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Prof. Balaram Ghosh 

Associate Professor
Department of Pharmacy

Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Sponsored Projects:

 

Sl. No.

Funding Agent

Title of the Project

Amount (Rs)

Role

Status

Ongoing Projects

28

Scheme for Promotion of Academic & Research Collaboration (SPARC)

Prof. Swati Biswas (PI)

Prof. Adam Mechler (La Trobe, Australia)

Prof. Jimmy Hsia (NTU, Singapore).

Formulation-based strategy to design membrane targeting antimicrobial peptide-based therapeutics for cancer and eye infections

Rs. 71.16 Lakhs

Co-PI

Recommended (01, April 2024) (2 years)

27

Department of Biotechnology (DBT) under Joint DBT-NMPB, Ministry of AYUSH Call for Proposals on Biotech Interventions in Medicinal Plants

[Dr. Vidya Rajesh, Dept of Biology and Dr. Onkar Kulkarni, Dept of Pharmacy]

Molecular Studies on Bacopa monnieri to evaluate the modulation of neuronal receptors for schizophrenia using cell based and mouse models: Submitted on January 30_2020

Rs. 30 Lakhs

Co-PI

May 2024 to April 2027 (3 years)

26

Hetero Lab Limited, R&D

Jeedimetla, Hyderabad, Telangana – 500037

India. [Dr. Swati Biswas]

 

Human serum albumin –based nanoparticles as an
antiproteosome therapy for the treatment of advanced
metastatic triple negative breast cancer

Rs. 5.0 Lakhs

Joint PI

Sanctioned

2024-2027 (3 years)

25

Department of Biotechnology (DBT), Govt. of India.

[Dr. Swati Biswas, Dept. of Pharmacy]

3D-Bioprinted Contact Lens Embedding Host-Defense Peptide S100A12 as Precision Medicine for Bacterial Keratitis

 

39.10 Lakhs

Co-PI

Sanctioned (1.5 years)

24

Indian Council of Medical Research (ICMR), Govt. of India

[Dr. Swati Biswas, Dept of Pharmacy]

Revolutionizing Phototherapy with Hypoxia-Reversing Photothermal/ Photodynamic Nanoparticles-Laden In Situ Gel for Non-Invasive Tumor Ablation in Oral Cancer

 

53.13 Lakhs

 

Co-PI

Sanctioned (3 years)

23

Indian Council of Medical Research (ICMR), Govt. of India

[Dr. Swati Biswas, Dept. of Pharmacy]

Antibacterial Nanozyme-Laden in situ Light-Responsive Hydrogel for Tissue Regeneration and Quorum-Sensing Inhibition to Revert Antimicrobial Resistance in Diabetic Foot Ulcers

48.02 Lakhs

 

Co-PI

Sanctioned (3 years)

22

Scheme for Transformational and Advanced Research in Sciences (STARS) for promoting translational, India-centric research in Sciences, to be implemented and managed by Indian Institute of Science (IISc), Bangalore

[Dr. Swati Biswas, Dept of Pharmacy and Dr. Sayan Das, Dept. of  Mech. Engg]

Carbon dioxide-fueled Janus Motors for Targeted Delivery of Therapeutic Cargo in Helicobacter pylori Infection

 

43.15 Lakhs

 

Co-PI

Sanctioned

Jan 2024 (3 years)

21

Indian Council of Medical Research (ICMR), Govt. of India. (Proposal ID: IIRP-2023-5411)

[Dr. Chanchal Chakraborty, Dept. of Chemistry]

Development of Self-Powered Electrochromic Smart Display for Visual Detection of Folate Receptor Overexpressed Cancer Cells

Rs. 41 Lakhs

Co-PI

Sanctioned

Feb 1, 2024 (3 years)

20

Department of Science and Technology, Government of India (CRG-SERB) File Number: CRG/2023/003045

[Dr. Tanmay Chatterjee, Dept. of Chemistry]

Electrochemical green synthesis of medicinally potential organo-chalcogenides and chalcogenoxides and evaluation of their anti-cancer activities in search of novel anti-cancer agents

Rs. 43.486Lakhs

Co-PI

Jan 19, 2024 ( 3 years)

19

Indian Council of Medical Research (ICMR), Govt. of India

Development of epigenetic modulators as therapeutics for cognitive deficit associated with psychosis using novel selective histone deacetylase-3 inhibitors

34.84 Lakhs

PI

Ongoing 25.03.2023 – 24.03.2026 (3 years)

18

Indian Council of Medical Research (ICMR), Govt. of India

[Dr. Onkar Kulkarni, Dept. od Pharmacy]

HDAC3 and its functional role in the progression of cognitive deficits as a secondary complication to chronic kidney disease.

31.16 Lakhs

Co-PI

Ongoing; 01.03.2023 to 28.02.2026 (3 years)

17

Indian Council of Medical Research (ICMR), Govt. of India

{DR. Swati Biswas, Dept of Pharmacy]

Tailor-made, Tumor-Targeted Vitaprotein Nanoparticles of Lapatinib and Letrozole as NanoChemo-Cocktail. for Hormone-Receptor-Amplified Advanced Metastatic Breast Cancers Treatment.

28.82 Lakhs

Co-PI

Ongoing; 27.01.2023 – 26.01.20226 (3 Yrs)

16

Indian Council of Medical Research (ICMR), Govt. of India

[Dr. Nilanjan Dey, Dept. of Chemistry]

Design and development of portable acidosis kit for the rapid, trace-level detection of Ketone bodies in biological samples

34.366 Lakhs (Co-PI: Rs. 6 Lakhs)

Co-PI

 

Ongoing; 01.04.2023– 31.03.2026 (3 Yrs)

15

Department of Health Research (DHR-ICMR).  Government of India

Development of Epigenome Targeted Therapeutics with Improved Selectivity and Drug-ability for the Treatment of Cancer

30.483 Lakhs

PI

Ongoing (15.12.2021 – 14.12.2024; ( 3 Years))

14

DBT-BUILDER (Boost to University Interdisciplinary Life Science Departments for Education and Research).  Government of India

Interdisciplinary Life Science Programme for Advanced Research and Education

300 Lakhs

PI

Ongoing (22.07.

2021 – 21.07.2026 [5 years]

13

Council of Scientific and Industrial Research (CSIR), Government of India

[Dr. Tanmay Chatterjee, Chemistry Dept]

Development of Cost-effective, Electrophilic Trifluoromethylating Reagents and Their Application to the Syntheses of New Classes of Medicinally Potential Trifluoromethylated Heterocycles

25 Lakhs

Co-PI

Ongoing (01.04.2021 – Ongoing 31.03.2024 (3 Yrs)

Completed Projects

12

BITS-Pilani Hyderabad Campus

Validation of therapeutic activity in preclinical models

20 Lakhs

PI

Jan 2023 to Dec 2023

11

Council of Scientific and Industrial Research (CSIR) Government of India

Bifunctional Gene-Expression Modulating Chemotherapeutic Agents as Improved Treatment Strategy for Cancer

26.06 Lakhs

PI

Completed( 2019-2022)

10

Department of Science and Technology, Government of India (SERB-DST)

Near-Infrared Light Degradable Nanomicellar Chemo-Photodynamic Therapy using Aerobic Chlorin e6 Conjugate for Oropharyngeal Carcinomas

30.72

Co-PI

Completed (2019-2022)

9

Indian Council of Medical Research (ICMR), Govt. of India

Functional role of histone deacetylase 6 (HDAC6) in the progression of oral squamous cell carcinoma: regulation of IL-1 beta expression, autophagy and epithelial-mesenchymal –transition (EMT)

26 Lakhs

Co-PI

 

Completed(9.9.2019-8.9.2022)

8

Dr. Reddy’s Laboratory (DRL), Hyderabad

Formulation development and physico-chemical/in vitro/in vivo characterization of a nano-suspension formulation of an anticancer drug.

8.01 Lakhs

PI

Completed (2018-2022)

7

Department of Science and Technology, Government of India (SERB-DST)

Design, Synthesis and Biological Evaluation of HDAC3 Selective Inhibitors as Long Term Memory Enhancers

29.87 Lakhs

PI

Completed (28.08.2017-27.08.2021

6

SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (SPARC), India

Chemically modified epigenome targeted anticancer drug development

29 Lakhs

PI

Completed (2016-2018)

5

Daewoong Pharmaceuticals, Seoul, Republic of Korea

Development for sustained release injectable formulations

22 Lakhs

PI

Completed (2015-2017)

4

Department of Biotechnology (DBT), Government of India

Cell penetrating peptide octa-arginine anchored, multifunctional poly(amidoamine) dendrimer to promote delivery of chemotherapeutics in cancer

37 Lakhs

Co-PI

Completed (2014-2017)

3

Additional Competitive Research Grant: Birla Institute of Technology and Science-Pilani

Design and Development of Isoform Selective HDAC3 Inhibitors for the Enhancement of Long-term Memory

9 Lakhs

PI

Completed (2015-2017)

2

Department of Science and Technology (DST), Government of India (Indo-Belarus joint proposal).

Tumor targeted nanomedicines for photodynamic therapy

10 Lakhs

Co-PI

Completed (2015-2017)

1

Research Initiation Grant: Birla Institute of Technology and Science-Pilani at Hyderabad Campus

Development of Cognitive Enhancers that Inhibit Histone Deacetylase Activity and Modulate Chromatin-mediated Neuroplasticity

2 Lakhs

PI

Completed (2013-2015)

 

Sponsored Project for SRF Fellowship:

Sl. No.

Student

Funding Agent

Years

Status

Role

Amount (Rs.)

1

Prakruti Trivedi

CSIR-SRF

2017-2019

Completed

PI

10,81,600

2

Sravani Pulya

CSIR-SRF

2018-2021

Completed

PI

16,22,400

3

Tarun K Patel

ICMR-SRF

01.07.2022-30.06.2024

Ongoing

PI

17,11,680

4

Sripathi Nikhitha

DST-INSPIRE

01/01/2023 to 31/12/2027

Ongoing

PI

3071800