Publications after joining BITS

1. Das, U.; Basu, U.; Paira, U.; “Recent Trends in the Design and Delivery Strategies of Ruthenium Complexes for Breast Cancer Therapy” Dalton Trans. 2024 (accepted)

Publications from postdoctoral research

1. Zhou, X.; Abyar, S.; Carbo-Bague, I.; Wang, L.; Türck, S.; Siegler, M.A.; Basu, U.; Ott, I.; Liu, R.; IJzerman, A. P.; Bonnet, S. “Multitarget Thiol-Activated Tetrapyridyl Gold (III) Complexes for Hypoxic Cancer Therapy” CCS Chemistry, 2023, 6, 783–797 [Link]

2. Müller, V.V.L.; Simpson, P.V.; Peng, K.; Basu, U.; Moreth, D.; Nagel, C.; Türck, S.; Oehninger L.; Ott I.; Schatzschneider, U.; “Taming the Biological Activity of Pd(II) and Pt(II) Complexes with Triazolato “Protective” Groups: ¹H, ⁷⁷Se Nuclear Magnetic Resonance and X-ray Crystallographic Model Studies with Selenocysteine to Elucidate Differential Thioredoxin Reductase Inhibition” Inorg. Chem. 2023, 62, 16203-16214 [Link]
3. Kalathil, A. A.^#; Guin, S. ^#; Ashokan, A. ^#; Basu, U. ^#; Surnar, B.; Delma, K. S.; Lima, L. M.; Kryvenko, O. N.; Dhar, S. “New Pathway for Cisplatin Prodrug to Utilize Metabolic Substrate Preference to Overcome Cancer Intrinsic Resistance” ACS Cent. Sci. 2023, 9, 1297−1312 [Link] (^# Equal contribution)

4. Babu, T.; Ghareeb, H.; Basu, U.; Schueffl, H.; Theiner, S.; Heffeter, P.; Koellensperger, G.; Metanis, N.; Gandin, V.; Ott, I.; Schmidt, C.; Gibson “Oral Anticancer Heterobimetallic Pt^IV−Au^I Complexes Show High In Vivo Activity and Low Toxicity” Angew. Chem. Int. Ed. 2023, e202217233 [Link]
5. Gil-Moles, M.; Türck, S.; Basu, U.; Pettenuzo, A.; Ott, I. and others “Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the Spike/ACE2 interaction and the Papain-like Protease PLpro” Chem. Eur. J., 2021, 27, 17928-17940. [Link]
6. Khodjoyan, S.; Remadna, E.; Dossmann, H.; Lesage, D.; Gontard, G.; Forte, J.; Hoffmeister, H.; Basu, U.;Ott, I.; Spence, P.; Waller, Z. A. E.; Salmain, M.; Bertrand, B. “[(CC)Au(NN)]+ complexes as a new family of anticancer candidates:   synthesis, characterization and exploration of the antiproliferative properties” Chem. Eur. J., 2021, 27, 15573-15785. [Link]
7. Schmidt, C; Babu, T; Kostrhunova, H; Timm, A; Basu, U;Ott, I; Gandin, V; Brabec, V; Gibson, D. “Are Pt (IV) Prodrugs That Release Combretastatin A4 True Multi-action Prodrugs?” Med. Chem.,2021, 64, 11364–11378.[Link]
8. Zhou, X.; Carbo-Bague, I.; Siegler, M. A.; Hilgendorf, J.; Basu, U.;Ott, I.; Liu, R.; Zhang, L.; Ramu, V.; IJzerman, A. P.; Bonnet, S. “Rollover Cyclometalation vs Nitrogen Coordination in Tetrapyridyl Anticancer Gold(III) Complexes: Effect on Protein Interaction and Toxicity” JACS Au 2021, 1, 380–395. [Link]
9. Basu, U.;Roy, M.; Chakravarty, A.R. “Recent Advances in the Chemistry of Iron-based Chemotherapeutic Agents” Coord. Chem. Rev. 2020, 417, 213339 [Link]
10. Gil-Moles, M.;Basu, U.; Büssing, R.; Hoffmeister, H.; Türck, S.; Varchmin, A.; Ott, I. “Gold Metallodrugs to Fight the Corona Virus: Inhibitory Effects on the Spike ACE2 Interaction and on PLpro Protease Activity by Auranofin and Gold Organometallics” Chem. Eur. J. 2020, 26, 15140-15144. [Link]
11. Bhattacharya, S.;Basu, U.; Haouas, M.; Su, P.; Espenship, M. F.; Wang, F.; Solé-Daura, A.; Taffa, D. H.; Wark, M.; Poblet, J. M.; Laskin, J.; Cadot, E.; Kortz, U. “Discovery of neutral palladium-oxo clusters Pd₁₆ and Pd₂₄ and their supramolecular interactions” Angew. Chem. Int. Ed. 2020, 60, 3632-3639. [Link]
12. Notaro, A.; Frei, A; Rubbiani, R.; Jakubaszek, M.; Basu, U.; Koch, S.; Mari, C.; Dotou, M.; Blacque, O.; Gouyon, J.; Bedioui, F.; Rotthowe, N.; Winter, R.; Goud, B.; Ferrari, S.; Tharaud, M.; Rezácová, M.; Humajová, J.; Tomšík, P.; Gasser, G. “A Ruthenium(II) Complex Containing a Redox-Active Semiquinonate Ligand as Potential Chemotherapeutic Agent: From Synthesis to In VivoStudies" Med. Chem. 2020,63,5568–5584. [Link]
13. Ortega, E.; Zamora, A.; Basu, U.; Lippmann, P.; Rodríguez, V.; Janiak, C.; Ott, I.; Ruiz “An Erlotinib gold (I) conjugate for combating triple-negative breast cancer” J. Inorg. Biochem.2020, 203, 110910 [Link]
14. Cheng, X.; Haeberle, S.; Shytaj, I. L.; Gama-Brambila, R.A; Theobald, J.; Ghafoory, S.; Wölker, J.; Basu, U.; Schmidt, C.; Timm, A.; Taškova, K.; Bauer, A.S; Hoheisel, J.; Tsopoulidis, N.; Fackler, O.T; Savarino, A.; Andrade-Navarro, M.A; Ott, I.; Lusic, M.; Hadaschik, E.N.; Wölfl, S. “NHC-gold compounds mediate immune suppression through induction of AHR-TGFβ1 signalling in vitro and in scurfy mice” Commun. Biol. 2020, 3, 1-12. [Link]
15. Walther, W.; Althagafi, D.; Curran, D.; O’Beirne, C.; Mc Carthy, C.; Ott, I.;Basu, U.; Büttner, B.; Sterner-Kock, A.; Müller-Bunz, H.; Sanchez-Sanz, G.; Zhu, X.; Tacke, M. “In-vitro and in-vivo investigations into the carbene-gold anticancer drug candidates NHC*-Au-SCSNMe₂ and NHC*-Au-S- GLUC against advanced prostate cancer PC3” Anti-Cancer Drugs 2020, 31, 672-683. [Link]
16. Karges, J.; Basu, U;Blaque, O.; Chao, H.; Gasser, G. “Polymeric Encapsulation of Novel Homoleptic Bis(dipyrrinato) Zinc(II) Complexes with Long Lifetimes for Applications as Photodynamic Therapy Photosensitizers” Angew. Chem. Int. Ed. 2019, 58, 14334-14340. [Link]
17. Basu, U.;Otto, S.; Heinze, K.; Gasser, G. “Biological Evaluation of the NIR-Emissive Ruby Analogue [Cr(ddpd)₂][BF₄]₃ as a Photodynamic Therapy Photosensitizer” Eur. J. Inorg. Chem. 2019, 37-41. [Link]
18. Basu, U.;Karges, J.; Chotard, F.; Balan, C.; Le Gendre, P.; Gasser, G.; Bodio, E.; Kabbara, R. M. “Investigation of photo-activation on ruthenium (II)–arene complexes for the discovery of potential selective cytotoxic agents” Polyhedron 2019, 172, 22-27. [Link]
19. Surnar, B.; Kamran, M.Z.; Shah, A.; Basu, U.;Kolishetti, N.; Deo, S.; Jayaweera, D. T; Daunert, S.; Dhar, S. “Orally Administrable Therapeutic Synthetic Nanoparticle for Zika Virus” ACS Nano 2019, 13, 11034-11048. [Link]
20. Surnar, B.;^# Basu, U.; ^# Banik, B.; Ahmad, A.; Marples, B.; Dhar, S. “Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection” Proc. Natl. Acad. Sci. USA 2018, 115, (^# Equal contribution) [Link]
21. Pathak, R. K.;^#Basu, U.;^# Ahmad, A.; Kumar, A.; Ansari, S.; Kolishetti, N.; Wilczek, K.; Ivan, M.; Marples, B.; Dhar, S. “A designer bow-tie combination therapeutic platform: An approach to resistant cancer treatment by simultaneous delivery of cytotoxic and anti-inflammatory agents and radiation” Biomaterials 2018, 187, 117-129 (^# Equal contribution) [Link]
22. Surnar, B.; Kolishetti, N.; Basu, U.;Ahmad, A.; Goka, E.; Marples, B.; Kolb, D.; Lippman, M.; Dhar, S. “Reduction of Cisplatin-Induced Ototoxicity without Compromising Its Antitumor Activity” Biochemistry 2018, 57, 6500-6513. [Link]
23. Basu, U.; Banik, B.; Wen, R.; Pathak, R. K.; Dhar, S. “The Platin-X series: activation, targeting, and delivery” Dalton Trans. 2016, 45, 12992-13004. [Link]

Publications from PhD research

1. Sahoo, S.; Podder, S.; Garai, A.; Majumdar, S.; Mukherjee, N.; Basu, U.;Nandi, D.; Chakravarty, A. R. “Iron(III) Complexes of Vitamin B₆ Schiff Base with Boron-Dipyrromethene Pendants for Lysosome-Selective Photocytotoxicity” Eur. J. Inorg. Chem 2018, 13, 1522-1532. [Link]

2. Basu, U.;Pant, I.; Kondaiah, P.; Chakravarty, A. R. “Mitochondria-Targeting Iron (III) Catecholates for Photoactivated Anticancer Activity under Red Light” Eur. J. Inorg. Chem. 2016, 1002-1012. [Link]

3. Raza, M.K.; Mitra, K.; Shettar, A.   Basu, U.; Kondaiah, P.; Chakravarty, A. R. “Photoactive platinum (ii) β-diketonates as dual action anticancer agents”Dalton Trans. 2016, 45,13234-13243. [Link]

4.  Basu, U.; Pant, I.; Hussain, A.; Kondaih, P.; Chakravarty, A. R. “Iron (III) complexes of a pyridoxal Schiff base for enhanced cellular uptake with selectivity and remarkable photocytotoxicity” Inorg. Chem. 2015, 54, 3748-3758. [Link]

5. Garai, A.; Basu, U.;Pant, I.; Kondaiah, P.; Chakravarty,  R. “Polypyridyl iron (II) complexes showing remarkable photocytotoxicity in visible light” J. Chem. Sci.2015, 127, 609-618. [Link]
6. Basu, U.; Khan, I.; Hussain, A.; Gole, B.; Kondaiah, P.; Chakravarty, A. R. “Carbohydrate-appended tumor targeting iron (III) complexes showing photocytotoxicity in red light” Inorg. Chem. 2014, 53, 2152-2162. [Link]

7. Basu, U.; Pant, I.; Khan, I.; Hussain, A.; Kondaiah, P.; Chakravarty, A. R. “Iron (III) catecholates for cellular imaging and photocytotoxicity in red light” Chem. Asian J. 2014, 9, 2494-2504. [Link]

8. Mitra, K.; Basu, U.; Khan, I.; Maity, B.; Kondaiah, P.; Chakravarty A. R. “Remarkable anticancer activity of ferrocenyl-terpyridine platinum (II) complexes in visible light with low dark toxicity” Dalton Trans. 2014, 43, 751-763. [Link]

9. Garai, A.; Basu, U.; Khan, I.; Hussain, A.; Pant, I.; Kondaiah, P.; Chakravarty, R. “Iron (III) benzhydroxamates of dipicolylamines for photocytotoxicity in red light and cellular imaging” Polyhedron 2014, 73, 124-132. (Cover Article) [Link]

10. Basu, U.; Khan, I.; Hussain, A.; Kondaiah, P.; Chakravarty, A. R. “Photodynamic Effect in Near-IR Light by a Photocytotoxic Iron (III) Cellular Imaging Agent” Angew. Chem. Int. Ed. 2012, 51, 2658-2661. (VIP Article) [Link]

11. Basu, U.;Khan, I.; Koley, D.; Saha, S.; Kondaiah, P.; Chakravarty, A. R. “Nuclear targeting terpyridine iron (II) complexes for cellular imaging and remarkable photocytotoxicity” J. Inorg. Biochem. 2012, 116, 77-87. [Link]