results 265-276 of 557
A Posteriori Error Analysisf Parabolic Integro-Differential Equations with Positive Type Kernels
26/12/2022
Inventors: Gujji MohanMurali Reddy
The study focuses on a posteriori error analysis for parabolic integro-differential equations that involve positive type kernels. These equations combine integral and differential terms and are used to model various physical and engineering processes. Key aspects include:
A Posteriori Error Analysis: Developing techniques to estimate and quantify the error in numerical...
The study focuses on a posteriori error analysis for parabolic integro-differential equations that involve positive type kernels. These equations combine integral and differential terms and are used to model various physical and engineering processes. Key aspects include:
A Posteriori Error Analysis: Developing techniques to estimate and quantify the error in numerical solutions after computations are completed, helping to assess solution accuracy.
Parabolic Integro-Differential Equations: Examining equations that involve both parabolic partial differential equations and integral terms with positive type kernels, which influence the problem's behavior and solution.
Positive Type Kernels: Analyzing how these specific kernels affect the error estimates and solution strategies.
The goal is to improve the reliability and accuracy of numerical methods for solving complex parabolic integro-differential equations by providing robust error estimation techniques. (Mathematics)
Study of Ergodic Theorems for Γ-actions on a Group X, where Γ is a Subgroup of Aut(X)
26/12/2022
Inventors: Sharan Gopal
The study focuses on ergodic theorems applied to Γ-actions on a group X, where Γ is a subgroup of the automorphism group Aut(X). Ergodic theorems deal with the statistical properties of dynamical systems, providing insights into long-term behavior. Key aspects of the study include:
Γ-Actions: Investigating how a subgroup Γ of...
The study focuses on ergodic theorems applied to Γ-actions on a group X, where Γ is a subgroup of the automorphism group Aut(X). Ergodic theorems deal with the statistical properties of dynamical systems, providing insights into long-term behavior. Key aspects of the study include:
Γ-Actions: Investigating how a subgroup Γ of Aut(X) acts on the group X and the resulting dynamical behavior.
Ergodic Theorems: Applying classical and advanced ergodic theorems to understand the statistical properties and invariants of these actions.
Mathematical Implications: Analyzing how these theorems contribute to understanding the structure and properties of X under Γ-actions, including potential applications in dynamical systems and group theory.
The goal is to deepen the understanding of ergodic behavior in the context of group actions and their implications for various mathematical structures. (Mathematics)
Completely Positive Maps and Quantum Conditional Entropy
26/12/2022
Inventors: Nirman Ganguly
The study investigates the relationship between completely positive maps and quantum conditional entropy within the framework of quantum information theory. Key aspects include:
Completely Positive Maps: These are mathematical operations on quantum states that preserve positivity, essential for quantum state transformations and measurements.
Quantum Conditional Entropy: A measure of the amount of...
The study investigates the relationship between completely positive maps and quantum conditional entropy within the framework of quantum information theory. Key aspects include:
Completely Positive Maps: These are mathematical operations on quantum states that preserve positivity, essential for quantum state transformations and measurements.
Quantum Conditional Entropy: A measure of the amount of uncertainty or information contained in a quantum system given the state of another system.
The research explores how completely positive maps influence or relate to the properties and behavior of quantum conditional entropy, with implications for understanding quantum correlations, information processing, and entropy in quantum systems. The goal is to provide deeper insights into the mathematical and physical connections between these fundamental concepts in quantum information theory. (Mathematics)
Biosensor Monitoring of Signaling Dynamics in the Intracellular Pathogen Toxoplasma gondii
23/09/2022
Inventors: Nishith Gupta, Takeharu Nagai
The study focuses on using biosensors to monitor signaling dynamics within the intracellular pathogen Toxoplasma gondii. T. gondii is a protozoan parasite that can cause significant infections in humans. Key aspects include:
Biosensor Development: Designing and utilizing advanced biosensors to track real-time signaling pathways and molecular interactions within T. gondii.
Signaling Dynamics:...
The study focuses on using biosensors to monitor signaling dynamics within the intracellular pathogen Toxoplasma gondii. T. gondii is a protozoan parasite that can cause significant infections in humans. Key aspects include:
Biosensor Development: Designing and utilizing advanced biosensors to track real-time signaling pathways and molecular interactions within T. gondii.
Signaling Dynamics: Investigating how the parasite’s intracellular signaling mechanisms influence its survival, replication, and interaction with host cells.
Pathogen Insights: Understanding how signaling pathways contribute to the pathogen's pathogenicity and persistence.
The goal is to enhance our knowledge of T. gondii biology and identify potential targets for therapeutic interventions by monitoring its internal signaling processes. (Biological Science)
Understanding the role of PERK and MAM Signaling during HD condition
13/03/2023
Inventors: Shuvadeep Maity, Deabashree B, Pragya Komal and Kirtimaan Syal
The study explores the role of PERK (PKR-like ER kinase) and mitochondrial-associated membrane (MAM) signaling in Huntington's Disease (HD). PERK is a component of the unfolded protein response (UPR) that helps manage cellular stress, while MAMs are sites of communication between the endoplasmic reticulum (ER) and mitochondria. The research focuses...
The study explores the role of PERK (PKR-like ER kinase) and mitochondrial-associated membrane (MAM) signaling in Huntington's Disease (HD). PERK is a component of the unfolded protein response (UPR) that helps manage cellular stress, while MAMs are sites of communication between the endoplasmic reticulum (ER) and mitochondria. The research focuses on:
PERK Function: Investigating how PERK influences cellular stress responses and protein homeostasis in HD.
MAM Signaling: Analyzing how disruptions in MAM signaling affect mitochondrial function and contribute to HD pathology.
Disease Mechanisms: Understanding how altered PERK and MAM interactions impact neurodegeneration in HD.
The aim is to clarify the mechanisms linking PERK and MAM signaling to HD progression and identify potential therapeutic targets. (Biological Science)
Understanding the Novel Role of PERK in the context of ER-Mitochondrial Communication in NAFLD
04/01/2023
Inventors: Shuvadeep Maity, Pragya Komal and Kirtiman Syal
The study investigates the novel role of PERK (PKR-like ER kinase) in endoplasmic reticulum (ER) and mitochondrial communication in non-alcoholic fatty liver disease (NAFLD). PERK is a key component of the unfolded protein response (UPR) that helps manage cellular stress. The research explores how PERK influences the interaction between the...
The study investigates the novel role of PERK (PKR-like ER kinase) in endoplasmic reticulum (ER) and mitochondrial communication in non-alcoholic fatty liver disease (NAFLD). PERK is a key component of the unfolded protein response (UPR) that helps manage cellular stress. The research explores how PERK influences the interaction between the ER and mitochondria, which is crucial for cellular metabolism and stress responses. Key aspects include:
Mechanistic Insights: Understanding how PERK affects ER-mitochondrial signaling and function in NAFLD.
Disease Implications: Examining the impact of disrupted ER-mitochondrial communication on NAFLD progression.
Potential Targets: Identifying new therapeutic targets for improving NAFLD management by modulating PERK activity.
The goal is to provide deeper insights into NAFLD pathogenesis and develop targeted therapies to manage this condition more effectively. (Biological Science)
Exploiting Adaptive Data-Rate Technique for Longer Network Lifetime & Resource Allocation of LoRa based IoT Applications
20/03/2023
Inventors: Nikumani Choudhury
The study explores using Adaptive Data-Rate (ADR) techniques to extend network lifetime and optimize resource allocation in LoRa-based IoT applications. LoRa (Long Range) is a low-power, wide-area network technology for IoT devices. ADR dynamically adjusts the data transmission rate and power settings based on network conditions and device requirements. Key...
The study explores using Adaptive Data-Rate (ADR) techniques to extend network lifetime and optimize resource allocation in LoRa-based IoT applications. LoRa (Long Range) is a low-power, wide-area network technology for IoT devices. ADR dynamically adjusts the data transmission rate and power settings based on network conditions and device requirements. Key aspects of the study include:
Network Lifetime: Evaluating how ADR can reduce energy consumption and extend the operational life of IoT devices by adjusting data rates and transmission power.
Resource Allocation: Optimizing the use of network resources to improve efficiency and performance.
Implementation: Analyzing ADR's impact on network scalability and reliability in various IoT scenarios.
The aim is to enhance the effectiveness of LoRa networks, making them more efficient and sustainable for diverse IoT applications.
(CS&IS)
Study of Late-Time Cosmic Acceleration in Curvature-Less and Torsion-Less Theories of Gravity with Recent Observations
14/03/2023
Inventors: Pradyumn Kumar Sahoo
The study explores late-time cosmic acceleration in theories of gravity that do not incorporate curvature or torsion, using recent observational data. Traditional gravity models often include curvature and torsion components to explain cosmic phenomena. This research examines alternative theories where these elements are absent, focusing on how such models account...
The study explores late-time cosmic acceleration in theories of gravity that do not incorporate curvature or torsion, using recent observational data. Traditional gravity models often include curvature and torsion components to explain cosmic phenomena. This research examines alternative theories where these elements are absent, focusing on how such models account for the observed acceleration of the universe's expansion. By analyzing data from sources like supernovae, the cosmic microwave background, and large-scale structure surveys, the study aims to evaluate the effectiveness of these curvature-less and torsion-less theories in explaining cosmic acceleration and their potential to challenge conventional cosmological models. (Mathematics)
Design and Development of a Miniature Broad Band Vibration Energy Harvester to Power Biomedical Implantable Device
23/12/2022
Inventors: Brajesh Kumar Panigrahi, Sabareesh G R
The study involves designing and developing a miniature broadband vibration energy harvester intended for powering biomedical implantable devices. This harvester converts mechanical vibrations from bodily movements into electrical energy, addressing the challenge of powering implants sustainably. Key elements include:
Miniaturization: Creating a compact device that fits within the constraints of implantable...
The study involves designing and developing a miniature broadband vibration energy harvester intended for powering biomedical implantable devices. This harvester converts mechanical vibrations from bodily movements into electrical energy, addressing the challenge of powering implants sustainably. Key elements include:
Miniaturization: Creating a compact device that fits within the constraints of implantable technology.
Broadband Performance: Ensuring the harvester can efficiently capture and convert a wide range of vibration frequencies.
Integration: Incorporating the harvester into biomedical devices to reduce reliance on external batteries and enhance the longevity and functionality of implants.
The goal is to provide a reliable, self-sustaining power source for medical implants. (Mechanical Engineering)
Tailor-made, Tumor-Targeted Vitaprotein Nanoparticles of Lapatinib and Letrozole as NanoChemo-Cocktail for Hormone-Receptor-Amplified Advanced Metastatic Breast Cancers Treatment
09/01/2023
Inventors: Swati Biswas, Balaram Ghosh
The study develops tailor-made, tumor-targeted vitaprotein nanoparticles designed to deliver a combination of lapatinib and letrozole for treating hormone-receptor-amplified advanced metastatic breast cancers. Vitaprotein nanoparticles are engineered to target tumor cells specifically, enhancing the delivery of therapeutic agents directly to cancer sites. Lapatinib, a tyrosine kinase inhibitor, and letrozole, an...
The study develops tailor-made, tumor-targeted vitaprotein nanoparticles designed to deliver a combination of lapatinib and letrozole for treating hormone-receptor-amplified advanced metastatic breast cancers. Vitaprotein nanoparticles are engineered to target tumor cells specifically, enhancing the delivery of therapeutic agents directly to cancer sites. Lapatinib, a tyrosine kinase inhibitor, and letrozole, an aromatase inhibitor, are used together to tackle both hormone receptor-positive and HER2-positive breast cancer cells. The goal is to create a nano-chemo-cocktail that improves drug efficacy, minimizes side effects, and offers a more effective treatment strategy for advanced metastatic breast cancer. (Pharmacy)
Synthesis of Transition Metal-Phosphate-Based Nanocomposites and Investigation of their Applications towards Thermal Energy Storage, Thermal Management and Solar Thermal Energy Storage
01/11/2022
Inventors: Sandip S Deshmukh, Rudrarapu Aravind
The study focuses on synthesizing transition metal-phosphate-based nanocomposites and evaluating their applications in thermal energy storage, thermal management, and solar thermal energy storage. Transition metal-phosphate nanocomposites are engineered materials with potentially high thermal stability and energy storage capacity. The research involves:
Synthesis: Developing methods to create these nanocomposites with controlled properties.
Characterization:...
The study focuses on synthesizing transition metal-phosphate-based nanocomposites and evaluating their applications in thermal energy storage, thermal management, and solar thermal energy storage. Transition metal-phosphate nanocomposites are engineered materials with potentially high thermal stability and energy storage capacity. The research involves:
Synthesis: Developing methods to create these nanocomposites with controlled properties.
Characterization: Analyzing their structural, thermal, and performance characteristics.
Applications: Investigating how these materials can be utilized in thermal energy storage systems, thermal management solutions, and solar thermal energy storage, aiming to improve efficiency and effectiveness in managing and storing thermal energy.
The goal is to advance the development of high-performance materials for energy storage and management technologies. (Mechanical Engineering)
Systematic Evaluation of the Role of IRE1 in the Modulation of Chronological Aging via ER -Mitochondrial Crosstalk during Chronic ER Stress
14/10/2022
Inventors: Shuvadeep Maity
The study systematically evaluates the role of IRE1 in regulating chronological aging through its influence on ER-mitochondrial crosstalk during chronic endoplasmic reticulum (ER) stress. IRE1 is a key component of the unfolded protein response (UPR) pathway, which manages cellular stress. The research investigates how IRE1 affects interactions between the ER...
The study systematically evaluates the role of IRE1 in regulating chronological aging through its influence on ER-mitochondrial crosstalk during chronic endoplasmic reticulum (ER) stress. IRE1 is a key component of the unfolded protein response (UPR) pathway, which manages cellular stress. The research investigates how IRE1 affects interactions between the ER and mitochondria, crucial for maintaining cellular homeostasis and aging. By examining these mechanisms under chronic ER stress conditions, the study aims to uncover how IRE1-mediated signaling influences aging processes and cellular longevity, potentially identifying new targets for interventions in age-related diseases and stress-related cellular dysfunctions. (Biological Science)