results 25-36 of 557
Copper Cathode Quality Improvement And Reduction In Bleed To ETP
15/01/2024
Inventors: Dr. Pradeep Kumar Sow, Dr. Jay Pandey
Improving copper cathode quality and minimizing bleed to electrolytic tough pitch (ETP) involves refining processes that enhance purity through advanced electrolysis techniques and precise control of electrolyte conditions. Optimization of electrolyte composition, temperature, and current densities is crucial for minimizing impurities and ensuring high-quality cathode production. Implementing rigorous quality control...
Improving copper cathode quality and minimizing bleed to electrolytic tough pitch (ETP) involves refining processes that enhance purity through advanced electrolysis techniques and precise control of electrolyte conditions. Optimization of electrolyte composition, temperature, and current densities is crucial for minimizing impurities and ensuring high-quality cathode production. Implementing rigorous quality control measures and real-time monitoring systems further enhances consistency and adherence to stringent industry standards. These efforts aim to reduce material losses and improve the overall efficiency of copper refining processes, supporting sustainable production practices in the metallurgical industry. (Chemical Engineering)
In Vitro And In Vivo Evaluation Of The Functionally-Characterized Broad Spectrum Antifungal Cyclic Lipopetides Homologous Of The Bacillomycin D Family And Their Synthetic Analogs Against Medically Important Mucorales
12/02/2024
Inventors: Dr. Utpal Roy, Dr. Subhasish Roy
In vitro and in vivo evaluation of functionally-characterized broad-spectrum antifungal cyclic lipopeptides, homologous to the bacillomycin D family and their synthetic analogs, assess their efficacy against medically significant Mucorales fungi. These studies aim to validate their antifungal activity through laboratory testing and animal models. By analyzing their potency, spectrum of...
In vitro and in vivo evaluation of functionally-characterized broad-spectrum antifungal cyclic lipopeptides, homologous to the bacillomycin D family and their synthetic analogs, assess their efficacy against medically significant Mucorales fungi. These studies aim to validate their antifungal activity through laboratory testing and animal models. By analyzing their potency, spectrum of action, and mechanisms of action, researchers aim to identify potential candidates for treating fungal infections resistant to current therapies. This research contributes to developing novel antifungal agents to combat infections caused by Mucorales, addressing critical gaps in treatment options for immunocompromised patients. (Biological Science)
Screening The Role Of Shellfish As Conduit In The Transmission Of Antimicrobial Resistance From The Environment Into Human
12/02/2024
Inventors: Dr. Sumit Biswas, Dr. Utpal Roy
Screening the role of shellfish as conduits in the transmission of antimicrobial resistance (AMR) from the environment to humans involves assessing bacterial pathogens and resistance genes present in shellfish. Shellfish, due to their filter-feeding nature, can accumulate bacteria and resistance genes from contaminated waters. Research focuses on identifying and quantifying...
Screening the role of shellfish as conduits in the transmission of antimicrobial resistance (AMR) from the environment to humans involves assessing bacterial pathogens and resistance genes present in shellfish. Shellfish, due to their filter-feeding nature, can accumulate bacteria and resistance genes from contaminated waters. Research focuses on identifying and quantifying AMR bacteria in shellfish and evaluating potential transmission routes to humans through consumption. Understanding this transmission pathway is crucial for assessing public health risks associated with seafood consumption and informing strategies to mitigate AMR spread in aquatic environments and food chains. (Biological Science)
Development Of Biocompatible Nanotechnology Based Non-Viral Delivery Vehicle For Micro Dystrophin Gene Delivery As Therapeutics For Duchenne Muscular Dystrophy
22/02/2024
Inventors: Dr. Meenal Kowshik, Dr. Indrani Talukdar
The development of biocompatible nanotechnology-based non-viral delivery vehicles for micro-dystrophin gene delivery aims to treat Duchenne muscular dystrophy (DMD). These vehicles utilize nanoparticles engineered with biocompatible materials to safely transport micro-dystrophin genes into muscle cells. By evading immune responses and enhancing cellular uptake, they facilitate gene expression, promoting muscle fiber...
The development of biocompatible nanotechnology-based non-viral delivery vehicles for micro-dystrophin gene delivery aims to treat Duchenne muscular dystrophy (DMD). These vehicles utilize nanoparticles engineered with biocompatible materials to safely transport micro-dystrophin genes into muscle cells. By evading immune responses and enhancing cellular uptake, they facilitate gene expression, promoting muscle fiber stabilization and function restoration in DMD patients. This innovative approach targets the genetic cause of DMD, offering potential long-term therapeutic benefits without the drawbacks associated with viral vectors. Ongoing research focuses on optimizing delivery efficiency and ensuring safety for clinical application, advancing personalized treatment strategies for DMD. (Biological Science)
An End-to-End Data storage framwork for heterogeneous Compute Devices (DaSH)
24/01/2024
Inventors: Dr. Arnab Kumar Paul
An End-to-End Data Storage Framework for Heterogeneous Compute Devices (DaSH) facilitates seamless data management across diverse computing platforms. DaSH integrates data storage protocols and optimization strategies tailored to heterogeneous environments, ensuring compatibility and efficiency. It supports distributed computing architectures, leveraging cloud storage and edge computing resources for scalability and performance....
An End-to-End Data Storage Framework for Heterogeneous Compute Devices (DaSH) facilitates seamless data management across diverse computing platforms. DaSH integrates data storage protocols and optimization strategies tailored to heterogeneous environments, ensuring compatibility and efficiency. It supports distributed computing architectures, leveraging cloud storage and edge computing resources for scalability and performance. DaSH enhances data accessibility, security, and synchronization capabilities across devices, enabling real-time data processing and analytics. This framework addresses the complexities of modern computing infrastructures, empowering organizations to leverage heterogeneous compute devices effectively for enhanced productivity and operational flexibility. (CS&IS)
Pathophysiological Investigations Of Sickle Cell Disease And Interventions To Improve Associated Hemorheological Abnormalities
23/01/2024
Inventors: Dr. Suman Kundu, Dr Raviprasad Aduri
Pathophysiological investigations of sickle cell disease focus on understanding its mechanisms, including hemoglobin polymerization, erythrocyte sickling, and vascular occlusion, leading to vaso-occlusive crises. Interventions aim to mitigate these abnormalities by promoting fetal hemoglobin production with therapies like hydroxyurea, enhancing oxygen delivery through transfusions, and exploring emerging gene therapies for a...
Pathophysiological investigations of sickle cell disease focus on understanding its mechanisms, including hemoglobin polymerization, erythrocyte sickling, and vascular occlusion, leading to vaso-occlusive crises. Interventions aim to mitigate these abnormalities by promoting fetal hemoglobin production with therapies like hydroxyurea, enhancing oxygen delivery through transfusions, and exploring emerging gene therapies for a potential cure. Additionally, targeted pharmacotherapies address inflammation, oxidative stress, and endothelial dysfunction. These efforts aim to alleviate symptoms, reduce complications, and improve the quality of life for individuals living with sickle cell disease, advancing treatment strategies in hemorheology and clinical management. (Biological Science)
Understanding the Role of Quantum Dotsas Tool for Tumour Imaging and as a Drug Carrier through in-vitro and in-silico Approach
12/01/2024
Inventors: Dr. Paramita Haldar, Dr Mrunalini Kawaduji
Gaydhane
Quantum dots (QDs) play a dual role in tumor imaging and drug delivery, explored through in vitro and in silico methodologies. In vitro, QDs labeled with targeting ligands allow precise tumor cell imaging via fluorescence or photoacoustic techniques, enhancing diagnostic accuracy. Additionally, QDs' tunable properties aid drug delivery; their size...
Quantum dots (QDs) play a dual role in tumor imaging and drug delivery, explored through in vitro and in silico methodologies. In vitro, QDs labeled with targeting ligands allow precise tumor cell imaging via fluorescence or photoacoustic techniques, enhancing diagnostic accuracy. Additionally, QDs' tunable properties aid drug delivery; their size and surface modifications optimize drug encapsulation and release. In silico simulations predict QDs' behavior in biological environments, guiding design for optimal tumor targeting and therapeutic efficacy. This interdisciplinary approach leverages QDs' unique characteristics for precise imaging and targeted drug delivery, advancing personalized medicine and cancer treatment strategies. (Chemical Engineering)
Development Of FPGA- Based Communication Transceiver For Aerial Vehicles
20/01/2024
Inventors: Dr. Vipin Kizheppatt
The development of an FPGA-based communication transceiver for aerial vehicles involves designing a compact, robust hardware platform capable of integrating diverse communication protocols like WiFi, LTE, or custom RF standards. FPGA technology enables efficient signal processing, modulation/demodulation, and adaptive filtering for reliable data transmission in dynamic airborne environments. Emphasizing low...
The development of an FPGA-based communication transceiver for aerial vehicles involves designing a compact, robust hardware platform capable of integrating diverse communication protocols like WiFi, LTE, or custom RF standards. FPGA technology enables efficient signal processing, modulation/demodulation, and adaptive filtering for reliable data transmission in dynamic airborne environments. Emphasizing low power consumption and high reliability, the transceiver facilitates real-time communication between UAVs and ground stations, supporting applications such as remote sensing, surveillance, and autonomous flight operations. Rigorous testing ensures performance under varying conditions, while compliance with aviation standards ensures safe and effective integration into UAV systems. (EEE)
Modeling and CFD Simulation of a Batch Reactor with Heating and Cooling Limpet Coils used for the Production of Resins
12/01/2024
Inventors: Dr. Amol Deshpande, Dr. S D Manjare
Modeling and CFD simulation of a batch reactor with heating and cooling limpet coils for resin production involves accurately modeling fluid dynamics, heat transfer, and chemical reactions. The reactor's geometry, including coils and baffles, is simulated to optimize temperature control and mixing efficiency. Navier-Stokes equations govern fluid flow, considering turbulent...
Modeling and CFD simulation of a batch reactor with heating and cooling limpet coils for resin production involves accurately modeling fluid dynamics, heat transfer, and chemical reactions. The reactor's geometry, including coils and baffles, is simulated to optimize temperature control and mixing efficiency. Navier-Stokes equations govern fluid flow, considering turbulent effects induced by coils. Conjugate heat transfer analysis accounts for interactions between reactor contents, coils, and ambient conditions, crucial for predicting temperature distributions. Simulation results guide reactor design adjustments for enhanced resin production efficiency, ensuring precise control of process variables and optimizing batch-to-batch consistency in industrial resin manufacturing. (Chemical Engineering)
Robust and Optimal Decentralized Control Algorithms for Complex Distillery Systems
29/11/2023
Inventors: Dr. Saroj Sundar Baral
Robust decentralized control algorithms for complex distillery systems optimize performance through hierarchical structures where subsystems manage local operations independently yet coordinate effectively. These algorithms integrate distributed optimization techniques like decentralized MPC, ensuring efficient regulation of processes such as fermentation and distillation. They also incorporate fault tolerance mechanisms and real-time data...
Robust decentralized control algorithms for complex distillery systems optimize performance through hierarchical structures where subsystems manage local operations independently yet coordinate effectively. These algorithms integrate distributed optimization techniques like decentralized MPC, ensuring efficient regulation of processes such as fermentation and distillation. They also incorporate fault tolerance mechanisms and real-time data integration to maintain stability and adapt to dynamic conditions. By enhancing resilience and operational efficiency, these algorithms streamline production processes, improve product quality, and mitigate risks, supporting reliable and sustainable operation of distillery facilities while meeting stringent regulatory requirements. (Chemical Engineering)
Development Of A Biomolecule Detection System With On-Chip Planar Hall Magnetometer For Diagnostic Uses
04/09/2023
Inventors: Dr. Arnab Roy
The development of a biomolecule detection system with an on-chip planar Hall magnetometer (PHM) offers a sensitive and miniaturized platform for diagnostic applications. PHMs, integrated on a microfluidic chip, detect biomolecules such as proteins, DNA, or viruses through their magnetic signatures. Functionalized magnetic nanoparticles or magnetic labels bind to target...
The development of a biomolecule detection system with an on-chip planar Hall magnetometer (PHM) offers a sensitive and miniaturized platform for diagnostic applications. PHMs, integrated on a microfluidic chip, detect biomolecules such as proteins, DNA, or viruses through their magnetic signatures. Functionalized magnetic nanoparticles or magnetic labels bind to target biomolecules, altering the magnetic field detected by the PHM. This change is quantified to determine biomolecule concentration or presence, enabling rapid and sensitive diagnostics. The system's small size, low power consumption, and compatibility with microfluidic devices make it suitable for point-of-care testing, environmental monitoring, and biomedical research, advancing healthcare accessibility and efficiency. (Physics)
Applications of Supervised Machine learning Algorithms to Analyze the Drivers of Early stage Entrepreneurial Activities in India: The Role of Socio- cognitive Traits and Institutional Environments
23/11/2023
Inventors: Dr. Aswini Kumar Mishra, Dr. Rajorshi Sen Gupta
Applying supervised machine learning algorithms to analyze the drivers of early-stage entrepreneurial activities in India provides valuable insights into socio-cognitive traits and institutional environments influencing entrepreneurship. Algorithms such as logistic regression, decision trees, and random forests can identify key predictors like education levels, risk perception, social networks, and regulatory frameworks...
Applying supervised machine learning algorithms to analyze the drivers of early-stage entrepreneurial activities in India provides valuable insights into socio-cognitive traits and institutional environments influencing entrepreneurship. Algorithms such as logistic regression, decision trees, and random forests can identify key predictors like education levels, risk perception, social networks, and regulatory frameworks affecting entrepreneurial decisions. By training on datasets encompassing socio-economic data and institutional indicators, these algorithms predict entrepreneurial success factors, informing policy interventions and educational strategies. This approach enhances understanding of India's entrepreneurial ecosystem, facilitating targeted support for aspiring entrepreneurs and fostering economic growth through informed policy and educational initiatives. (Economics and Finance)