigar Desai, Bhaumin Patel, Nandini Panchal, Archana Gite, Brijesh Darji, Kasinath, Viswanathan, Jinal Trivedi, Purvi Vyas, Vishwanath Pawar, Poonam Giri, Rajiv Sharma, Mukul Jain, Pravin Iyer & Sanjay Kumar. Discovery of a potent & novel topoisomerase inhibitor with broad spectrum anti-bacterial activity. Med. Che. Lett. May 2024, 111, 129911-17 (Impact factor 2.8)
  4. Jigar Desai, Bhaumin Patel, Archana Gite, Nandini Panchal, Sanjay Gite, Anil Argade, Jeevan Kumar, S Sachchidanand, Debdutta Bandyopadhyay, Krishnarup Ghoshdastidar, Hoshang Patel, Abhijit Chatterjee, Jogeshwar Mahapatra, Manoranjan Sharma, Poonam Giri, Sanjay Kumar, Mukul Jain, Rajiv Sharma, Ranjit Desai. Optimisation of momelotinib with improved potency and efficacy as pan-JAK inhibitor. Med. Chem. Lett. 2022, 16, 128728-128736 (Impact factor 2.8)
  5. Jigar Desai, Sachchidanand S, Sanjay Kumar, Rajiv Sharma. Novel Bacterial topoisomerase inhibitors (NBTIs)- A comprehensive review. European Journal of Medicinal Chemistry Reports, 2021, 3, 100017 (Impact Factor-1.3)
  6. Sanmoy Pathak, Abhijeet Gokhroo, Ashim Kumar Dubey, Shamik Majumdar, Souradeep Gupta, Asha Almeida, Girish B. Mahajan, Abhijeet Kate, Prabhu Mishra, Rajiv Sharma, Sanjay Kumar, Ram Vishwakarma, Arun Balakrishnan, Hanudatta Atreya, Dipankar Nandi . 7-Hydroxy Frullanolide, a sesquiterpene lactone, increases intracellular calcium amounts, lowers CD4+ T cell and macrophage responses, and ameliorates DSS-induced colitis. International Immunopharmacology, 2021, 107655 (Impact factor 5.7)
  7. Jigar Desai, Bhaumin Patel, Brijesh Darji, Archana Gite, Nandini Panchal, Gokul Bhosale, Sandeep Shedage, Sandip Patel, Pravin Kadam, Gautam Patel, Brijesh Kumar Srivastava, Amit Joharapurkar, Samadhan Kshirsagar, Poonam Giri, Hitesh Bhayani, Ankit Patel, Krishnarup Ghoshdastidar, Debdutta Bandyopadhyay, Sanjay Kumar, Mukul Jain, Rajiv Sharma. Discovery of novel, potent and orally efficacious inhibitors of neutral amino acid transporter B0AT1 (SLC6A19). Med. Chem. Lett. 2021, 53, 128421 (Impact factor 2.8)
  8. Vrajesh Pandya, Sanjay Kumar, Sachchidanand, Rajiv Sharma, Ranjit Desai. Combating autoimmune disease with Retinoic acid receptor related orphan receptor-g (RORg or RORc) inhibitors: Hits and misses. J. Med. Chem. 2018, 61(24), 10976-10995 (Impact factor 8)
  9. Archana Jalota-Badhwar; Dimple R. Bhatia; Srinivas Boreddy; Asavari Joshi; Magesh Venkatraman; Nikesh Desai; Sarika Chaudhari; Julie Bose; Lakshmi S. Kolla; Vijaykumar Deore; Nilambari Yewalkar; Sanjay Kumar; Rajiv Sharma; Anagha Damre; Avinash More; Somesh Sharma; Veena R. Agarwal. P7170: A Novel Molecule with Unique Profile of mTORC1/C2 and Activin Receptor-like Kinase 1 Inhibition Leading to Antitumor and Antiangiogenic Activity. Cancer Ther. 2015, 14(5), 1095-1106 (Impact factor 6)
  10. Venkatasubbaiah A Venkatesha, Asavari Joshi, Magesh Venkataraman, Vinay Sonawane, Dimple Bhatia, Prashant Tannu, Julie Bose, Sarika Choudhari, Ankita Srivastava, Prashant Kumar Pandey, Vaibhavi J Lad, Ramachandra Sangana, Tausif Ahmed, Anagha Damre, Vijaykumar Deore, Bichismita Sahu, Sanjay Kumar, Somesh Sharma and Veena R Agarwa. P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer. Molecular Cancer, 2014, 13, 259 (Impact factor 41.4)
  11. Godse P., Kumar P., Yewalkar N., Deore V., Lohar M., Mundada R., Padgaonkar A., Manohar S., Joshi A., Bhatia D., Desai N., Damre A., Bhonde M, Joshi K, Sharma R. and Kumar S. Discovery of P3971 an Orally Efficacious Novel Anticancer Agent Targeting HIF-1N and STAT3 Pathways. Anti-Cancer Agents in Medicinal Chemistry, 2013, 13, 1460-1466 (Impact factor 2.5)
  12. Sharma R. Kumar S., Haldar S. The therapeutic potential of GPR120: a patent review. Expert Opinion On Therapeutic Patents, 2013, 23 (12), 1581-1590 (Impact factor 6.7)
  13. Kumar S, Sharma R, Roychowdhury A. Modulation of Cytochrome-P450 inhibition (CYP) in drug discovery: A medicinal chemistry perspective. Med. Chem. 2012, 19, 3605-3621. (Impact factor 4.1)
  14. Manohar S., Padgaonkar A., Badhwar A.J., Sonawane V., Rathos M.J., Kumar S and Joshi K. A novel inhibitor of hypoxia-inducible factor-1alpha P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells. BMC Cancer, 2011, 11, 338. (Impact factor 4.4)
  15. Vijaykumar Deore, ManojKumar Lohar, Ramswaroop Mundada, Abhijt Roychowdhury, Ram A. Vishwakarma, Sanjay Kumar*. An efficient synthesis of key intermediate towards Liphagal synthesis. Comm. 2011, 41, 177-183 (Impact factor 1.94)
  16. Nilambari Yewalkar, Vijaykumar Deore, Amol Padgaonkar, Sonal Manohar, Bichismita Sahu, Pramod Kumar, Archana Jalota-Badhwar, Kalpana S. Joshi, Somesh Sharma, Sanjay Kumar*. Development of novel inhibitors targeting HIF-1a towards anticancer drug discovery. Med. Chem. Lett. 2010, 20, 6426-6429 (Impact factor 2.8)
  17. Abhijit Roychowdhury, Rajiv Sharma & Sanjay Kumar*. Recent advances in the discovery of small molecule mTOR inhibitors. Future Medicinal 2010, 2 (10), 1577-1589 (Impact factor 4.2)
  18. Nilesh M. Dagia, Gautam Agarwal, Anshu Chetrapal-Kunwar, Divya V. Kamath, Ravindra D. Gupte, Mahesh G. Jadhav, Shruta Dadarkar, Jacqueline Trivedi, Asha A. Kulkarni-Almeida, Firuza Kharas, Sanjay Kumar & Mandar R. Bhonde. A preferential p110a/g A PI3K Inhibitor Attenuates Experimental Inflammation by Suppressing the Production of Pro-Inflammatory Mediators in a NF-kB Dependent Manner. J. Physiology-Cell Physiology, 2010, 298 (4), C929-941 (Impact factor 5.3)
  19. Vijaykumar Deore, Mandar R Bhonde, Ram A Vishwakarma, Nilesh M Dagia, Sanjay Kumar & Abhijit Roychowdhury. “mammalian target of rapamycin (mTOR) inhibitors with therapeutic potential for colitis” Indian J. Chemistry (Sec B), 2009, 48B, 1761-1765 (Impact factor 0.5)
  20. Vijaykumar Deore, Nilambari Yewalkar, Dimple Bhatia, Nikesh Desai, Ravindra D. Gupte, Shruta, S. Dadarkar, Mahesh G. Jadhav, Aditi A. Tannu, Pooja Bhatt, Kumar Nemmani, Ram A. Vishwakarma, Somesh Sharma, Abhijit Roychowdhury, Nilesh M. Dagia, Mandar R. Bhonde and Sanjay Kumar* Synthesis and Therapeutic Evaluation of Pyridyl Based Novel mTOR Inhibitors. Med. Chem. Lett. 2009, 19, 2949-2952. (Impact factor 2.8)
  21. Mandar R. Bonde, Ravindra D. Gupte, Shruta D. Dadarkar, Mahesh G. Jadhav, Aditi A. Tannu, Pooja Bhatt, Dimple R. Bhatia, Nikesh K. Desai, Vijaykumar Deore, Nilambari Yewalkar, Ram A. Vishwakarma, Somesh Sharma, Sanjay Kumar & Nilesh M. Dagia A Novel mTOR Inhibitor is Efficacious in a Murine Model of Colitis, J. Physiology (Gastrointestinal & Liver Physiology), 2008, 295, G1237-G1245. (Impact factor 4.9)
  22. Manoj V. Lohar, Ramswaroop Mundada, Mandar Bhonde, Amol Padgaonkar, Vijaykumar Deore, Nilambari Yewalkar, Dimple Bhatia, Maggie Rathos, Kalpana Joshi, Ram A. Vishwakarma & Sanjay Kumar*; Design and Synthesis of Novel Furoquinoline Based Inhibitors of Multiple Targets in the PI3K/Akt-mTOR Pathway. Med. Chem. Lett. 2008, 18, 3603-3609. (Impact factor 2.8)
  23. Vijaykumar Deore, Manoj V. Lohar, Nilambari Yewalkar, Ramswaroop Mundada, Seema Ranaware & Sanjay Kumar*; Regioselective Synthesis of Quinazoline Containing Novel Monoaryl Ethers at Room Temperature. Het. Chem. 2007, 44, 495-498. (Impact factor 2)
  24. Sanjay Kumar, Gyanendra Kumar, Mili Kapoor, Avadhesha Surolia & Namita Surolia, “Synthesis and evaluation of substituted pyrazoles: Potential antimalarials targeting Enoyl-ACP reductase of Plasmodium Falciparum”. Synthetic Communications, 2006, 36 (2), 215-226. (Impact factor 1.94)
  25. Sanjay Kumar, Abhijit Roychowdury, Brian Ember, Qian Wang, Rongjin Guan, Roy A. Mariuzza & Geert-Jan Boons. “Selective recognition of synthetic Lysine and meso-Diaminopimelic acid-type peptidoglycan fragments by human peptidoglycan recognition proteins Ia & S”. Journal of Biological Chemistry, 2005, 280 (44), 37005-37012. (Impact factor 5.5)
  26. Rongjin Guan, Abhijit Roychowdury, Brian Ember, Sanjay Kumar, Geert-Jan Boons, and Roy A. Mariuzza, “Crystal structure of a peptidoglycan recognition protein (PGRP) in complex with a muramyl tripeptide from garm-positive bacteria”, Endotoxin Research. 2005, 11 (1), 41-46. (Impact factor 3)
  27. Rongjin Guan, Abhijit Roychowdury, Brian Ember, Sanjay Kumar, Geert-Jan Boons, and Roy A. Mariuzza, “Structural basis for peptidoglycan binding by peptidoglycan recognition proteins”, Natl Acad. Sci. U.S.A., 2004, 101 (49), 17168-17173. Sec: Immunology (Impact factor 11)
  28. Sanjay Kumar, Mili Kapoor, Namita Surolia and Avadhesha Surolia, “One step synthesis of novel antimicrobial 2-hydroxy diaryl ethers through domestic microwave heating”, Communication, 2004, 34 (3), 413-420. (Impact factor 1.94)
  29. Shailendra Kumar Sharma, Mili Kapoor, T. N. C. Ramya, Sanjay Kumar, Gyanendra Kumar, Rahul Modak, Shilpi Sharma, Namita Surolia, and Avadhesha Surolia, “Identification, characterization and inhibition of Plasmodium falciparum C-hydroxyacyl-acyl carrier protein dehydratase (FabZ)”, Journal of Biological Chemistry, 2003, 278 (46), 45661-45671. (Impact factor 5.5)
  30. Sanjay Kumar, Vibha Shukla, Arvind Misra, Snehlata Tripathi and Krishna Misra; “New curcumin - bioconjugate: Synthesis and DNA binding”. Indian Journal of Biotechnology 2002, 1(2), 158-163. (Impact factor 0.3)
  31. Krishna K. Dubey, Yashveer Singh, Sanjay Kumar, Ramendra K. Singh and Krishna Misra. “Covalent labeling at 5'-end of synthetic oligonucleotides by one step generation of alkylamino group”. Indian Journal of Chemistry, 2002, 41B(6), 1246-1250. (Impact factor 0.5)
  32. Sanjay Kumar, Upma Narain, Snehlata Tripathi and Krishna Misra, “Synthesis and In Vitro Studies of Curcuminbioconjugates on b-Lactmase Producing Microorganisms”. Bioconjugate Chemistry. 2001, 12(4), 464-469. (Impact factor 6)
  33. Sanjay Kumar, Krishna K. Dubey, Yashveer Singh and Krishna Misra; “New versatile halogenating reagent for hydroxyl groups”. Indian Journal of Chemistry, 2001, 40B(9), 842-845. (Impact factor 0.5)
  34. Sanjay Kumar, Arvind Misra, Snehlata Tripathi, and Krishna Misra, “Study on Curcumin-Oligonucleotide Conjugate as a Probable Anticancer Agent. Its Hybridisation with Telomere Target Sequence 5'-GGG ATT GGG ATT-3'”. Nucleic Acids Symp. Ser. 2001, 137-138.
  35. Sanjay Kumar, Krishna K. Dubey, Snehlata Tripathi, Masayuki Fujii & Krishna Misra, “Design and Synthesis of Curcumin-Bioconjugates to Improve Systemic Delivery”, Nucleic Acids Symp. Ser. 2000, 44, 75-76.

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