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Prof. K V G Chandra Sekhar

Professor
Department of Chemistry

Medicinal and Synthetic Organic Chemistry
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist. Medchal-500 078
Telangana, India

Sponsored Research Projects

On going projects

1. Design and development of cost effective flexible white organic light emitting diodes using synthesized novel electroluminescent (PPE type metal complexes and coordination complexes) materials (Role: Co-PI)

Project duration: Aug 2024 – Aug 2027

Amount sanctioned: ₹ 49 lakhs

Funding Agency: BRNS

 2. A target guided approach for design, synthesis, and screening of host-directed therapies for TB and associated metabolic disorder (PCOS) in women (Role: Co-PI)

Project duration: May 2024 – May 2027

Amount sanctioned: ₹ 184 lakhs

Funding Agency: ICMR

3. A Target Guided Approach for Design, Synthesis, and Screening of Host-directed Therapies for TB associated Metabolic Disorder (PCOS) in Women (Role: Co-PI)

Project duration: Oct 2023 – Sep 2025

Amount sanctioned: ₹ 30 lakhs

Funding Agency: CDRF - BITS Pilani

4. Discovery and Biological Evaluation of Novel Dual Inhibitors of DprE1 and InhA as Potential Anti- Tubercular Agents (Role: PI)

Project duration: Sep. 2023 – Aug. 2026

Amount sanctioned: ₹ 34.52 lakhs

Funding Agency: Department of Science & Technology, - CRG, New Delhi

5. Design, Synthesis and Evaluation of Novel Thiochromene Analogs as Potential Anti-leishmanial agents (Role: Co-PI)

Project duration: Sep. 2023 – Aug. 2026

Amount sanctioned: ₹ 36.56 lakhs

Funding Agency: Department of Science & Technology, - CRG, New Delhi

6. Design, Synthesis and Biological Evaluation of 1,2,3-triazole Hybrids as Novel Quorum Sensing Inhibitors (Role: PI)

Project duration: Apr. 2022 – Mar. 2025

Amount sanctioned: ₹19.2 lakhs

Funding Agency: Council of Scientific and Industrial Research, New Delhi

Completed projects

1. Development of novel anti-leishmanial analogs loaded with novel Nano-formulations (Role: Co-PI)

Project duration: Apr. 2018 – Mar. 2021

Amount sanctioned: ₹ 60 lakhs

Funding Agency: Department of Biotechnology, New Delhi

2. Structure Based Rational Design and Synthesis of Mycobacterium tuberculosis inhibitors (Role: PI)

Project duration: Jan. 2014 – Dec. 2017

Amount sanctioned: ₹ 22 lakhs

Funding Agency: Department of Science & Technology, SERB New Delhi

3. Synthesis and Biological Activity of Various Triazoles as Effective Antifungal Agents (Role: PI)

Project duration: Nov.2012 – Oct.2015

Amount sanctioned: ₹ 21.44 lakhs

Funding Agency: Department of Biotechnology, New Delhi

4. Synthesis and Pharmacological Evaluation of Bishomo(hetero) aryl piperazines as atypical antipsychotic agents (Role: PI)

Project duration: Apr. 2011 – Mar.2014

Amount sanctioned: ₹ 6.44 lakhs

Funding Agency: University Grants Commission, New Delhi

5. Synthesis and Pharmacological Evaluation of Various Indole Analogues for the Treatment of Schizophrenia (Role: PI)

Project duration: Jul. 2010 – Aug. 2013

Amount sanctioned: ₹ 18.28 lakhs

Funding Agency: Department of Science & Technology, Fast Track Scheme, New Delhi

6. 3-Benzisoxazolyl piperidines and Quinoxalinyl Piperazines as Potential Atypical Antipsychotic Agents (Role: Co-PI)

Project duration: Jan. 2005 – Dec. 2007

Amount sanctioned: ₹ 4.94 lakhs

Funding Agency: University Grants Commission, New Delhi


Under Review Projects

1. One health approach for malaria and leishmaniasis: Design, synthesis and phenotypic screening of novel chromene / thiochromene analogs as potential new pharmacological leads (Role: Co-PI)

Date of Submission: 30 Jul 2024

Amount Estimated: ₹ 74 lakhs

Funding Agency: DST Indo – Italy Bilateral grant

2. Unveiling Therapeutic Horizons: Design, Synthesis, and Evaluation of Novel Monocarboxylate Transporter Inhibitors (MCT1 and MCT4) for Cancer Therapy (Role: PI)

Date of Submission: 12 Mar 2024

Amount Estimated: ₹ 81 lakhs

Funding Agency: ICMR - Investigator-Initiated Research Proposals -Small Grant