Sl. No.

Publications

2024

176

A Structure-Based Design Strategy with Pyrazole-Pyridine Derivatives Targeting TNFα as Anti-inflammatory Agents: E-pharmacophore, Dynamic Simulation, Synthesis and In Vitro Evaluation, Debojyoti Halder, Jeyaprakash R S, Balaram Ghosh*, Chemistry and Biodiversity, [IF: 2.9]

175

Tocopherol-HSA Nanoparticles Enhance Lapatinib Delivery and Overcoming Doxorubicin Resistance in Breast Cancer: Milan Paul, Sneha Das, Balaram Ghosh, Swati Biswas, Nanomedicine. [IF: 5.5] [Accepted]

174

Biotinylated platinum(IV)-Conjugated Graphene Oxide Nanoparticles for Targeted Chemo-Photothermal Combination Therapy in Breast Cancer: Asif Itoo Mhod, Milan Paul, Balaram Ghosh, Swati Biswas, Biomaterials Advances. [IF: 7.9]

173

Exploring the impact of trifluoromethyl (-CF3) functional group on the anti-cancer activity of isoxazole-based molecules: Design, synthesis, biological evaluation and molecular docking analysis, Paramita Pattanayak, Sripathi Nikhitha, Debojyoti Halder, Balaram Ghosh*, Tanmay Chatterjee*, RSC Advances, doi.org/10.1039/D4RA02856B, [IF: 3.9].

172

Biphenylsulfonamides as effective MMP-2 inhibitors with promising antileukemic efficacy: Synthesis, in vitro biological evaluation, molecular docking, and MD simulation analysis: Sandip Kumar Baidya, Tarun Patel, Ambati Himaja, Suvankar Banerjee, Sanjib Das, Balaram Ghosh*, Tarun Jha* Nilanjan Adhikari, Drug development and research.

171

Synthesis and antiproliferative potency of 1,3,4-thiadiazole and 1,3-thiazolidine-4-one based new binary heterocyclic molecules: in vitro cell-based anticancer studies: Avik Maji, Ambati Himaja, Sripathi Nikhitha, Soumitra Rana, Abhik Paul, Ajeya Samanta, Chhanda Mukhopadhyay, Balaram Ghosh *, Tapan Kumar Maity. RSC Medicinal Chemistry. [IF: 4.1] [Accepted]

170

Derivatives of D(-) glutamine-based MMP-2 inhibitors as an effective remedy for the management of chronic myeloid leukemia-Part-I: Synthesis, biological screening and in silico binding interaction analysis: Sanjib Das, Subha Mondal, Tarun Patel, Ambati Himaja, Nilanjan Adhikari, Suvankar Banerjee, Sandip Kumar Baidya, Asit Kumar De, Shovanlal Gayen, Balaram Ghosh*,Tarun Jha, European Journal of Medicinal Chemistry, 238 (2022) 114470, doi.org/10.1016/j.ejmech.2024.116563, [IF: 6]

169

Ferulic acid-g-tamarind gum/guar gum based in situ gel-forming powders as wound dressings, Akash Mondal, Suman Barai, Hriday Bera, Tarun Patel, Nanda Gopal Sahoo, Darakhshan Begum, Balaram Ghosh, International Journal of Biological Macromolecules. [IF: 7.7]

168

F127/Chlorin e6-nanomicelles to Enhance Ce6 Solubility and PDT-efficacy Mitigating Lung Metastasis in Melanoma, Milan Paul, Balaram Ghosh and Swati Biswas. Accepted Drug Delivery and Translational Research. [IF: 5.4]

167

Exploring different classification-dependent QSAR modeling strategies for HDAC3 inhibitors in search of meaningful structural contributors, Tarun Jha, Rahul Jana, Suvankar Banerjee, Sandip Kumar Baidya, Sk. Abdul Amin, Shovanlal Gayen, Balaram Ghosh, and Nilanjan Adhikari: SAR and QSAR in Environmental Research. doi.org/10.1080/1062936X.2024.2350504. [IF: 3.0]

166

Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration, Xuezhao Liu, Dazhuan Eric Xin, Xiaowen Zhong, Chuntao Zhao, Zhidan Li, Liguo Zhang, Adam J. Dourson, Lindsay Lee, Shreya Mishra, Arman E. Bayat, Eva Nicholson, William L. Seibel, Bingfang Yan, Joel Mason, Bradley J. Turner, David G Gonsalvez, William Ong, Sing Yian Chew, Balaram Ghosh, Sung Ok Yoon, Mei Xin, Zhigang He, Jason Tchieu, Michael Wegner, Klaus-Armin Nave, Robin J. M. Franklin, Ranjan Dutta, Bruce D. Trapp, Ming Hu, Matthew A. Smith, Michael P. Jankowski, Samantha K Barton, Xuelian He, and Q. Richard Lu*, Cell, (2024), https://doi.org/10.1016/j.cell.2024.04.005, [IF: 64.5].

165

Pharmacological blockade of HDAC6 attenuates cancer progression by inhibiting IL-1β and modulating immunosuppressive response in OSCC: Ashutosh Mahale, Routholla Ganesh, Pravesh Sharma, Balaram Ghosh, Onkar P Kulkarni, International Immunopharmacology, 132, 111921, (2024), https://doi.org/10.1016/j.intimp.2024.111921, [IF: 5.6].

164

Fragment-based discovery of new potential DNMT1 inhibitors integrating multiple pharmacophore modeling, 3D-QSAR, virtual screening, molecular docking, ADME, and molecular dynamics simulation approaches: Goverdhan Lanka, Suvankar Banerjee, Nilanjan Adhikari, Balaram Ghosh*, Molecular Diversity, (2024), doi.org/10.1007/s11030-024-10837-5, [IF: 3.8].

163

Pharmacophore modeling, 3D-QSAR, and MD-simulations-based overture for the discovery of new potential HDAC1 inhibitors: Goverdhan Lanka, Sanjeev Regula, Suvankar Banerjee, Nilanjan Adhikari, Balaram Ghosh*, Journal of Biomolecular Structure & Dynamics (Accepted), (2024)[IF: 4.4]

162

Exploring crucial structural attributes of quinolinyl methoxyphenyl sulphonyl-based hydroxamate derivatives as ADAM17 inhibitors through classification-dependent molecular modelling approaches: Tuhin Baran Samoi, Suvankar Banerjee, Balaram Ghosh, Tarun Jha, Nilanjan, SAR and QSAR in Environmental Research, 35(2), 157–179, (2024) https://doi.org/10.1080/1062936X.2024.2311689, [IF: 3.0].

161

161. Recent Advancements in Nanotechnology-Mediated Platinum-Based Cancer Therapy, Asif Itoo,  Balaram Ghosh, Swati Biswas, Coordination Chemistry Reviews, 508, 215796, (2024) doi.org/10.1016/j.ccr.2024.215796, [IF: 20.6].

160

Glycol chitosan-poly (lactic acid) (1:1) conjugate nanoparticles encapsulating ciprofloxacin: A mucoadhesive anti-quorum-sensing biofilm-disrupting treatment modality for bacterial keratitis, Sri Ganga Padaga, Himanshu Narendrakumar Bhatt, Sanjay Ch, Milan Paul, Asif Itoo, Balaram Ghosh, Sanhita Roy, Swati Biswas, ACS Appl. Mater. Interfaces, 16, 15, 18360–18385, (2024), doi.org/10.1021/acsami.3c18061, [IF: 9.5].

159

Discerning prime contributors of quinazoline-derivatives conveying HDAC6 inhibition: An in silico structural and binding pattern analysis, Suvankar Banerjee, Sandeep Jana, Tarun Jha, Balaram Ghosh, Nilanjan Adhikari. Computational Biology and Chemistry, 110, 108051, (2024) https://doi.org/10.1016/j.compbiolchem.2024.108051, [IF: 3.1].

158

Development of biotin decorated Olaparib loaded cationic lipopolymeric hybrid nanoparticle and evaluation of its anticancer effect and pharmacokinetics for triple negative breast cancer, Rajesh Pradhan, Shobha Kumari, Himaja Ambati, Tarun Kumar Patel, Balaram Ghosh, Anu Puri, Sunil Kumar Dubey, Rajeev Taliyan, Journal of Drug Delivery Science and Technology, 94, 105458, (2024), https://doi.org/10.1016/j.jddst.2024.105458, [IF:5.0].

157

Discovery of Thiazolidinedione-based pancreatic lipase inhibitors as anti-obesity agents: Synthesis, In silico studies and Pharmacological investigations: Prashant Dhiman, Nisha Yadav, Prashant S. Auti, Shalini Jaswal, Gurpreet Singh, Sidharth Mehan, Balaram Ghosh, Atish T. Paul, Vikramdeep Monga, Journal of Biomolecular Structure & Dynamics, (2024), https://doi.org/10.1080/07391102.2024.2310799, [IF: 4.4].

156

Sulfide Induced Concentration Dependent Distinct Optical Response: Unique Chromogenic Probe Developed for Analyzing Fecal contamination in Water and Intracellular Imaging Applications: Rikitha S Fernandes, Sanjay Ch, Balaram Ghosh*, Nilanjan Dey, ACS Sustainable Chemistry & Engineering, 12, 12, 4922–4932, (2024), https://doi.org/10.1021/acssuschemeng.3c07719, [IF: 8.4].

155

3D-Printed Inherently Antibacterial Contact Lens-like Patches Carrying Antimicrobial Peptide Payload for Treating Bacterial Keratitis, Sanjay Ch, Priyasha Mishra, Sri Ganga Padaga, Balaram Ghosh, Sanhita Roy, Swati Biswas, Macromolecular Biosciences, 24, 4, (2024), https://doi.org/10.1002/mabi.202300418, [IF: 4.5].

154

Chitosan Oligosaccharide Lactate-Pluronic F127 Micelles/Gatifloxacin with Anti-Biofilm Anti-Quorum Sensing Activity to Treat Bacterial Keratitis: Sri Ganga Padaga, Sanjay Ch, Milan Paul, Bhavika Deepak Wable, Balaram Ghosh, Swati Biswas, Carbohydrate Polymers, 330, 121818, (2024), https://doi.org/10.1016/j.carbpol.2024.121818, [IF: 11.2].

153

Cationized Gelatin-Sodium Alginate Polyelectrolyte Nanoparticles Encapsulating Moxifloxacin as an Eye Drop to Treat Bacterial Keratitis: Sanjay Ch, Sri Ganga Padaga, Milan Paul, Balaram Ghosh, and Swati Biswas. 264(1), 130457, International Journal of Biological Macromolecules, 264(1), 130457, (2024), https://doi.org/10.1016/j.ijbiomac.2024.130457, [IF: 8.2].

152

Significance of TRAIL/Apo-2 ligand and its death receptors in apoptosis and necroptosis signalling: Implications for cancer-targeted therapeutics, Avik Maji, Abhik Paul, Arnab Sarkar, Sourin Nahar, Rudranil Bhowmik, Ajeya Samanta, Pankaj Nahata, Balaram Ghosh*, Sanmoy Karmakar, Tapan Kumar Maity, Biochemical Pharmacology, 221, 116441, (2024), https://doi.org/10.1016/j.bcp.2024.116041, [IF:5.8].

151

Human Serum Albumin-Oxaliplatin (Pt(IV)) Prodrug Nanoparticles with dual reduction sensitivity as  Effective Nanomedicine for Triple-Negative Breast Cancer: Milan Paul, Balaram Ghosh, Swati Biswas, International Journal of Biological Macromolecules, 256(1), (2024), https://doi.org/10.1016/j.ijbiomac.2023.128281 [IF: 8.2]

150

Fragment-based investigation of thiourea derivatives as VEGFR-2 inhibitors: A cross-validated approach of ligand-based and structure-based molecular modeling studies: Suvankar Banerjee, Shristi Kejriwal, Balaram Ghosh, Goverdhan Lanka, Tarun Jha, Nilanjan Adhikari: Accepted in Journal of Biomolecular Structure & Dynamics, 42, 2, 1047–1063, (2024), https://doi.org/10.1080/07391102.2023.2198039, [IF: 4.4].

149

Exploring structural requirements of sulfonyl pyrrolidine derivatives as promising MMP-2 inhibitors through validated robust multi-QSAR modeling analysis and binding mode of interactions: Journal of Biomolecular Structure & Dynamics, (2024), Accepted, [IF: 4.4] .

148

Chapter 6 - Micelles-based drug delivery for pancreatic cancer, Sanjay Ch, Tarun Kumar Patel, Swati Biswas, Balaram Ghosh, Recent advances in Nanocarriers for Pancreatic Cancer Therapy, (2024). Pages. 115-144.

2023

147

Synergistic Anticancer Response via Docetaxel and Oleanolic Acid-Loaded Albumin/Poly(lactide) Nanoparticles in Triple-Negative Breast Cancer: Sneha Das; Milan Paul; Balaram Ghosh; Swati Biswas. ACS Applied Nano Materials, 6, 21, 19710–19726, (2023), https://doi.org/10.1021/acsanm.3c03499, [IF: 5.9].

146

Pharmacophore-based virtual screening, 3D QSAR, Docking, ADMET, and MD simulation studies: An in silico perspective for the identification of new HDAC3 potential inhibitors, Goverdhan Lanka, Darakhshan Begum, Suvankar Banerjee, Nilanjan Adhikari, Yogeeswari P, Balaram Ghosh*, Computers in Biology and Medicine, 166, 107481, (2023), doi.org/10.1016/j.compbiomed.2023.107481, [IF: 7.7].

145

Selective HDAC3 Inhibitors with Potent In Vivo Antitumor Efficacy against Triple-Negative Breast Cancer, Sravani Pulya, Ambati Himaja, Milan Paul, Nilanjan Adhikari, Suvankar Banerjee, Ganesh Routholla, Swati Biswas, Tarun Jha, and Balaram Ghosh*, Journal of Medicinal Chemistry, 66, 17, 12033–12058, (2023), https://doi.org/10.1021/acs.jmedchem.3c00614, [IF: 7.3].

144

Fragment-based structural exploration and chemico-biological interaction study of HDAC3 inhibitors through non-linear pattern recognition, chemical space, and binding mode of interaction analysis: Suvankar Banerjee, Shraddha Dumawat, Tarun Jha, Goverdhan Lanka, Nilanjan Adhikari, Balaram Ghosh*, Journal of Biomolecular Structure & Dynamics, (2023), https://doi.org/10.1080/07391102.2023.2248509, [IF: 4.4].

143

Histone Deacetylase 8 as an Emerging Target in Drug Discovery with Special Emphasis on Medicinal Chemistry: Srinidhi Rajaraman, Ranjani Balakrishnan, Dhruv Deshmukh, Abhiram Ganorkar, Swati Biswas, Sravani Pulya, Balaram Ghosh*, Future Med Chem,15, 10, (2023), https://doi.org/10.4155/fmc-2023-0054, [IF: 4.2].

142

Pharmacological blockade of HDAC3 accelerates diabetic wound healing by regulating macrophage activation, Kalyani Karnam, Kavitha Sedmaki, Pravesh Sharma, Balaram Ghosh, Onkar Prakash Kulkarni, Life Sciences, 321, 121574, (2023), https://doi.org/10.1016/j.lfs.2023.121574, [IF: 6.1].

141

Hydrazides as potential HDAC inhibitors: Structure-activity relationships and biological implications: Suvankar Banerjee, Sandip Kumar Baidya, Nilanjan Adhikari, Tarun Jha, Balaram Ghosh*, Current Topics in Medicinal Chemistry, 23, 25, (2023), http://dx.doi.org/10.2174/1568026623666230405124207, [IF: 3.4].

140

140. Chapter 23 - Epigenetics of Memory Processes: Sravani Pulya, Balaram Ghosh*: Editor(s): Trygve O. Tollefsbol, Handbook of Epigenetics (Third Edition), Academic Press, 2023, Pages 443-464, ISBN 9780323919098, doi.org/10.1016/B978-0-323-91909-8.00018-9.

139

A combined ligand-based and structure-based in silico molecular modeling approach to pinpoint the key structural attributes of hydroxamate derivatives as promising meprin β inhibitors: Sandeep Jana, Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh, Tarun Jha, Nilanjan Adhikari, Journal of Biomolecular Structure & Dynamics, (2023), [IF: 4.4].

138

Advances in the Delivery and Development of Epigenetic Therapeutics for the Treatment of Cancer: Aparajita Ghosh, Ambati Himaja, Swati Biswas, Onkar Kulkarni, Balaram Ghosh*, Molecular Pharmaceutics (ACS), 20, 12, 5981–6009, (2023), https://doi.org/10.1021/acs.molpharmaceut.3c00610, [IF: 4.9].

137

Identification of potential antiviral lead inhibitors against SARS-CoV-2 main protease: Structure-guided virtual screening, docking, ADME, and MD Simulation based approach, Goverdhan Lanka, Revanth Bathula, Balaram Ghosh, Sarita Rajender Potlapally, Artificial Intelligence Chemistry, 1(2), (2023), https://doi.org/10.1016/j.aichem.2023.100015.

136

A fragment-based exploration of diverse MMP-9 inhibitors through classification-dependent structural assessment, Sandip Kumar Baidya, Suvankar Banerjee, Balaram Ghosh, Tarun Jha, Nilanjan Adhikari,  Journal of Molecular Graphics and Modelling, 126, 108671, (2023),  https://doi.org/10.1016/j.jmgm.2023.108671, [IF: 2.9].

135

Assessing structural insights into in-house arylsulfonyl L-(+) glutamine MMP-2 inhibitors as promising anticancer agents through structure-based computational modeling approaches: Sandip Kumar Baidya, Suvankar Banerjee, Balaram Ghosh, Tarun Jha, Nilanjan Adhikari,  SAR and QSAR in Environmental Research, (2023), 34, 10, 805–830 https://doi.org/10.1080/1062936X.2023.2261842, [IF: 3.0].

134

Current Trends in the Development of Liposomes for Chemotherapeutic Drug Delivery: Soniya Kumbham, Srinivas Ajjarapu, Balaram Ghosh, Swati Biswas, Journal of Drug Delivery Science and Technology, 86, 104854, (2023), https://doi.org/10.1016/j.jddst.2023.104854 [IF:5.0].

133

Employing comparative QSAR techniques for the recognition of dibenzofuran and dibenzothiophene derivatives toward MMP-12 Inhibition: Jigme Sangay Dorjay Tamang, Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh, Nilanjan Adhikaria and Tarun Jha, Journal of Biomolecular Structure & Dynamics, (2023), https://doi.org/10.1080/07391102.2023.2239923, [IF: 4.4].

132

Polymeric Graphene Oxide Nanoparticles Loaded with Doxorubicin for Combined Photothermal and Chemotherapy in Triple Negative Breast Cancer, Asif Mohd Itoo, Milan Paul, Balaram Ghosh, Swati Biswas, Biomaterials Advances, 153, 213550, (2023) https://doi.org/10.1016/j.bioadv.2023.213550 [Cite score: 17.3].

131

Concurrent Delivery of Paclitaxel and Chlorin e6 to Tumors Using Albumin/PLGA Nanoparticles for NIR-Light Triggered Chemo-Photodynamic Therapy, Milan Paul, Himanshu Bhatt, Soniya Kumbham, Balaram Ghosh, Swati Biswas, ACS Applied Nano Materials, 6, 14, 13385–13399, (2023), https://doi.org/10.1021/acsanm.3c02056, [IF: 5.9].

130

In vitro Antioxidant and Cytotoxic Potential of Pleurotus Mushroom and Activity-Based Correlation: a Comparative Study: Singh Shreya, Debadatta Mohapatra, Gaurav Gopal Naik, Yamini Bobde, Balaram Ghosh, and Alakh N Sahu: Journal of Analytical Chemistry, 78 (4), 456–463. (2023), https://doi.org/10.1134/S1061934823040135, [IF: 1.1].

129

Exploration of structural alerts and fingerprints for novel anticancer therapeutics: A robust classification-QSAR dependent structural analysis of drug-like MMP-9 inhibitors: Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh, Tarun Jha, Nilanjan Adhikari, SAR and QSAR in Environmental Research, 34, 4, 299–319, (2023) https://doi.org/10.1080/1062936X.2023.2209737, [IF: 3.0].

128

Chitosan-poly(lactide-co-glycolide)/Poloxamer mixed micelles as a mucoadhesive thermo-responsive moxifloxacin eye drop to improve treatment efficacy in bacterial keratitis, Sanjay Ch, Sri Ganga Padaga, Balaram Ghosh, Sanhita Roy, Swati Biswas, Carbohydrate Polymers, 312, 120822, (2023), https://doi.org/10.1016/j.carbpol.2023.120822 [IF: 11.2].

127

The Quality by Design approach of slayer exciter based Low Power Portable Atmospheric Plasma jet on bactericidal efficacy of Pseudomonas Aeruginosa: P.N. Sidhartha, Sanjay Ch, Balaram Ghosh*, Karumbaiah N Chappanda, Journal of Biophotonics, https://doi.org/10.1002/jbio.202200333, [IF: 2.8].

126

Quantitative Structural Assessments of Potential Meprin β Inhibitors by Non-linear QSAR Approaches and Validation by Binding Mode of Interaction Analysis, Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh, Suvendu Nandi, Mahitosh Mandal, Tarun Jha, Nilanjan Adhikari, New Journal of Chemistry, 47, 7051-7069, 2023, https://doi.org/10.1039/D2NJ04753E,[IF: 3.3].

125

Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In-Vitro and In-Vivo Assessment: Manami Dhibar, Santanu Chakraborty, Souvik Basak, Paramita Pattanayak, Tanmay Chatterjee, Balaram Ghosh, and Mohammad A.S. Abourehab, Pharmaceuticals, 16(2), 284, (2023), https://doi.org/10.3390/ph16020284, [IF:4.6].

124

Block HPMA-based pH-sensitive Gemcitabine Pro-drug Nanoaggregate for Cancer Treatment: Tarun Patel, Asif Mohd Itoo, Milan Paul, Likhitha Purna Kondapaneni, Balaram Ghosh*, Swati Biswas. European Polymer Journal, 186, 15, 111843, (2023), doi.org/10.1016/j.eurpolymj.2023.111843 (IF: 6).

123

Hypoxia alleviating platinum(IV)/chlorin e6-based combination chemotherapeutic-photodynamic nanomedicine for oropharyngeal carcinoma, Milan Paul, Asif Mohd Itoo, Balaram Ghosh, Swati Biswas. Journal of Photochemistry and Photobiology B: Biology, 238, 112627, (2023) doi.org/10.1016/j.jphotobiol.2022.112627, [IF: 5.4]

122

Glycyrrhizin as a promising kryptonite against SARS-CoV-2: Clinical, experimental, and theoretical evidences, Suvankar Banerjee, Sandip Kumar Baidya, Nilanjan Adhikari, Balaram Ghosh*, Tarun Jha, Journal of Molecular Structure, 1275, 134642, (2023), doi.org/10.1016/j.molstruc.2022.134642. [IF: 3.8].

2022

121

Selective Inhibition of Histone deacetylase 3 by Novel Hydrazide Based Small Molecules as Therapeutic Intervention for the Treatment of Cancer, Sravani Pulya, Tarun Patel, Milan Paul, Nilanjan Adhikari, Suvankar Banerjee, Ganesh Routholla, Swati Biswas, Tarun Jha, Balaram Ghosh*, European Journal of Medicinal Chemistry, 238, 114470, (2022),  doi.org/10.1016/j.ejmech.2022.114470. [IF: 6.7].

120

HDAC6 inhibition attenuates renal injury by reducing IL-1β secretion and RIP kinase mediated necroptosis in acute oxalate nephropathy, Kavitha Sedmaki; Kalyani Karnam; Pravesh Sharma; Ashutosh Mahale; Ganesh Routholla, Balaram Ghosh; Onkar Kulkarni, International Immunopharmacology, 110, 108919, (2022), doi.org/10.1016/j.intimp.2022.108919, [IF: 5.6].

119

Nanotherapeutic Intervention in Photodynamic Therapy for Cancer, Asif Itoo, Milan Paul, Sri Ganga Padaga, Balaram Ghosh, Swati Biswas, ACS Omega, 7, 50, 45882–45909, (2022), doi.org/10.1021/acsomega.2c05852, [IF: 4.1].

118

Synthesis and appraisal of dalbergin-loaded PLGA nanoparticles modified with galactose against hepatocellular carcinoma: in-vitro, pharmacokinetic, and in-silico studies: Anurag Kumar Gautam, Pranesh Kumar, Biswanath Maity, Ganesh Routholla, Balaram Ghosh, P.S. Rajinikanth, Sanjay Singh, Sudipta Saha, Vijayakumar M.R, Frontiers in Pharmacology: Section Pharmacology of Anti-Cancer Drugs, 13, 1021867, (2022), doi: 10.3389/fphar.2022.1021867 [IF: 5.6].

117

Current trends in the use of human serum albumin for drug delivery in cancer, Milan Paul, Asif Itoo, Balaram Ghosh, Swati Biswas, Expert Opinion on Drug Delivery, 19:11, 1449-1470, (2022), doi: 10.1080/17425247.2022.2134341, [IF: 6.6].

116

Human Serum Albumin-Poly(Lactide)-Conjugated Self-Assembly NPs for Targeted DTX Delivery and Improved Therapeutic Efficacy in Oral Cancer, Soniya Kumbham, Adrija Ghosh, Balaram Ghosh, Swati Biswas, International Journal of Biological Macromolecules, 222, A, 1287-1303, (2022), doi.org/10.1016/j.ijbiomac.2022.09.250, [IF:8.2].

115

Multifunctional Graphene Oxide Nanoparticles for Drug Delivery in Cancer, Asif Mohd Itoo, Sree Lakshmi Vemula, Mahima Tejasvni Gupta, Mahesh Vilasrao Giram, Sangishetty Akhil Kumar, Balaram Ghosh, Swati Biswas. Journal of Controlled Release, 350, 2022, 26-59, doi.org/10.1016/j.jconrel.2022.08.011, [IF: 10.8].

114

Olaparib@human serum albumin nanoparticles as sustained drug-releasing tumor-targeting nanomedicine to inhibit growth and metastasis in the mouse model of triple-negative breast cancer, Nageswara Rao Vysyaraju; Milan Paul, Sanjay Ch, Balaram Ghosh, Swati Biswas, Journal of Drug Targeting, 30:10, 1088-1105, (2022), https://doi.org/10.1080/1061186X.2022.2092623[IF: 4.5].

113

First Report on Predictive Comparative Ligand-based Multi-QSAR Modeling Analysis of 4-pyrimidinone and 2-pyridinone based APJ inhibitors: Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh, Nilanjan Adhikari, Tarun Jha, New Journal of Chemistry., 46, 11591-11607, (2022), https://doi.org/10.1039/d2nj01923j, [IF: 3.3].

112

Estrogenicity of Tetrazole Bisphenols: Computational studies, Synthesis and Invitro assessment: Gadgoli, Umesh; Y.C, Sunil; Kumar, Deepak; Pai, Maya; Pulya, Sravani; Ghosh, Balaram; Kulkarni, Onkar, Journal of Chemical Information and Modeling (ACS): 62(4), 854-873, (2022), https://doi.org/10.1021/acs.jcim.1c01077. [IF: 6.162].

111

Oleanolic Acid-conjugated human serum albumin nanoparticles encapsulating doxorubicin as synergistic combination chemotherapy in oropharyngeal carcinoma and melanoma: Kumbham, Soniya; Paul, Milan; Itoo, Asif; Ghosh, Balaram; Biswas, Swati.: International Journal of Pharmaceutics, 614, 121479, (2022), doi.org/10.1016/j.ijpharm.2022.121479.  [IF: 6.510].

110

Oxaliplatin delivery via chitosan/vitamin E conjugate-based supramolecular nanoassembly for improving therapeutic efficacy and overcoming drug resistance in breast cancer: Asif Mohd Itoo; Milan Paul; Balaram Ghosh, Swati Biswas: Carbohydrate Polymers, 282, 119108, (2022), doi.org/10.1016/j.carbpol.2022.119108, [IF: 11.2].

109

Design, Synthesis and SAR Studies of Novel Spirochromanone hydrochloride Analogues as Anticancer Agents, Surendar Chitti#, Sravani Pulya#, Adinarayana Nandikolla, Tarun Kumar Patel, Banoth Karan Kumar, Sankaranarayanan Murugesan, Balaram Ghosh*, KVG Chandra Sekhar, Future Medicinal Chemistry, 14 (5), 325-342, 2022, doi.org/10.4155/fmc-2021-0237, [IF: 4.2].

108

Ligand-based quantitative structural assessments of SARS-CoV-2 3CLpro inhibitors: An analysis in light of structure-based multi-molecular modeling evidences: Nilanjan Adhikari, Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh*, Tarun Jha, Journal of Molecular Structure, 1251, 132041, (2022), doi.og/10.1016/j.molstruc.2021.132041, [IF: 3.8].

2021

107

Design, Synthesis and Binding Mode of Interaction of Novel Small Molecule o-Hydroxy Benzamides as HDAC3-Selective Inhibitors with Promising Antitumor Effects in 4T1-Luc Breast Cancer Xenograft Model, Ganesh Routholla, Sravani Pulya, Tarun Patel, Nilanjan Adhikari, Sk. Abdul Amin, Milan Paul, Srividya Bhagavatula, Swati Biswas, Tarun Jha, Balaram Ghosh*,  Bioorganic Chemistry, 117 105446, (2021), doi.org/10.1016/j.bioorg.2021.105446, [IF: 5.1].

106

Quantitative activity-activity relationship (QAAR) driven design to develop hydroxamate derivatives of pentanoic acids as selective HDAC8 inhibitors, Synthesis, biological evaluation and binding mode of interaction studies: Sk. Abdul Amin, Prakruti Trivedi, Nilanjan Adhikari, Routholla Ganesh, Dhanya Vijayasarathi, Sanjib Das, Balaram Ghosh*, Tarun Jha, New Journal of Chemistry, 45(37), 17149-17162, (2021), doi.org/10.1039/DINJ02636D, [IF: 3.3].

105

Dissecting Histone Deacetylase 3 in Multiple Disease Conditions: Selective Inhibition as a Promising Therapeutic Strategy: Nilanjan Adhikari, Tarun Jha, Balaram Ghosh*. JMC (Journal of Medicinal Chemistry, ACS), 64(13):8827-8869, (2021), doi.org/10.1021/acs.jmedchem.0c1676 [IF: 7.446].

104

Synthesis, Biological Evaluation, and Molecular Docking Analysis of Novel Linker-less Benzamide Based Potent and Selective HDAC3 Inhibitors, Ganesh Routholla, Sravani Pulya, Tarun Kumar Patel, Sk. Abdul Amin, Nilanjan Adhikari, Swati Biswas, Tarun Jha, Balaram Ghosh*. Bioorganic Chemistry, 114, 105050, (2021), doi.org/10.1016/j.bioorg2021105050, [IF: 5.1].

103

Small Molecule Drug Conjugate (SMSC): Am Emerging Target for Anticancer Drug Design and Discovery: Tarun Kumar Patel, Nilanjan Adhikari, Sk. Abdul Amin, Swati Biswas, Tarun Jha, Balaram Ghosh*, New Journal of Chemistry, (2021), doi.org/10.1039/d0nj04134c [IF: 3.3].

102

PT3: A novel benzamide class histone deacetylase 3 inhibitor Improves Learning and Memory in Novel Object Recognition Mouse Model, Pulya, Sravani; Mahale, Ashutosh; Bobde, Yamini; Routholla, Ganesh; Patel, Tarun Kumar; Singh, Swati; Biswas, Swati; Sharma, Vivek; Kulkarni, Onkar; Ghosh, Balaram*, ACS Chemical Neuroscience, 12, 5, 883–892, (2021), https://doi.org/10.1021/acschemneuro.0c00721, [IF: 5.0].

101

HDAC6 as privileged target in drug discovery: A perspective, Sravani Pulya, Sk. Abdul Amin, Nilanjan Adhikari, Swati Biswas, Tarun Jha, Balaram Ghosh*, Pharmacological Research, 163, 105274, (2021), doi: org/10.1016/j.phrs.2020.105274, [IF: 9.3].

100

Hydroxypropyl methacrylamide-based copolymeric nanoparticles loaded with moxifloxacin as a mucoadhesive, cornea-penetrating nanomedicine eye drop with enhanced therapeutic benefits in bacterial keratitis: Sanjay Ch, Priyasha Mishra, Himanshu Bhatt, Balaram Ghosh, Sanhita Roy, Swati Biswas, Colloids and Surfaces B: Biointerfaces, 208, 112113, 2021, doi.org/10.1016/j.colsurfb.2021.112113, [IF: 5.8].

99

Design and Development of Distinct Tetracyanoquinodimethane Derivatives Exhibiting Dual Effect of Fluorescence and Anticancer Activity: Anwarhussaini Syed Himabindu Battula, Yamini Bobde, Tarun Patel, Balaram Ghosh, Subbalakshmi Jayanty: ChemistrySelect, 6, 7354 – 7366, (2021), doi: org/10.1002/slct.202101721, [IF: 2.1].

98

Enhanced floating and intra gastric release of 5-Flourouracil through sesame oil entrapped gellan composite hydrogel beads: Madhumita Dey, Balaram Ghosh, Tapan Giri. Current Drug Therapy, 16(3), 242-252, (2021), doi: 10.2174/1574885516666210521120620. [IF: 0.6].

97

Polymeric micelles of a copolymer composed of all-trans-retinoic acid, methoxy-poly(ethylene glycol), and b-poly(N-(2 hydroxypropyl) methacrylamide) as a doxorubicin-delivery platform and for combination chemotherapy in breast cancer, Yamini Bobde, Milan Paul, Tarun Patel, Swati Biswas, Balaram Ghosh*, International Journal of Pharmaceutics, 606, 120866, 2021, doi.org/10.1016/j.ijpharm.2021.120866, [IF: 5.8].

96

PEGylated N-(2 hydroxypropyl) methacrylamide based polymeric micelles for the delivery of Doxorubicin in breast cancer, Yamini Bobde, Tarun Patel, Milan Paul, Swati Biswas, Balaram Ghosh*, Colloids and Surfaces B: Biointerface, 204, 111833, (2021),  doi.org/10.1016/j.colsurfb.2021.111833. [IF: 5.8].

95

Robust classification-based molecular modeling of diverse chemical entities as potential SARS-CoV-2 3CLpro inhibitors: Theoretical justification in light of experimental evidences: Nilanjan Adhikari, Suvankar Banerjee, Sandip Kumar Baidya, Balaram Ghosh*, Tarun Jha, SAR and QSAR in Environmental Research, doi.org/10.1080/1062936X.2021.1914721, [IF: 3.000]

94

Design, synthesis and biological evaluation of 7–(5–((amino)methyl) thiophen–2–yl) spiro[chroman–2,4'–piperidin]–4–one hydrochloride analogues as anti-tumor agents,  Surendar Chitti#, Sravani Pulya#, Adinarayana Nandikolla, Tarun Kumar Patel, Banoth Karan Kumar, Murugesan Sankaranarayanan, Balaram Ghosh*, KVG Chandra Sekhar, Bioorganic Chemistry, 112 (2021) 104865, doi.org/10.1016/j.bioorg.2021.104865. [IF: 5.1]

93

Distinct rhodamine B derivatives exhibiting dual effect of anticancer activity and fluorescence property: Himabindu Battula, Sivaganesh Bommi, Yamini Bobde, Tarun Patel, Balaram Ghosh*, Subbalakshmi Jayanty, Journal of Photochemistry and Photobiology, 6, 100026, (2021), doi.org/10.1016/j.jpap.2021.100026

92

Targeted Bioimaging of Cancer Cells Using Free Folic Acid-Sensitive Molybdenum Disulfide Quantum Dots through Fluorescence “Turn-off”, Susmita Roy­, Yamini Bobde, Balaram Ghosh* and Chanchal Chakraborty, ACS Applied Bio Materials, 4, 3, 2839-2849, (2021), doi.org/10.1021/acsabm.1c00090. [IF: 4.7].

91

Polymeric Micelles in Cancer Therapy: State of the Art; Balaram Ghosh and Swati Biswas. Journal of Controlled Release, 332, 127–147, (2021), https://doi.org/10.1016/j.jconrel.2021.02.016, [IF: 10.8].

2020

90

HDAC6 inhibitor accelerates wound healing by inhibiting tubulin mediated IL-1β secretion in diabetic mice: Kalyani Chowdary Karnam, Kavitha Sedmaki, Pravesh Sharma, Ganesh Routholla, Sriharshini Goli, Balaram Ghosh, Venkata Vamsi Krishna Venuganti, Onkar Prakash Kulkarni: Biochimica et Biophysica Acta (BBA)- Molecular Basis of Disease 1866, 11, (2020)165903: doi.org/10.1016/j.bbadis.2020.165903 [IF: 4.352].

89

Design, Synthesis, and Biological Evaluation of Novel Nicotinamide Derivatives as Potential Selective Histone Deacetylase-3 Inhibitors. Mohamed M.S. Hamoud#, Sravani Pulya#, Nermine A. Osman, Yamini Bobde, Abdalla E. A. Hassan, Hanan A. Abdel-Fattah, Balaram Ghosh* Amany M. Ghanim: New Journal of Chemistry 2020, 44 (23), 9671. DOI: 10.1039/d0nj01274b, [IF: 3.925].

88

Lipid-conjugated self-assembled human serum albumin nanoparticles for improved delivery and anticancer activity of loaded curcumin for targeted cancer treatment: Kumari, Preeti; Paul, Milan; Bobde, Yamini; Kumbham, Soniya; Rompicharla, Sri Vishnu Kiran ; Ghosh, Balaram; Biswas, Swati; Nanomedicine-London, 2020 15(29), 2851-2869; doi: 10.2217/nnm-2020-0232.  [IF: 5.307].

87

Oleanolic acid-conjugated poly (D, L-lactide)-based micelles for effective delivery of doxorubicin and combination chemotherapy in oral cancer: Soniya Kumbham; Milan Paul; Himanshu Bhatt; Balaram Ghosh, Swati Biswas. Journal of Molecular Liquids 320 (2020) 114389, 20 Sept. 2020, doi.org/10.1016/j.molliq.2020.114389. [IF: 6.165]

86

Current trends in the development of HPMA-based block co-polymeric nanoparticles for their application in drug delivery: Yamini Bobde, Swati Biswas, Balaram Ghosh*. European Polymer Journal 139 (2020) 110018 doi: org/10.1016/j.eurpolymj.2020. [IF: 4.598].

85

Enhanced intestinal stability and pH sensitive release of quercetin in GIT through gellan gum hydrogels: Madhumita Dey, Balaram Ghosh, Tapan Giri: Colloids Surf B Biointerfaces. 2020 Aug 28; 196:111341. doi.org/10.1016/j.colsurfb.2020.111341, [IF: 5.268].

84

Cell penetrating peptide anchored α-tocopherol conjugated Poly (amidoamine) Dendrimers for enhanced tumor targeting: Himanshu Bhatt, Balaram Ghosh and Swati Biswas. ACS Appl. Bio Mater. 2020, 3, 5, 3157–3169; doi.org/10.1021/acsabm.0c00179, [IF: 4.7].

83

6-chloro, 6,7-dichloro and 2-methyl-3-(((1-(substituted-phenyl)-1H-1,2,3-triazol-4-yl)methoxy)carbonyl)quinoxaline-1,4-dioxide derivatives as anti-tubercular agents: Singireddi Srinivasarao, Adinarayana Nandikolla, Amaroju Suresh, Napiórkowska Agnieszka, Augustynowicz-Kopec Ewa, Balaram Ghosh, Sankaranarayanan Murugesan, Sravani Pulya, Himanshu Aggarwa and Kondapalli Venkata Gowri Chandra Sekhar, Bioorganic Chemistry, 100 (2020) 103955; doi.org/10.1016/j.bioorg.2020.103955) [IF: 5.1]

82

Seeking potent anti-tubercular agents: Design and synthesis of subsituted-N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperzine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agents: Srinivasarao, Singireddi; Nandikolla, Adinarayana; Amaroju, Suresh; Calster, Kevin Van ; Voogt, Linda De ; Kappoen, Davie; Ghosh, Balaram;  Aggarwal, Himanshu; Sankaranarayanan, Murugesan; Chandrasekhar, K.: RSC Advances, 2020, 10, 12272 - 12288 doi: 10.1039/d0ra01348j [IF: 3.9].

81

PEGylated N-(2 hydroxypropyl) methacrylate-Doxorubicin conjugate as pH-responsive polymeric nano-assembly for cancer treatment: Yamini Bobde, Swati Biswas, Balaram Ghosh*. Reactive and Functional Polymers 151 (2020) 104561. doi.org/10.1016/j.reactfunctpolym.2020.104561 [IF: 3.975].

80

Chlorin e6 conjugated methoxy-poly(ethylene glycol)-poly(D,L-lactide) glutathione sensitive micelles for photodynamic therapy: Preeti Kumari, Milan Paul, Himanshu Bhatt, Sri Vishnu Kiran Rompicharla, Debolina Sarkar, Balaram Ghosh, Swati Biswas: Pharm Research 2020 Jan 2;37(2):18. doi: 10.1007/s11095-019-2750-0, [IF: 4.200].

79

Structure activity relationship of Human Carbonic Anhydrase II inhibitors: Detailed Insight for future development as anti-glaucoma agents: Soumajit Ghorai, Partha sarathi Panda, Sravani Pulya, Balaram Ghosh*, Shovanlal Gayen: Bioorganic Chemistry, 95, 10355795 (2020), doi.org/10.1016/j.bioorg.2019.103557, [IF: 5.1].

78

Development and characterization of solid dispersion system for enhancing the solubility and cytotoxicity of dietary capsaicin: Samit Bera; Subhasis Maity, Balaram Ghosh, Animesh Ghosh, Tapan Kumar Giri:  Current Drug Therapy, 15 (2), 143-151, (2020), doi.org/10.2174/1574885514666190724143351, [IF: 0.6].