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Prof. Venkateswaran Rajagopalan

Associate Professor,
Department of Electrical and Electronics Engineering

Biomedical signal /image processing, Graph Theory, Machine Learning, Neurodegenerative Diseases, Neuroimaging MRI and PET
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Research Interest

Neurological Disorders: 
Amyotrophic Lateral Sclerosis (ALS),Multiple Sclerosis (MS), Stroke, Traumatic Brain Injury (TBI), Spinal cord Injury (SCI), Brain Tumor 

Neuroimaging: Structural MRI, functional MRI, Diffusion MRI, PET,  

Electrophysiology: EEG, Transcranial Magnetic Stimulation (TMS), EMG, Functional Electrical Stimulation (FES)

Other Research Areas: Biomechanics, Human Gait Analysis, Machine Learning, Neural Networks, Graph Theory (Brain Network Analysis)

Skills and Expertise: Diffusion MRI single shell, multi shell, Conventional MRI T1-w, T2-w, T2 relaxometry, Voxel Based Morphometry, Tensor Based Spatial statistics, cortical thickness analysis, TMS, EEG, EMG data processing, Tractography, Fractal analysis (mono and multi-fractal), ICA

 Neuroimaging Softwares: FSL, SPM, DTI studio, Freesurfer, DSI studio, ExploreDTI, GAT, EEG Lab

 

Neuroimaging Research in Amyotrophic Lateral Sclerosis (ALS)

Understanding brain network in ALS phenotypes a) ALS patients with corticospinal tract hyperintensity in T2/Pd-W images, b) ALS patients without CST hyperintensity in T2/PD-W images, c) Classic ALS, d) ALS with frontotemporal lobe dementia (ALS-FTD),  

 

Recent Studies

1. Graph theory based MRI analysis of ALS patients

Study

Frontal and temporal white matter (WM) network damage in ALS-FTD patients found using graph theory

 

Graph theory network analysis provides brain MRI evidence of a partial continuum of neurodegeneration in patients with UMN-predominant ALS and ALS-FTD

Differing patterns of cortical gray matter pathology identified by multifractal analysis in UMN predominant ALS phenotypes

Ongoing Studies in ALS
 
Diffusion Network model of disease propagation in ALS phenotypes (completed, manuscript in Preparation)
Free water analysis