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Prof. Kumar Pranav Narayan

Professor
Department of Biological Sciences

Biodiversity of agriculturally important microorganisms, Liposomal Gene delivery system for targeted therapeutics and diagnostics of cancer, Use of Phyto-compound for the formulation of anti-cancer drugs, biofertilizer and biopesticide
Birla Institute of Technology & Science, Pilani Hyderabad Campus
Jawahar Nagar, Kapra Mandal
Medchal-500 078
Telangana, India

Research Project

Ongoing research project details:

Industry Sponsored

  • EON’s DINI (Diet-Infection-Nutrition-Immunity) Axis approach – Proof of Concept: Immunomodulatory Nutritional Intervention for CRC Management (PI)

Government funding

  • DBT Grant: Glucocorticoid receptor (GR)-targeted liposomal nano-platform for drug sensitization, EMT reversal toward effective treatment of aggressive oral cancer (Multi-Institutional Grant: PI), EON (May 2021 - May 2023)
  • DBT Grant: Antibacterial, host-modulating and regenerative nanofibers membrane for guided tissue regeneration (Multi-Institutional Grant: PI) (Nov 2022 - Nov 2025)
  • DST Grant: CRISPR mediated genetic correction of Sickle Cell disease towards clinical trials in a small patient cohort” (Multi-Institutional Grant: as collaborator with CSIR-IICT)

PI of research funding for fellowship

  • ICMR-SRF Project: Folate receptor mediated targeting of Oral Cancer: therapeutics and mechanistic investigation of tumor regression (PI).
  • JRF-Lady Tata Memorial Trust Award:  Investigating the role of GR mediated liposomal delivery system against OSCC and Tumor Microenvironment for targeted therapeutics (PI)

Completed research Project:

  • In house sponsored project: OC3-Centre for Human Diseases Research (CHDR), Test the efficacy of SHR-mediated drug delivery system for oral cancer.
  • DBT Grant: Transgenic Embryonic stem cell models for studying the role of elevated levels of DNMT1 and DNMT3A in neuropsychiatric disorders funded by DBT, India. (Co-PI) 
  • In house sponsored project: Development of personalized DNA markers in breast cancer patients for early diagnosis and prognosis using a non -invasive method. Seed Grant (Co-PI)
  • In house sponsored project: Screening of steroid hormone receptors and their ligands for targeted delivery of cationic liposome in cancer cells, Research Initiation Grant. (PI).

 Collaborators:

  1. Industrial collaborator: Dr. Anubhab Mukherjee, Principal Scientist, Esperer Onco   Nutrition, Mumbai
  2. Dr. Rajkumar Banerjee (CSIR-IICT, Hyderabad)
  3. Dr. Madhusudan Rao Gummanur, (ACDS, Secunderabad).
  4. Dr. Jyotsnendu Giri, (IIT, Hyderabad)
  5. Dr. Venkata Srilakshmi P (NIT, Warangal)

Acknowledgment:

I thank Director, BITS Pilani Hyderabad Campus for providing fund through CHDR. I also thank DBT, DST, ICMR, EON & Lady Tata Memorial Trust for sponsoring research grant/ fellowship. I sincerely thank my collaborators and highly appreciate their support in running our collaborative grants.