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Dr. Deepak Chitkara

Associate Professor, Department of Pharmacy,
BITS Pilani, Pilani Campus

Pharmaceutics
Department of Pharmacy, Birla Institute of Technology & Science, Pilani- 333031, Rajasthan. India.

Publications

 

Translational Nanomedicine Lab

Translational Nanomedicine Lab

 

 
 
Theme Issues
 
1. Drug and Nucleic Acid Delivery and Targeting to the Brain, Journal of Controlled release, Editors: Ram I Mahato and Deepak Chitkara https://www.sciencedirect.com/journal/journal-of-controlled-release/special-issue/10B85SQBSPR 
 
2.  Nanotechnology-based Delivery Strategies for Protein and Peptide Therapeutics, Journal of Pharamcology and Experimental Therapeutics, Editors: Anupama Mittal and Deepak Chitkara - https://www.aspet.org/aspet/news/news/2022/10/12/call-for-papers-on-protein-and-peptide-therapeutics-for-the-journal-of-pharmacology-and-experimental-therapeutics 
 

Books Edited

  • Molecular Medicines for Cancer: Concepts and Applications of Nanotechnology. Edited by Deepak Chitkara, Anupama Mittal, and Ram I. Mahato (Editors), September 2018, CRC Press, Taylor Francis, Florida, USA

 

Molecular Medicines for Cancer

 

S. No.

Authors

Title

Publication

Year

Volume

Pages

1

Lohia, Aayushi; Sahel, Deepak Kumar; Salman, Mohammad; Singh, Vivek; Mariappan, Indumathi; Mittal, Anupama; Chitkara, Deepak; 

Delivery Strategies for CRISPR/Cas Genome editing tool for Retinal Dystrophies: challenges and opportunities

Asian Journal of Pharmaceutical Sciences

2022

 

 

2

Kandregula, Bhaskar; Narisepalli, Saibhargav; Chitkara, Deepak; Mittal, Anupama; 

Exploration of Lipid-Based Nanocarriers as Drug Delivery Systems in Diabetic Foot Ulcer

Molecular Pharmaceutics

2022

 

 

3

Date, Tushar; Kuche, Kaushik; Chaudhari, Dasharath; Ghadi, Rohan; Sahel, Deepak Kumar; Chitkara, Deepak; Jain, Sanyog; 

Hitting Multiple Cellular Targets in Triple-Negative Breast Cancer Using Dual-Action Cisplatin (IV) Prodrugs for Safer Synergistic Chemotherapy

ACS Biomaterials Science & Engineering

2022

 

 

4

Saini, Komal; Arora, Caamin; Saini, Megha; Sharma, Saurabh; Chitkara, Deepak; Kakkar, Vandita; 

Preclinical safety of tetrahydrocurcumin loaded lipidic nanoparticles incorporated into tacrolimus ointment: In vitro and in vivo evaluation

Food and Chemical Toxicology

2022

167

113260

5

Sahel, Deepak Kumar; Salman, Mohd; Azhar, Mohd; Goswami, Sangam Giri; Singh, Vivek; Dalela, Manu; Mohanty, Sujata; Mittal, Anupama; Ramalingam, Sivaprakash; Chitkara, Deepak; 

Cationic lipopolymeric nanoplexes containing the CRISPR/Cas9 ribonucleoprotein for genome surgery

Journal of Materials Chemistry B

2022

 

 

6

Pukale, Sudeep Sudesh; Sahel, Deepak Kumar; Mittal, Anupama; Chitkara, Deepak; 

Coenzyme Q10 loaded lipid-polymer hybrid nanoparticles in gel for the treatment of psoriasis like skin condition

Journal of Drug Delivery Science and Technology

2022

76

103672

7

Alshahrani, Saad M; Thotakura, Nagarani; Sharma, Saurabh; Quadir, Sheikh Shahnawaz; Chaurawal, Nishtha; Sharma, Sumit; Chitkara, Deepak; Raza, Kaisar; 

Influence of Nanocarrier Type on the Drug Delivery Aspects of Docetaxel: Empirical Evidences

Journal of Pharmaceutical Innovation

2022

 

12-Jan

8

Chaurawal, Nishtha; Misra, Charu; Abul Barkat, Harshita; Jatyan, Reena; Chitkara, Deepak; Barkat, Md; Sharma, Teenu; Singh, Bhupinder; Raza, Kaisar; 

Oral sorafenib-loaded microemulsion for breast cancer: evidences from the in-vitro evaluations and pharmacokinetic studies

Scientific reports

2022

12

15-Jan

9

Jatyan, Reena; Singh, Prabhjeet; Sahel, Deepak Kumar; Karthik, YG; Mittal, Anupama; Chitkara, Deepak; 

Polymeric and small molecule-conjugates of temozolomide as improved therapeutic agents for glioblastoma multiforme

Journal of Controlled Release

2022

350

494-513

10

Bajaj, Tania; Kaur, Vishav Prabhjot; Anwekar, Urvashi; Chitkara, Deepak; Singh, Charan; 

Surface Modification of Micronized Drug Particles for Aerosolization

Organ Specific Drug Delivery and Targeting to the Lungs

2022

 

347-370

11

KC, Sarathlal; Kakoty, Violina; Marathe, Sandhya; Chitkara, Deepak; Taliyan, Rajeev; 

Exploring the neuroprotective potential of rosiglitazone embedded nanocarrier system on streptozotocin induced mice model of Alzheimer’s disease

Neurotoxicity Research

2021

39

240-255

12

Bhat, Medha; Pukale, Sudeep; Singh, Saurabh; Mittal, Anupama; Chitkara, Deepak; 

Nano-enabled topical delivery of anti-psoriatic small molecules

Journal of Drug Delivery Science and Technology

2021

 

102328

13

Ansari, Imran; Chaturvedi, Animesh; Chitkara, Deepak; Singh, Saurabh; 

CRISPR/Cas mediated epigenome editing for cancer therapy

Seminars in Cancer Biology

2021

 

 

14

Bhat, Medha; Jatyan, Reena; Mittal, Anupama; Mahato, Ram I; Chitkara, Deepak; 

Opportunities and challenges of fatty acid conjugated therapeutics

Chemistry and Physics of Lipids

2021

236

105053

15

Mazumdar, Samrat; Chitkara, Deepak; Mittal, Anupama; 

Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers

Acta Pharmaceutica Sinica B

2021

11

903-924

16

Italiya, Kishan S; Singh, Arihant K; Chitkara, Deepak; Mittal, Anupama; 

Nanoparticulate tablet dosage form of lisofylline-linoleic acid conjugate for type 1 diabetes: in situ single-pass intestinal perfusion (SPIP) studies and pharmacokinetics in rat

AAPS PharmSciTech

2021

22

12-Jan

17

Salunkhe, Shubham A; Chitkara, Deepak; Mahato, Ram I; Mittal, Anupama; 

Lipid based nanocarriers for effective drug delivery and treatment of diabetes associated liver fibrosis

Advanced Drug Delivery Reviews

2021

173

394-415

18

KC, Sarathlal; Kakoty, Violina; Krishna, Kowthavarapu Venkata; Dubey, Sunil Kumar; Chitkara, Deepak; Taliyan, Rajeev; 

Neuroprotective efficacy of co-encapsulated rosiglitazone and vorinostat nanoparticle on streptozotocin induced mice model of Alzheimer disease

ACS Chemical Neuroscience

2021

12

1528-1541

19

Singh, Aditi; Tijore, Ajay; Margadant, Felix; Simpson, Chloe; Chitkara, Deepak; Low, Boon Chuan; Sheetz, Michael; 

Enhanced tumor cell killing by ultrasound after microtubule depolymerization

Bioengineering & Translational Medicine

2021

 

e10233

20

Ansari, Imran; Singh, Prabhjeet; Mittal, Anupama; Mahato, Ram I; Chitkara, Deepak; 

2, 2-Bis (hydroxymethyl) propionic acid based cyclic carbonate monomers and their (co) polymers as advanced materials for biomedical applications

Biomaterials

2021

275

120953

21

Sharma, Saurabh; Pukale, Sudeep; Sahel, Deepak Kumar; Singh, Prabhjeet; Mittal, Anupama; Chitkara, Deepak; 

Folate targeted hybrid lipo-polymeric nanoplexes containing docetaxel and miRNA-34a for breast cancer treatment

Materials Science and Engineering: C

2021

128

112305

22

Agarwal, Devesh S; Mazumdar, Samrat; Italiya, Kishan S; Chitkara, Deepak; Sakhuja, Rajeev; 

Bile-Acid-Appended Triazolyl Aryl Ketones: Design, Synthesis, In Vitro Anticancer Activity and Pharmacokinetics in Rats

Molecules

2021

26

5741

23

Pukale, Sudeep Sudesh; Mittal, Anupama; Chitkara, Deepak; 

Topical Application of Vitamin D3-Loaded Hybrid Nanosystem to Offset Imiquimod-Induced Psoriasis

AAPS PharmSciTech

2021

22

17-Jan

24

Singh, Arihant Kumar; Italiya, Kishan S; Narisepalli, Saibhargav; Chitkara, Deepak; Mittal, Anupama; 

Role of Chain Length and Degree of Unsaturation of Fatty Acids in the Physicochemical and Pharmacological Behavior of Drug–Fatty Acid Conjugates in Diabetes

Journal of Medicinal Chemistry

2021

64

14217-14229

25

Sarathlal, KC; Kakoty, Violina; Krishna, Kowthavarapu Venkata; Dubey, Sunil Kumar; Chitkara, Deepak; Taliyan, Rajeev; 

Neuroprotective Efficacy of Co-Encapsulated Rosiglitazone and Vorinostat Nanoparticle on Streptozotocin Induced Mice Model of Alzheimer Disease

ACS chemical neuroscience

2021

12

1528-1541

26

Salunkhe, Shubham; Basak, Moumita; Chitkara, Deepak; Mittal, Anupama; 

Surface functionalization of exosomes for target-specific delivery and in vivo imaging & tracking: Strategies and significance

Journal of Controlled Release

2020

326

599-614

27

Pukale, Sudeep Sudesh; Sharma, Saurabh; Dalela, Manu; kumar Singh, Arihant; Mohanty, Sujata; Mittal, Anupama; Chitkara, Deepak; 

Multi-component clobetasol-loaded monolithic lipid-polymer hybrid nanoparticles ameliorate imiquimod-induced psoriasis-like skin inflammation in Swiss albino mice

Acta Biomaterialia

2020

115

393-409

28

Sharma, Saurabh; Pukale, Sudeep Sudesh; Mittal, Anupama; Chitkara, Deepak; 

Docetaxel and its nanoformulations: how delivery strategies could impact the therapeutic outcome?

Therapeutic Delivery

2020

11

755-759

29

Singh, Prabhjeet; Singh, Aditi; Shah, Shruti; Vataliya, Jalpa; Mittal, Anupama; Chitkara, Deepak; 

RNA interference nanotherapeutics for treatment of glioblastoma multiforme

Molecular Pharmaceutics

2020

17

4040-4066

30

Nandi, Tania; Pradyuth, Sai; Singh, Arihant Kumar; Chitkara, Deepak; Mittal, Anupama; 

Therapeutic agents for targeting desmoplasia: current status and emerging trends

Drug Discovery Today

2020

25

2046-2055

31

Sharma, Saurabh; Pukale, Sudeep Sudesh; Sahel, Deepak K; Agarwal, Devesh S; Dalela, Manu; Mohanty, Sujata; Sakhuja, Rajeev; Mittal, Anupama; Chitkara, Deepak; 

Folate-targeted cholesterol-grafted lipo-polymeric nanoparticles for chemotherapeutic agent delivery

AAPS PharmSciTech

2020

21

21-Jan

32

Italiya, Kishan S; Mazumdar, Samrat; Sharma, Saurabh; Chitkara, Deepak; Mahato, Ram I; Mittal, Anupama; 

Self-assembling lisofylline-fatty acid conjugate for effective treatment of diabetes mellitus

Nanomedicine: Nanotechnology, Biology and Medicine

2019

15

175-187

33

Thotakura, Nagarani; Sharma, Saurabh; Khurana, Rajneet Kaur; Babu, Penke Vijaya; Chitkara, Deepak; Kumar, Vipin; Singh, Bhupinder; Raza, Kaisar; 

Aspartic acid tagged carbon nanotubols as a tool to deliver docetaxel to breast cancer cells: Reduced hemotoxicity with improved cytotoxicity

Toxicology in Vitro

2019

59

126-134

34

Kothari, Ishit R; Mazumdar, Samrat; Sharma, Saurabh; Italiya, Kishan; Mittal, Anupama; Chitkara, Deepak; 

Docetaxel and alpha-lipoic acid co-loaded nanoparticles for cancer therapy

Therapeutic Delivery

2019

10

227-240

35

Sahel, Deepak Kumar; Mittal, Anupama; Chitkara, Deepak; 

CRISPR/Cas system for genome editing: progress and prospects as a therapeutic tool

Journal of Pharmacology and Experimental Therapeutics

2019

370

725-735

36

Singh, Anupama; Thotakura, Nagarani; Singh, Bhupinder; Lohan, Shikha; Negi, Poonam; Chitkara, Deepak; Raza, Kaisar; 

Delivery of docetaxel to brain employing piperine-tagged PLGA-aspartic acid polymeric micelles: improved cytotoxic and pharmacokinetic profiles

AAPS PharmSciTech

2019

20

9-Jan

37

Italiya, Kishan S; Basak, Moumita; Mazumdar, Samrat; Sahel, Deepak K; Shrivastava, Richa; Chitkara, Deepak; Mittal, Anupama; 

Scalable self-assembling micellar system for enhanced oral bioavailability and efficacy of lisofylline for treatment of type-I diabetes

Molecular Pharmaceutics

2019

16

4954-4967

38

Date, Tushar; Nimbalkar, Vaishnavi; Kamat, Jyostna; Mittal, Anupama; Mahato, Ram I; Chitkara, Deepak; 

Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics

Journal of controlled release

2018

271

60-73

39

Mazumdar, Samrat; Italiya, Kishan S; Sharma, Saurabh; Chitkara, Deepak; Mittal, Anupama; 

Effective cellular internalization, cell cycle arrest and improved pharmacokinetics of Tamoxifen by cholesterol based lipopolymeric nanoparticles

International Journal of Pharmaceutics

2018

543

96-106

40

Sharma, Saurabh; Mazumdar, Samrat; Italiya, Kishan S; Date, Tushar; Mahato, Ram I; Mittal, Anupama; Chitkara, Deepak; 

Cholesterol and Morpholine grafted cationic Amphiphilic copolymers for miRNA-34a delivery

Molecular Pharmaceutics

2018

15

2391-2402

41

Kothari, Ishit R; Italiya, Kishan S; Sharma, Saurabh; Mittal, Anupama; Chitkara, Deepak; 

A rapid and precise liquid chromatographic method for simultaneous determination of alpha lipoic acid and docetaxel in lipid-based Nanoformulations

Journal of chromatographic science

2018

56

888-894

42

Uppal, Siddharth; Italiya, Kishan S; Chitkara, Deepak; Mittal, Anupama; 

Nanoparticulate-based drug delivery systems for small molecule anti-diabetic drugs: An emerging paradigm for effective therapy

Acta Biomaterialia

2018

81

20-42

43

Mharugde, Vinayak Sadashiv; Pukale, Sudeep; Sharma, Saurabh; Mittal, Anupama; Chitkara, Deepak; 

Advancements in Polymeric Systems for Nucleic Acid Delivery

 

2018

 

 

44

Kumar, Pramod; Kumar, Rajendra; Singh, Bhupinder; Malik, Ruchi; Sharma, Gajanand; Chitkara, Deepak; Katare, OP; Raza, Kaisar; 

Biocompatible phospholipid-based mixed micelles for tamoxifen delivery: promising evidences from in-vitro anticancer activity and dermatokinetic studies

Aaps pharmscitech

2017

18

2037-2044

45

Sharma, Saurabh; Italiya, Kishan; Mittal, Anupama; Chitkara, Deepak; 

New strategies for cancer management: how can temozolomide carrier modifications improve its delivery?

Therapeutic Delivery

2017

8

475-477

46

Italiya, Kishan S; Sharma, Saurabh; Kothari, Ishit; Chitkara, Deepak; Mittal, Anupama; 

Simultaneous estimation of lisofylline and pentoxifylline in rat plasma by high performance liquid chromatography-photodiode array detector and its application to pharmacokinetics in rat

Journal of Chromatography B

2017

1061

49-56

47

Mittal, Anupama; Chitkara, Deepak; 

Structural modifications in polymeric micelles to impart multifunctionality for improved drug delivery

Therapeutic delivery

2016

7

73-87

48

Chitkara, Deepak; Singh, Saurabh; Mittal, Anupama; 

Nanocarrier-based co-delivery of small molecules and siRNA/miRNA for treatment of cancer

Therapeutic Delivery

2016

7

245-255

49

Thakur, Chanchal Kiran; Thotakura, Nagarani; Kumar, Rajendra; Kumar, Pramod; Singh, Bhupinder; Chitkara, Deepak; Raza, Kaisar; 

Chitosan-modified PLGA polymeric nanocarriers with better delivery potential for tamoxifen

International journal of biological macromolecules

2016

93

381-389

50

Chitkara, Deepak; Mittal, Anupama; Mahato, Ram I; 

miRNAs in pancreatic cancer: therapeutic potential, delivery challenges and strategies

Advanced drug delivery reviews

2015

81

34-52

51

Mittal, Anupama; Chitkara, Deepak; Kumar, Neeraj; Pawar, Rajendra; Domb, Avi; Corn, Ben; 

Regional Drug Therapy: Polymeric Carriers for

Encyclopedia of Biomedical Polymers and Polymeric Biomaterials, 11 Volume Set

2015

 

6951-6972

52

Mittal, Anupama; Chitkara, Deepak; Behrman, Stephan W; Mahato, Ram I; 

Efficacy of gemcitabine conjugated and miRNA-205 complexed micelles for treatment of advanced pancreatic cancer

Biomaterials

2014

35

7077-7087

53

Wen, Di; Chitkara, Deepak; Wu, Hao; Danquah, Michael; Patil, Renukadevi; Miller, Duane D; Mahato, Ram I; 

LHRH-conjugated micelles for targeted delivery of antiandrogen to treat advanced prostate cancer

Pharmaceutical research

2014

31

2784-2795

54

Chitkara, Deepak; Mittal, Anupama; Mahato, Ram I; Kumar, Neeraj; 

Core-shell nanoparticulate formulation of gemcitabine: lyophilization, stability studies, and in vivo evaluation

Drug delivery and translational research

2014

4

439-451

55

Singh, Saurabh; Chitkara, Deepak; Kumar, Virender; Behrman, Stephen W; Mahato, Ram I; 

miRNA profiling in pancreatic cancer and restoration of chemosensitivity

Cancer letters

2013

334

211-220

56

Chitkara, Deepak; Kumar, Neeraj; 

BSA-PLGA-based core-shell nanoparticles as carrier system for water-soluble drugs

Pharmaceutical research

2013

30

2396-2409

57

Chitkara, Deepak; Mittal, Anupama; Behrman, Stephan W; Kumar, Neeraj; Mahato, Ram I; 

Self-assembling, amphiphilic polymer–gemcitabine conjugate shows enhanced antitumor efficacy against human pancreatic adenocarcinoma

Bioconjugate chemistry

2013

24

1161-1173

58

Singh, Saurabh; Chitkara, Deepak; Mehrazin, Reza; Behrman, Stephen W; Wake, Robert W; Mahato, Ram I; 

Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway

PloS one

2012

7

e40021

59

Chitkara, Deepak; Singh, Saurabh; Kumar, Virender; Danquah, Michael; Behrman, Stephen W; Kumar, Neeraj; Mahato, Ram I; 

Micellar delivery of cyclopamine and gefitinib for treating pancreatic cancer

Molecular pharmaceutics

2012

9

2350-2357

60

Chitkara, Deepak; Nikalaje, Sanjay K; Mittal, Anupama; Chand, Mahesh; Kumar, Neeraj; 

Development of quercetin nanoformulation and in vivo evaluation using streptozotocin induced diabetic rat model

Drug delivery and translational research

2012

2

112-123

61

Mittal, Anupama; Kurapati, Phaneendra; Chitkara, Deepak; Kumar, Neeraj; 

In vitro release behavior of paclitaxel and carboplatin from poly (L-lactide) microspheres dispersed in thermosensitive biodegradable gel for combination therapy

International Journal of Drug Delivery

2011

3

245

62

Jain, Jay Prakash; Chitkara, Deepak; Kumar, Neeraj; 

Polyanhydrides as localized drug delivery carrier: an update

Expert opinion on drug delivery

2008

5

889-907

63

Mittal, Anupama; Chitkara, Deepak; Kumar, Neeraj; 

HPLC method for the determination of carboplatin and paclitaxel with cremophorEL in an amphiphilic polymer matrix

Journal of chromatography B

2007

855

211-219

64

Mittal, Anupama; Chitkara, Deepak; Kumar, Neeraj; Pawar, Rajendra; Domb, Avi; Corn, Ben; 

Polymeric Carriers for Regional Drug Therapy

Smart Polymers: Applications in Biotechnology and Biomedicine

2007

2

359

65

Chitkara, Deepak; Shikanov, Ariella; Kumar, Neeraj; Domb, Abraham J; 

Biodegradable injectable in situ depot‐forming drug delivery systems

Macromolecular bioscience

2006

6

 

Book Chapters

  1. Vinayak Sadashiv Mharugde,  Sudeep Pukale,  Saurabh Sharma,  Anupama Mittal,  Deepak Chitkara, Chapter 16: Advancement in Polymeric System for Nucleic Acid Delivery. In  Molecular Medicines for Cancer: Concepts and Applications of Nanotechnology, In Molecular Medicines for Cancer: Concepts and Applications of Nanotechnology, Eds. Deepak Chitkara, Anupama Mittal, and Ram I. Mahato, September 2018, CRC Press, Taylor Francis, Florida, USA
  2. Mittal, Anupama; Chitkara, Deepak; Kumar, Neeraj; Pawar, Rajendra; Domb, Avi; Corn, Ben. Polymeric Carriers for Regional Drug Therapy. 2007. Smart Polymers: Applications in Biotechnology and Biomedicine. 359.