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Utpal Roy

Professor

Antimicrobial drug discovery and Rapid detections of pathogens, Bioprospecting
Professor Utpal Roy, Department of Biological Sciences, BITS Pilani-K.K. Birla Goa Campus, NH 17B bypass Road, PIN- 403726

PhD and M.E Research Supervision.

Ph.D. thesis student Supervision – Doctoral (Ph.D.) Degree: Supervised Nine Ph.D. students and 3 ongoing

Sl.No.

Name of Student

Year of Completion

Title of  Ph.D. Theses

1.

Swetha Ramesh

2024

“Characterization of Novel Antifungal Lipopeptides Against Candida albicans And Non-albicans Strains and Elucidation of Their Mode Of Action”

2.

REHAN A. DESHMUKH

Degree Awarded 2020

Development of Rapid and Sensitive Molecular Methods for the Detection and Quantification of Escherichia coli in water

3.

GAUTAM K.

Degree Awarded 2019

Functional Characterization of Recombinant α-Crystallin of Mycobacterium tuberculosis H37Rv

4.

AJAY G. CHALASANI

Degree Awarded 2018

Biochemical and Functional Characterization of a Narrow-Spectrum Antibacterial Peptide from the Wild-type Bacillus sp.

5.

RAMYA R

Degree awarded’2018

She has been declared as one of the winners of the YOUNG INTERNATIONAL SOCIETY for HUMAN & ANIMAL MYCOLOGY’ Grant for the 20th ISHAM Congress going to be held at Amsterdam’ July’ 2018.

6.

PURNIMA SINGH

Deg. Awarded in Nov, 2016

Studies on Microbial Diversity and Biotechnological Potential of Selected Polar Organisms;

Awarded prestigious Indo-US Science and Technology Forum (IUSSTF) Fellowship in August 2017.

7.

RAEESH  SHEKH

Aug’ 2013 (Degree awarded.

Study on Biochemical and Genetic Characterization of anti-Candida Substance Produced by Enterococcus faecalis.

8.

VEEKY BATHS

Aug’ 2012 (Degree awarded)

  Systems Biology and Graph Theoretic Approaches to Identify Potential Drug Targets against Mycobacterium tuberculosis.

9.

SUBODH K SRIVASTAVA

2009 (degree awarded)

Single Nucleotide Polymorphisms in Granule Bound Starch Synthase-I gene & its association with starch quality in Rice genotypes

10

Madhuri Madduri

Likely to submit thesis 2024-2025

SERB-sponsored JRF (Thesis work in progress)

11.

Pritish R. Shukla

4.3 yrs

Birla Carbon-CSR

11.

Sreelakshmi K.P.

2nd year

DBT-Builder

M.E. Dissertation/Thesis student Research Supervision.

Sl.No.

Name of Student

Year of Completion

M.E. (Biotechnology) Dissertation/Thesis

1.

ANVIKSHA S

May 2019 (Degree awarded)

Exploration on the functional characterization of antifungal lipopeptide fractions isolated from B. subtilis

2.

KANIKA  BHATNAGAR

May 2015 (degree awarded

Optimization of the production parameters of the antifungal substance by Bacillus species and its partial purification.

3.

RIYAZ BASHA

NOV, 2012 (degree awarded)

PCR based Species level Identification of Malaria Parasite and genetic analysis of drug resistance markers in P. falciparum isolates.

4.

AKHILESH DIXIT

MAY, 2010 (degree awarded)

Preliminary Biochemical Characterization and Optimization of Production of the Antimicrobial Substance Produced by a Selected wild-type bacterial isolate.

 

Research Support: Completed and Ongoing Research Projects details

Sl. No.

Title of Project

Funding Agency

SANCTIONED Amount (Lacs)

Date of start and Duration

1.

In vitro and in vivo Evaluation of The Functionally-characterized Broad-spectrum Antifungal Cyclic Lipopeptides… against Medically Important Mucorales

Indian Council of Medical Research

 95.50 Lacs

30th March 2024 ongoing

2.

Recovery of Resources from Worn-out Tires for Enabling Circular Economy (Co-PI)

Birla Carbon

50.0 Lacs

2021-2025 (ongoing)

3.

Development of Prototype Biosensor for detection of bacteria (E. coli/ Shigella and Salmonella spp.) in drinking

BITS BioCyth

40 Lacs

2022- ongoing

4.

Unlocking the Potential of Green Cosmetic Nanoemulsions for Targeted Acne Vulgaris Therapy: Advanced Modeling and Optimization Strategies”    

CDRF

15 Lacs

2023- Ongoing

5.

Evaluation of Antifungal activity of Lipopeptides from a Wild- type Bacillus sp. RLID 12.1 in Mouse Models of Invasive Candidiasis, Cryptococcosis, and Aspergillosis’-Joint project with PGIMER

SERB

Total sanctioned amt 65.3 Lakhs approx.

Start date: 23rd December’ 2018 for 3 yrs.

6.

Exploration of Antifungal Lead Molecules from the Wild-type Bacillus subtilis & molecular characterization along with optimizing production (Principal Investigator & Project Coordinator);

Co-PI: Department of Medical Microbiology, PGIMER, Chandigarh

Joint project with PGIMER

DBT

48.69

 3 yrs. (01/02/2017)

End Date: 30th June 2020

7.

Microbial Diversity & Biotechnological Potentials of some Polar Organisms [MENTOR & Supervisor]

DST-WOS

20.79

2014-2017 (Completed in March 2017)

8.

Purification & Characterization of Antimicrobial Compound with special reference to C. albicans and C. neoformans [Principal Investigator];

Co-PI: Dr. A. Chakrabarti, PGIMER, Chandigarh

SERB

10.69

2015-16 (Completed in March 2016)

9.

Screening, Isolation and Identification of Novel Antimicrobial Compounds from Potential Mangroves of Goa (CO-Investigator)

CSIR

20.0

2016-2019, would end on August 2019.

10.

 Study on EMT regulation through TGFβ/SMADs in gall bladder disease[Co-PI]

DST

37.0 lacs

2014-2017, Completed

11.

“Development of a Field-deployable Biosensor for Bacterial sensing in potable water” WWEM-Water Core Project [Co-PI]

BITS University

40.65

May 2014-March 2017, completed

 

Research Projects Completed

Sl No.

Title of Project

Funding Agency

Amount

Date of completion

1.

Cloning and expression of goat Interleukin 1 (Co-investigator)

BITS PILANI

2.00 Lacs

2001-2003, Completed

2.

DST-FIST  (Coordinator)

DST

41.0

2015,Completed

3.

“Isolation & screening of microorganism from extreme & unusual environment for new & novel antimicrobial peptides to combat some clinically important multi-drug resistant fungal pathogens” (PI)

CSIR, New Delhi

17.00 lacs

(approx.)

Completed, 31st March, 2011,

4.

Biochemical & genetic characterization of Candidacidal peptides produced by the strain E. faecalis APR- 210. (PI)

UGC, N Delhi

7.34  lacs

Completed, February, 2014, 3yrs

5.

Screening of extremophile isolates  for novel antimicrobial substances against selected multi-drug resistant human pathogens (PI)

DST, N Delhi

11.38  Lacs

Completed, March 2011, 18 months,

6.

Studies on extremophilic isolates for novel antimicrobial substances: biochemical and genetic characterization of Antimicrobial substance produced by a selected wild-type extremophile isolate against multi-drug resistant clinical isolates (as Mentor)

DST-WOS

14.92 Lacs

Completed  December 2012

Govt Agency-sponsored Fellowship/Financial support/Travel grants to Ph.D. students enlisted below

 

PhD students

Name of the Govt. fellowship/funding agency

Year of Award

PhD awarded/

submitted/ongoing

Supervisor

/Mentor

1.

KP Sreelakshmi

DBT-Builder

2023

             Ongoing

Utpal Roy

2.

Pritish R Shukla

PMRF, BIRLA CARBON

2023

Ongoing

Utpal Roy

3.

Swetha R

ICMR-SRF

2022

Ongoing

 

Utpal Roy

 

4.

Madhuri M

SERB-JRF

2018

Ongoing

 

5.

Swetha R

DBT Project-SRF

2017

 

 

6.

Purnima S

Indo-US Science and Technology Forum (IUSSTF) Fellowship

 

2017

Awarded

 

Utpal Roy

 

7.

Rehan Deshmukh

ICMR-SRF

2018

Awarded

 

Utpal Roy

 

8.

Ramya R

20th ISHAM Grant

2018

Awarded

 

 

9.

Ramya R

CSIR-SRF

2015

 

 

10.

Purnima S

ICMR Travel grant

2016

Awarded

 

Utpal Roy

 

11.

Purnima S

DST-WOS

2015

 

 

12.

Ramya R

DBT-travel grant

2012

 

 

13.

Ramya R

DST-Project JRF

2011

 

 

14.

Ajay G. Chalasani

UGC-JRF

2011

Awarded

 

Utpal Roy

 

15

Raeesh Shekh

CSIR-SRF

2011

Awarded

 

 

16

Purnima S

DST-WOS

2010

 

 

16

Md. Raeesh Shekh

CSIR-project JRF

2007

 

 

Utpal Roy

 

17

Subodh Srivastava

CSIR-SRF

2006

Awarded

 

Utpal Roy