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Dr. Pragyanshu Khare

Assistant Professor, Department of Pharmacy, BITS Pilani, Pilani Campus

Cell and Molecular Biology, Pharmacology and Toxicology, TRP Channel, Metabolism, Microsurgery
Department of Pharmacy, Birla Institute of Technology & Science, Pilani- 333031, Rajasthan. India.
Dr. Pragyanshu Khare

Publications

 

Journal Publications

 

  1. 1. Kaur J, Kumar V, Kumar V, Shafi S, Khare P , Mahajan N, Bhadada SK, Kondepudi KK, Bhunia RK, Kuhad A, Bishnoi M. Combination of TRP channel dietary agonists induces energy expending and glucose utilizing phenotype in HFD - fed mice. International Journal of Obesity. 202 2; 46(1):153 - 161 (Impact Factor - 5.5 )
  2. Kumar V , Khare, P , Devi K, Kaur J , Kumar V, Konde pudi KK, Bishnoi M. Short‐chain fatty acids increase intracellular calcium levels and enhance gut hormone release from STC‐1 cells via transient receptor potential Ankyrin1.. Fundamental & Clinical Pharm acology.2021; 35(6): 1004 - 1017. (Impact Factor - 2. 7 )
  3. Das NR, Vaidya B, Khare P , Bishnoi M, Sharma SS. Combination of Peroxisome Proliferator - - - Activator Ameliorates Cognitive Deficits, Oxidative Stress, and Inflammation in Rodent Mo del of Current neurovascular research . 2021; 18 (5): 497 - 507. (Impact Factor - 2.3 )
  4. Mahajan N, Khare P , Kondepudi KK, Bishnoi M. TRPA1: Pharmacology, natural activators and role in obesity prevention. Europea n Journal of Pharmacology. 2021; 912: 174553 (Impact Factor - 5.2 )
  5. Khare P , Mahajan N, Singh DP, Kumar V, Kumar V, Mangal P, Boparai RK, Gesing A, Bhadada SK, Sharma SS, Kondepudi K. Allicin, a dietary trpa1 agonist, prevents high fat diet - induced dysregulation of gut hormones and associated complications. Food & Function. 2021. 12(22), 11526 - 11536 (Impact Factor - 6 .3)
  6. Khare P , Maurya R, Bhatia R, Mangal P, Singh J, Podili K, Bishno i M, Kondepudi KK. Polyphenol rich extracts of finger millet and kodo millet ameliorate high fat diet - induced metabolic alterations. Food & Function. 2020;11(11):9833 - 47. (Impact Factor - 6 .3)
  7. Sharma S*, Khare P* , Kumar A, Chunduri V, Kumar A, Kapoor P, Man gal P, Kondepudi KK, Bishnoi Induced Alterations in Mice: Nutrigenomics Studies. Molecular nutrition & food research. 2020;64(13):1900999. (Impact Factor - 6.5 )
  8. Kumar V, Mahajan N, Khare P , Kondepudi KK, Bishnoi M. Role of TRPV1 in colonic mucin production and gut microbiota profile. European Journal of Pharmacology. 2020;888:173567 .(Impact Factor - 5.2 )
  9. Deol PK, Khare P , Singh DP, Bishnoi M, Kondepudi KK, Kaur IP. Pharmabiotic beads w ith improved encapsulation and gut survival for management of colonic inflammation associated gut derangements. Journal of Drug Targeting. 2020 ;28(10):1053 - 62. (Impact Factor - 5.0 )
  10. Thapak P, Khare P , Bishnoi M, Sharma SS. Neuroprotective Effect of 2 - Aminoeth oxydiphenyl Borate (2 - - Induced Memory Dysfunction: A Mechanistic Study. Cellular and Molecular Neurobiology. 2020 ; 21:1 - 3.( Impact Factor - 4.2 )
  11. Singh S, Bhatia R, Khare P , Sharma S, Rajarammohan S, Bishnoi M, Bhadada SK, Sharma SS, Kaur J, Kondepudi KK. Anti - inflammatory Bifidobacterium strains prevent dextran sodium sulfate induced colitis and associated gut microbial dysbiosis in mice. Scientific reports. 2020;10(1):1 - 4 .(Impact Factor - 4.9 )
  12. Singh R, Bansal Y, Sodhi RK, Khare P , Bishnoi M, Kondepudi KK, Medhi B, Kuhad A. Role of TRPV1/TRPV3 channels in olanzapine - induced metabolic alteration: Possible involvement in hypothalamic energy - sensing, appetite regulation, inflammation and mesolimbic pathway. Toxicology and Applied Pharmacology. 202 0;402:115124. (Impact Factor - 4.4 )
  13. Resham K, Khare P , Bishnoi M, Sharma SS. Neuroprotective effects of isoquercitrin in diabetic neuropathy via Wnt/β‐catenin signaling pathway inhibition. BioFactors. 2020;46(3):411-20.(Impact Factor-6.4)
  14. Khare P , Chauhan A, Kumar V, Kaur J, Mahajan N, Kumar V, Gesing A, Chopra K, Kondepudi KK, Bishnoi M. Bioavailable Menthol (Transient Receptor Potential Melastatin - 8 Agonist) Induces Energy Expending Phenotype in Differen tiating Adipocytes. Cells. 2019 ;8(5). pii: E383 . (Impact Factor - 7 .6)
  15. Deol PK, Khare P, Bishnoi M , Kondepudi KK , Kaur IP . Coadministration of ginger extract - Lactobacillus acidophilus (cobiotic) reduces gut inflammation and oxidative stress via downregulation of COX - 2, i - N OS, and c - Myc. Phytother Res. 2 018;32(10):1950 - 1956. (Impact Factor - 6.4)
  16. Khare P , Mangal P, Baboota RK, Jagtap S, Kumar V, Singh DP, Boparai RK, Sharma SS, Khardori R, Bhadada SK, Kondepudi KK, Chopra K, Bishnoi M. Involvement of Gluc agon in Preventive Effect of Menthol Against High Fat Diet Induced Obesity in Mice. Front Pharmacol. 2018;9:1244. (Impact Factor - 5.9 )
  17. Bishnoi M, Khare P , Brown L, Panchal SK. Transient receptor potential (TRP) channels: a metabolic TR(i)P to obesity prevention and therapy. Obes Rev. 2018 ;19(9):1269 - 1292 . (Impact Factor - 10.8 )
  18. Baboota RK, Khare P Mangal P , Singh DP , Bhutani KK , Kondepudi KK , Kaur J , Bishnoi M . Dihydrocapsiate supplementation prevent ed high - fat diet - induced adiposity, hepatic steatosis, glucose intolerance, and gut morphological alterations in mice. Nutr Res. 2018;51:40 - 56. (Impact Factor - 3.8 )
  19. Khare P , Datusalia AK, Sharma SS. Parthenolide, an NF - Inhibitor Ameliorates Diabetes - Induced Behavioural Deficit, Neurotransmitter Imbalance and Neuroinflammation in Type 2 Diabetes Rat Model. Neuromolecular Med. 2017;19(1):101 - 112. (Impact Factor - 4.1 )
  20. Sarma SM*, Khare P* , Jag tap S, Singh DP, Baboota RK, Podili K, Boparai RK, Kaur J, Bhutani KK, Bishnoi M, Kondepudi KK. Kodo millet whole grain and bran supplementation prevents high - fat diet induced derangements in a lipid profile, inflammatory status and gut bacteria in mi ce. F ood & Function. 2017 ;8(3):1174 - 1183 . (Impact Factor - 6 .3)
  21. Deol PK, Khare P , Singh DP, Soman G, Bishnoi M, Kondepudi KK, Kaur IP. Managing colonic inflammation associated gut derangements by systematically optimised and targeted ging er extract - Lactobacillus acidophilus loaded pharmacobiotic alginate beads. Int J Biol Macromol. 20 17 ;105(Pt 1):81 - 91 . (Impact Factor - 8.0 )
  22. Jagtap S, Khare P , Mangal P, Kondepudi KK, Bishnoi M, Bhutani KK. Effect of mahan imbine, an alkaloid from curry leaves, on high - fat diet - induced adiposity, insulin resistance, and inflammatory alterations. Biofactors. 2017;43(2):220 - 231. (Impact Factor - 6.4 )
  23. Mangal P, Khare P , Jagtap S, Bishnoi M, Kondepudi KK, B hutani KK. Screening of six Ayurvedic medicinal plants for anti - obesity potential: An investigation on bioactive constituents from Oroxylum indicum (L.) Kurz bark. J Ethnopharmacol. 2017;197:138 - 146. (Impact Factor - 5.2 )
  24. Khare P , Jagtap S, Jain Y, Baboota RK, Mangal P, Boparai RK, Bhutani KK, Sharma SS, Premkumar LS, Kondepudi KK, Chopra K, Bishnoi M. Cinnamaldehyde supplementation prevents fasting - induced hyperphagia, lipid accumulation, and inflammation in high - fat diet - fe d mice. Biofactors. 2016 ;42(2):201 - 11. ( Impact Factor - 6.4 )
  25. Jagtap S, Khare P , Mangal P, Kondepudi KK, Bishnoi M and Bhutani KK. Protective effects of phyllanthin, a lignan from Phyllanthus amarus, against progression of high fat diet induced metabolic disturbances in mice. RSC Advances . 2016; 6(63): 58343 - 58353. (Impact Factor - 4.0 )
  26. Sharma S, Chunduri V, Kumar A, Kumar R, Khare P , Kondepudi KK, Bishnoi M, Garg M. Anthocyanin bio - fortified colored wheat: Nutritional and functional charac terization. PLoS One. 2018 ;13(4):e0194367 . (Impact Factor - 3.7 )
  27. Singh DP, Khare P , Bijalwan V, Baboota RK, Singh J, Kondepudi KK, Chopra K, Bishnoi M. Coadministration of isomalto - oligosaccharides augments metabolic health benefits of cinnamaldehyde in high fat die t fed mice. Biofactors. 2017 ;43(6):821 - 835 . (Impact Factor - 6.4 )
  28. Singh DP, Khare P , Zhu J, Kondepudi KK, Singh J, Baboota RK, Boparai RK, Khardori R, Chopra K, Bishnoi M. A novel cobiotic - based preventive approach against high - fat diet - induced adiposity, nonalcoholic fatty liver and gut derangement in mice. Int J Obes (Lond). 2016;40(3):487 - 96 . (Impact Factor - 5.5 )
  29. Singh DP, Singh J, Boparai RK, Zhu J, Mantri S, Khare P , Khardori R, Kondepudi KK, Chopra K, Bishnoi M. Isomalto - oligosaccharides, a prebiotic, functionally augment green tea effects against high fat diet - induced metaboli c alterations via preventing gut dysba cteriosis in mice. Pharmacol . Research 2017 Sep;123:103 - 113 . ( Impact Factor - 10.3 )
  30. Singh DP, Singh S, Bijalwan V, Kumar V, Khare P , Baboota RK, Singh P, Boparai RK, Singh J, Kondepudi KK , Chopra K, Bishnoi M. Co - supplementation of isomalto - oligosaccharides potentiates metabolic health benefits of polyphenol - rich cranberry extract in high fat diet - fed mice via enhanced gut butyrate production. Eur J Nutr. 2018 ;57(8):2897 - 2911. (Impact Factor - 4.8 )
  31. Sarma SM, Singh DP, Singh P, Khare P , Mangal P, Singh S, Bijalwan V, Kaur J, Mantri S, Boparai RK, Mazumder K, Bishnoi M, Bhutani KK, Kondepudi KK. Finger millet arabinoxylan protects mice from high - fat diet induced l ipid derangements, inflammation, endotoxemia and gut bacterial dysbiosis. Int J B iol Macromol. 2018;106:994 - 1003 . (Impact Factor - 8.0 )
  32. Murtaza N, Baboota RK, Jagtap S, Singh DP, Khare P , Sarma SM, Podili K, Alagesan S, Chandra TS, Bhutani KK, Boparai RK, Bishnoi M, Kondepudi KK. Finger millet bran supplementation alleviates obesity - induced oxidative stress, inflammation and gut microbial derangements in high - fat diet - fed mice. Br J Nutr. 2014;112(9):1447 - 58. (Impact Factor - 3.7) 4.1
  33. Singh S, Bhatia R, Singh A, Singh P, Kaur R, Khare P , Purama RK, Boparai RK, Rishi P, Ambalam P, Bhadada SK, Bishnoi M, Kaur J, Kondepudi KK. Probiotic attributes and prevention of LPS - induced pro - inflammatory stress in RAW264.7 macrophages and human intestinal epithelial cell line (Caco - 2) by newly isolated Weissella cibaria strains. Food & Function. 2018;9(2):1254 - 1264 . ( Impact Factor - 6 .3)

Book Chapter

  • Bishnoi, M., Khare, P ., Kondepudi, K. K., & Premkumar, L. S. (2015). The Role of TRPV1 in Acquired Diseases: Therapeutic Potential of TRPV1 Modulators. In TRP Channels as Therapeutic Targets (pp. 35 - 58). Academic Press (Elsevier)