results 289-300 of 557
An Indigenous Air-Conditioning Facility for Hospitals during the COVID-19 Pandemic
01/06/2022
Inventors: Santanu Prasad Datta
The study focuses on developing an indigenous air-conditioning facility specifically designed for hospitals during the COVID-19 pandemic. The facility aims to address the unique needs of healthcare settings by improving air quality and ensuring effective ventilation to reduce the risk of airborne transmission of the virus. The research involves creating...
The study focuses on developing an indigenous air-conditioning facility specifically designed for hospitals during the COVID-19 pandemic. The facility aims to address the unique needs of healthcare settings by improving air quality and ensuring effective ventilation to reduce the risk of airborne transmission of the virus. The research involves creating a cost-effective and locally sourced air-conditioning system that enhances airflow, filters airborne contaminants, and maintains optimal temperatures in hospital environments. By tailoring the design to pandemic conditions, the facility seeks to improve patient and staff safety, contributing to better infection control and hospital management during health crises. (Mechanical Engineering)
High Precision, Miniaturized and Smart Colorimetric Device for Pesticide Quantification and Monitoring Applications in Food and Environment
24/11/2022
Inventors: Satish Kumar Dubey, Sanket Goel, Arshad Javed
The study focuses on developing a high-precision, miniaturized, and smart colorimetric device for the quantification and monitoring of pesticides in food and environmental samples. This device employs colorimetric techniques to detect and measure pesticide levels with high accuracy, offering a compact and user-friendly solution for on-site analysis. The research aims...
The study focuses on developing a high-precision, miniaturized, and smart colorimetric device for the quantification and monitoring of pesticides in food and environmental samples. This device employs colorimetric techniques to detect and measure pesticide levels with high accuracy, offering a compact and user-friendly solution for on-site analysis. The research aims to enhance the device's sensitivity and specificity, enabling reliable monitoring of pesticide contamination. By integrating advanced materials and smart technology, the device seeks to improve safety and regulatory compliance in food and environmental sectors, providing timely and actionable data to prevent and address contamination issues. (Mechanical Engineering)
Enhancement of Mechanical Properties and Forming Behavior of AZ31 Alloy using Shear Deformation Techniques for Automotive & Aerospace Applications
17/12/2020
Inventors: Swadesh Kumar Singh, Nitin R Kotkunde
The study explores enhancing the mechanical properties and forming behavior of AZ31 magnesium alloy using shear deformation techniques. AZ31 is a magnesium alloy used in automotive and aerospace applications due to its lightweight and high strength. The research investigates how applying shear deformation techniques, such as severe plastic deformation, can...
The study explores enhancing the mechanical properties and forming behavior of AZ31 magnesium alloy using shear deformation techniques. AZ31 is a magnesium alloy used in automotive and aerospace applications due to its lightweight and high strength. The research investigates how applying shear deformation techniques, such as severe plastic deformation, can improve the alloy's mechanical properties, including strength, ductility, and fatigue resistance. Additionally, the study examines how these techniques affect the alloy's ability to be shaped and formed, aiming to optimize its performance and suitability for demanding automotive and aerospace applications. (Mechanical Engineering)
Development of a Cost Effective Solar Energy based Drinking Water cum Cold Storage Facility for Coastal Communities in India
20/01/2022
Inventors: Sandip S Deshmuk, Santanu Prasad Datta
The study focuses on developing a cost-effective solar energy-based facility that provides both drinking water and cold storage for coastal communities in India. This facility aims to address two critical needs: access to clean drinking water and reliable cold storage for perishable goods. By harnessing solar energy, the project seeks...
The study focuses on developing a cost-effective solar energy-based facility that provides both drinking water and cold storage for coastal communities in India. This facility aims to address two critical needs: access to clean drinking water and reliable cold storage for perishable goods. By harnessing solar energy, the project seeks to offer a sustainable and affordable solution for these communities, reducing reliance on costly and environmentally harmful alternatives. The research involves designing and implementing solar-powered systems for water purification and refrigeration, with the goal of improving resource availability and quality of life in coastal areas. (Mechanical Engineering)
Impact of Age/Age-Related Hearing Loss on Basal Forebrain-Modulated Cortical Neurophysiology – A Search for Therapeutic Targets
26/09/2022
Inventors: Srinivasa Prasad Kommajosyula
The study investigates how age and age-related hearing loss affect basal forebrain-modulated cortical neurophysiology, aiming to identify potential therapeutic targets. Age-related hearing loss can alter auditory processing and neurophysiological functions in the brain. This research examines changes in cortical activity and connectivity modulated by the basal forebrain, a critical region...
The study investigates how age and age-related hearing loss affect basal forebrain-modulated cortical neurophysiology, aiming to identify potential therapeutic targets. Age-related hearing loss can alter auditory processing and neurophysiological functions in the brain. This research examines changes in cortical activity and connectivity modulated by the basal forebrain, a critical region involved in attention and cognitive functions. By understanding these impacts, the study seeks to uncover mechanisms underlying auditory and cognitive decline, and to identify potential targets for interventions or treatments to mitigate the effects of hearing loss and age-related cognitive decline. (Pharmacy)
Pre-Clinical Efficacy Evaluation (In Vivo) of Synthetic Peptides & its Formulations – for the Disease Targets Involved in Inflammatory Pathways
05/11/2022
Inventors: D Sriram
The study focuses on the pre-clinical in vivo evaluation of synthetic peptides and their formulations for targeting diseases involved in inflammatory pathways. This research involves testing the efficacy of these synthetic peptides in animal models to assess their ability to modulate or inhibit specific inflammatory processes. The goal is to...
The study focuses on the pre-clinical in vivo evaluation of synthetic peptides and their formulations for targeting diseases involved in inflammatory pathways. This research involves testing the efficacy of these synthetic peptides in animal models to assess their ability to modulate or inhibit specific inflammatory processes. The goal is to determine the peptides' effectiveness in reducing inflammation and alleviating symptoms associated with inflammatory diseases. By evaluating various formulations, the study aims to identify the most promising candidates for further development into therapeutic agents, potentially offering new treatment options for conditions driven by inflammation. (Pharmacy)
A Pilot Study for Evaluation of 15 Copy Number Variants (CNVs) among Schizophrenia Patients from India
12/02/2021
Inventors: K N Mohan
The pilot study evaluates 15 copy number variants (CNVs) in schizophrenia patients from India. CNVs are genomic alterations involving deletions or duplications of DNA segments that can impact gene function and contribute to psychiatric disorders. The research involves analyzing these CNVs in a cohort of Indian schizophrenia patients to identify...
The pilot study evaluates 15 copy number variants (CNVs) in schizophrenia patients from India. CNVs are genomic alterations involving deletions or duplications of DNA segments that can impact gene function and contribute to psychiatric disorders. The research involves analyzing these CNVs in a cohort of Indian schizophrenia patients to identify associations with the disease. By comparing CNV profiles with clinical data, the study aims to uncover potential genetic markers and insights specific to the Indian population, potentially leading to improved diagnostic tools and personalized treatment strategies for schizophrenia. (Biological Science)
Stem Cell Models to Study the Interplay between DNMTs And HDACs in Schizophrenia
31/12/2020
Inventors: K N Mohan
The study focuses on using stem cell models to investigate the interactions between DNA methyltransferases (DNMTs) and histone deacetylases (HDACs) in the context of schizophrenia. DNMTs and HDACs are epigenetic regulators that influence gene expression through modifications of DNA and histones. By employing stem cell-derived neurons or brain-like tissues, the...
The study focuses on using stem cell models to investigate the interactions between DNA methyltransferases (DNMTs) and histone deacetylases (HDACs) in the context of schizophrenia. DNMTs and HDACs are epigenetic regulators that influence gene expression through modifications of DNA and histones. By employing stem cell-derived neurons or brain-like tissues, the research aims to elucidate how these epigenetic factors contribute to the development and progression of schizophrenia. The goal is to better understand the molecular mechanisms underlying the disorder and identify potential therapeutic targets for more effective treatments. (Biological Science)
Computation of Free Energy Changes based on the Confirmations of Biomolecules in Two States During Ligand Binding and Other Biochemical Reactions : A Novel Approach to Screen Drug Targets
04/03/2022
Inventors: Debashree Bandopadhyay
The study introduces a novel computational approach for calculating free energy changes associated with biomolecule conformations in two states during ligand binding and other biochemical reactions. This method aims to enhance drug target screening by accurately predicting how molecular conformational changes affect binding affinities and reaction dynamics. By analyzing the...
The study introduces a novel computational approach for calculating free energy changes associated with biomolecule conformations in two states during ligand binding and other biochemical reactions. This method aims to enhance drug target screening by accurately predicting how molecular conformational changes affect binding affinities and reaction dynamics. By analyzing the free energy landscape of biomolecules in different states, the research seeks to identify potential drug targets more effectively and understand the underlying mechanisms of ligand interactions. This approach could improve drug discovery processes by providing deeper insights into molecular behavior and optimizing therapeutic targets. (Biological Science)
EON’s DINI (Diet-Infection-Nutrition-Immunity) Axis approach – Proof of Concept: Immunomodulatory Nutritional Intervention for CRC Management
19/04/2021
Inventors: Kumar Pranav Narayan
The study investigates EON’s DINI (Diet-Infection-Nutrition-Immunity) Axis approach as a proof of concept for managing colorectal cancer (CRC). This approach integrates dietary strategies, infection control, nutritional support, and immune system modulation to enhance CRC management. The research explores how specific nutritional interventions can influence immune responses and microbial environments to...
The study investigates EON’s DINI (Diet-Infection-Nutrition-Immunity) Axis approach as a proof of concept for managing colorectal cancer (CRC). This approach integrates dietary strategies, infection control, nutritional support, and immune system modulation to enhance CRC management. The research explores how specific nutritional interventions can influence immune responses and microbial environments to improve patient outcomes. By examining the effectiveness of this holistic approach, the study aims to demonstrate the potential of immunomodulatory nutritional strategies in supporting CRC treatment and management, potentially offering a complementary method to traditional therapies. (Biological Science)
Second Messenger (p)ppGpp Mediated Bacterial Persistence and Regulation of SpoT”
30/03/2021
Inventors: Kirtimaan Syal
The study explores the role of the second messenger (p)ppGpp in bacterial persistence and its regulation of the SpoT protein. (p)ppGpp is a key signaling molecule involved in bacterial stress responses and survival strategies, particularly under adverse conditions. The research investigates how (p)ppGpp contributes to bacterial persistence by modulating metabolic...
The study explores the role of the second messenger (p)ppGpp in bacterial persistence and its regulation of the SpoT protein. (p)ppGpp is a key signaling molecule involved in bacterial stress responses and survival strategies, particularly under adverse conditions. The research investigates how (p)ppGpp contributes to bacterial persistence by modulating metabolic processes and stress responses. Additionally, the study examines how SpoT, an enzyme that synthesizes and degrades (p)ppGpp, regulates its levels and influences bacterial adaptation. Understanding these mechanisms could provide insights into bacterial resistance and persistence, offering potential targets for novel antimicrobial strategies. (Biological Science)
Design and Simulation of Improved Polysaccharide based Membranes, the Future Must for Food Packaging
07/07/2022
Inventors: Durba Roy
The study focuses on designing and simulating enhanced polysaccharide-based membranes for food packaging applications. These membranes leverage natural polysaccharides to create sustainable, biodegradable, and functional packaging materials. The research involves optimizing membrane properties such as strength, permeability, and resistance to moisture and gases through computational simulations. The aim is to...
The study focuses on designing and simulating enhanced polysaccharide-based membranes for food packaging applications. These membranes leverage natural polysaccharides to create sustainable, biodegradable, and functional packaging materials. The research involves optimizing membrane properties such as strength, permeability, and resistance to moisture and gases through computational simulations. The aim is to improve the performance of these membranes in preserving food quality and extending shelf life, while also addressing environmental concerns associated with traditional packaging materials. By advancing polysaccharide-based membranes, the study seeks to contribute to more sustainable and effective food packaging solutions for the future. (Chemistry)