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Integrated First Degree

B.E.(Biotechnology)
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Uma S Dubey

pilani Biological Sciences

Associate Professor, Department of Biological Sciences, BITS Pilani, Pilani Campus

Immunology
Department of Biological Sciences, Birla Institute of Technology & Science, Pilani- 333031, Rajasthan. India.
uma@pilani.bits-pilani.ac.in
Tel No: +91-1596-255633 | Mobile No: +91-7727021964
Fax No:- +91-1596-244183

Research Interest

  • Cancer Biology: I am working on anticancer properties of camel milk proteins and their potential role as a drug delivery molecule. I have filed a patent on purification procedure of isolating lactoferrin from camel milk whey. Also a casein nanoparticle has been developed for better delivery of drugs, specially, Sorafenib, a drug used against hepatocellular carcinoma. Furthermore, I am also studying cell migration, reactive oxygen species induction, DNA fragmentation, the cell cycle, gene expression, and associated cytotoxic mechanisms upon treatment of transformed cells with camel milk lactoferrin or Sorafenib encapsulated in camel milk casein nanoparticles. I am also interested in comparative bioinformatics studies of camel milk proteins across various mammalian species.
  • Mathematical Modelling of Immune system: system: I have been involved in studying the interaction of various components of the immune system with each other, with cancer cells and with infectious agents in the presence and absence of environmental toxicants. The analysis requires theoretic, mathematically and computational input.
  • Cellular Immune Responses: : I have been interested in comparative studying on Lymphocyte proliferation, Natural Killer cell function and Antibody dependent cellular cytotoxicity at normal and febrile temperatures. Also the cell cycle proliferation kinetics of lymphocytes and cell lines is of interest

Research Groups

Full Time Ph.D. Students


Manohar

Manohar

Manohar Lal (2012PHXF0413P): (Thesis completed)
Title: Studies on Anti-cancer Properties of Camel Milk Components

 

neelam



Neelam Mahala: (2015PHXF0419P): (Thesis submitted)
Title: Studies on Anticancer Properties of Camel Milk Lactoferrin

Aastha
Aastha
Aastha Mittal: 2017PHXF0001 (Ongoing)
Title: Development, Characterization, and Evaluation of Anticancer Drug Loaded Polymeric Nanoparticles
Co-Guide: Prof. Rajeev Taliyan (Dept of Pharmacy, BITS Pilani)
Co-Guide: Prof. Sunil Dubey, General Manager, Medical Research, R&D Healthcare Division, Emami Ltd

Chetan Srivastava 


Preeti Dubey: 2011PHXF033P: (Thesis Completed)
Title: Stability Analysis and Simulation of Epidemiological Models
Designation: Co-Guide
Guide: Prof. Balram Dubey

Part Time Ph.D. Students (Thesis Completed)


Kumar Avishek (ID No. 2013PHXF107P)
Title: Studies on Generation and Characterization of Live Attenuated Leishmania
Parasites as Vaccine Candidates of Visceral Leishmaniasis
Designation : Co-Guide
Guide: Dr. Poonam Salotra Designation: Director in-Charge & Scientist G, National Institute of Pathology (ICMR), New Delhi


NITU KUMARI (ID No 2013PHXP109P)
Title: Identification and Characterization of Urinary Proteins as Post Surgery
Surveillance Markers in Urothelial Carcinoma
Name of Guide: s Dr. SUNITA SAXENA, Consultant & Ex-Director, National Institute
of Pathology, I.C.M.R, Safdarjung Hospital Campus, New, Delhi
Name of Co-Guide: Dr. USHA AGRAWAL, Deputy Director, National Institute of Pathology, New Delhi
Name of Co-Guide: Dr. UMA. S. DUBEY, Associate Professor, BITS Pilani

Shreshtha Malvia (ID. No. 2013PHXF111P)
Title: Study of Gene Expression and Methylation Profiles Associated with Early and
Late Onset Indian Breast Cancer Patients
Name of Guide: Dr. Sunita Saxena , Consultant & Ex-Director, National Institute of
Pathology, I.C.M.R, Safdarjung Hospital Campus, New Delhi
Co- Guide: Dr. S. A. Raju Bagadi,Scientist, Scientist D National Institute of Pathology,
I.C.M.R, Safdarjung Hospital Campus, New, Delhi
Co-Guide: Uma S. Dubey, , Associate Professor, Department of Biological Sciences,BITS PIlani

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