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Prof. Onkar Prakash Kulkarni   

Professor,
Department of Pharmacy

Autoimmune diseases (Diabetes, Chronic and Acute Renal Inflammation, Pharmacological evaluation of novel chemical entities and novel biological therapies, Psoriasis and Arthritis), SLE, Tissue regeneration (role of immune cells and immune cells derived mediators)
Birla Institute of Technology & Science, Pilani
Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Dist.-Medchal-500 078
Telangana, India

Projects

Ongoing/Approved Projects    
 
As PI
   
 1 Neurobiology: DBT BUILDER-BITS Pilani  (Hyderabad Campus) Interdisciplinary Life Science Programme for Advanced Research and Education 2021-2026
(Rs 29100000)
DBT
 2 HDAC3 and its functional role in the progression of cognitive deficits as a secondary complication to chronic kidney disease
2023-2026 
(Rs 3100000)
ICMR
 3 Therapeutic potential and functional role of RIP-1/RIP-3 mediated necroptosis pathway in the progression of oral squamous cell carcinoma 2023-2026 DST (SERB) (Approved)
       
As co-investigator    
 1 Therapeutic potential of spironolactone loaded light-responsive sustained release gel depot in treating diabetic retinopathy. PI-Dr.Nirmal J 2021-2024 ICMR
 2 Investigation of functional role and therapeutic potential of nesfatin-1 in Chronic Kidney Disease. PI- Prof. Arti Dhar 2021-2024 ICMR
 3 Synthesis of novel coumarin-based lignans targeting pro-inflammatory cytokines for the treatment of chronic kidney diseases. PI- Prof.A. Sajeli Begum 2021-2024 DST (SERB)
 4 Preclinical development of long acting subconjunctival steroid-sparing agent to treat posterior uveitis. PI-Dr.Nirmal J 2022-2025 DHR
 5 Development of epigenetic modulators as therapeutics for cognitive deficit associated with psychosis using novel selective histone deacetylase-3 inhibitors. PI-Prof Balaram Ghosh 2023-2026 ICMR (Approved)
 6
Development of sensors for studying changes in zinc homeostasis in different cellular events. PI-Prof Anupam Bhattacharya
2023-2026
DST (SERB)
(Approved)
 
       
       
Completed Projects     
As PI    
Sr. No Research area Duration      Funding  agency
 1 Role of immune cell mediators in peripheral nerve injury and regeneration
2015-2017
(Rs 1000000)
BITS Pilani  Hyderabad  campus
 2
Regulation of IL-1beta in diabetic wound healing and regeneration
2016-2019
(Rs 2700000)
DST (Young  Scientist)
 3
Functional role of HDAC5 in chronic kidney disease and renal fibrosis
2016-2019
(Rs 4600000) 
DBT (IYBA   2015)
 4 Determination of wound healing (pro-angiogenic) properties of peptide conjugate
2018-2020
(Rs 800000)
INMAS  (DRDO)
 5
Functional role of histone deacetylase 6 (HDAC6) in the progression of oral squamous cell carcinoma: regulation of IL-1β expression, autophagy and epithelial-mesenchymal-transition (EMT)
2019-2022
(Rs 2600000)
ICMR
       
As co-investigator    
Sr. No  Research area Duration Funding  agency
 1 Development of smart capsule to target colorectal cancer. PI- Dr. VVK Venuganti 2017-2020 DST (SERB)
 2 Investigation on pro-inflammatory cytokine inhibitory low molecular weight metabolites of Pseudomonas sp. ABS-36 for the treatment of renal injury. PI- Prof.A. Sajeli Begum 2017-2020 DST (SERB)